Multiplex PCR for the concurrent detection and differentiation of Salmonella spp., Salmonella Typhi and Salmonella Typhimurium. by Chai, Fung Pui, Wong, Woan Chwen, Chai, Lay Ching, Lee, Hai Yen, Ahmad, Noorlis, Tuan Chilek, Tuan Zainazor, Tang, John Yew Huat, Mohd Ghazali, Farinazleen, Cheah, Yoke Kqueen, Nakaguchi, Yoshitsugu, Nishibuchi, Mitsuaki, Radu, Son

“…Salmonellosis outbreaks involving typhoid fever and human gastroenteritis are important diseases in tropical countries where hygienic conditions are often not maintained. …”
Get full text

Study on association factors of intestinal infectious diseases based-Bayesian spatio-temporal model by Yancen Zhan, Hua Gu, Xiuyang Li

“…High precipitation was associated with an increased risk of typhoid fever (RR: 1.52, 95%CI: 1.09-2.13), and high temperature was associated with an increased risk of typhoid fever (RR: 2.82, 95%CI: 2.06-3.89), paratyphoid fever (RR: 2.79, 95%CI: 2.02-3.90), and HMFD (RR: 1.34, 95%CI: 1.01-1.77). …”
Get full text

Dataset for the ACT-South ASIA protocol manuscript by Kestelyn, E

“…Additional data for the protocol manuscript: "Azithromycin and cefixime combination versus azithromycin alone for the out-patient treatment of clinically suspected or confirmed uncomplicated typhoid fever in South Asia; a randomised controlled trial". …”

Assessing the global risk of typhoid outbreaks caused by extensively drug resistant Salmonella Typhi by Joseph Walker, Chrispin Chaguza, Nathan D. Grubaugh, Megan Carey, Stephen Baker, Kamran Khan, Isaac I. Bogoch, Virginia E. Pitzer

“…Typhi) has become the dominant cause of typhoid fever in Pakistan. The establishment of sustained XDR S. …”
Get full text

Old tools, new applications: Use of environmental bacteriophages for typhoid surveillance and evaluating vaccine impact. by Yogesh Hooda, Shuborno Islam, Rathin Kabiraj, Hafizur Rahman, Himadree Sarkar, Kesia E da Silva, Rajan Saha Raju, Stephen P Luby, Jason R Andrews, Samir K Saha, Senjuti Saha

“…Typhoid-conjugate vaccines (TCVs) provide an opportunity to reduce the burden of typhoid fever, caused by Salmonella Typhi, in endemic areas. …”
Get full text

From intestine to beyond: Salmonella entry factors display distinct transcription pattern upon infection in murine models by Michaël Koczerka, Isabelle Lantier, Marie Morillon, Justine Deperne, Camille D. Clamagirand, Isabelle Virlogeux-Payant, Olivier Grépinet

“…An intense transcription of pagN was also observed in deep organs in the typhoid fever-like model, while that of T3SS-1 remained quite sporadic in these organs, and mainly focused on the intestine all along the infection. …”
Get full text

INFECTIONS TRANSFER FACTORS WITH THE SPREAD OF INTESTINAL DISEASES IN VARIOUS REGIONS OF THE REPUBLIC OF TAJIKISTAN by H.K. RAFIEV, S.T. IBODOV, M.S. TALABOV, G.M. USMANOVA, S.G. ALI-ZADE, N.B. LUKYANOV

“…Results: The dominance of the water factor under conditions of the specific weight of Flexner shigellosis during the period of under study ranged between 75-85%. Compared with typhoid fever and bacterial dysentery, the incidence of diarrhoea in the country during the analyzed period remains at a high enough level – from 629.0 to 1206.3, and in 2015, it rose sharply and reached 2150 per 100 thousand. …”
Get full text

Genetic dissection of the Ity3 locus identifies a role for Ncf2 co-expression modules and suggests Selp as a candidate gene underlying the Ity3.2 locus. by Rabia Tahir Khan, Rabia Tahir Khan, Marie eChevenon, Marie eChevenon, Kyoko E Yuki, Kyoko E Yuki, Danielle eMalo, Danielle eMalo, Danielle eMalo

“…Typhoid fever and salmonellosis, which are caused by Salmonella Typhi and Typhimurium respectively, are responsible for significant morbidity and mortality in both developed and developing countries. …”
Get full text

ANTIBACTERIAL ACTIVITY OF MANGOSTEEN BARK FRACTION (GARCINIA MANGOSTANA L.) SALMONELLA TYPHI ATCC 13311 by Salmah Wilujeng Anggraini, Vevi Maritha, Susanti Erikania

“…Background: Typhoid fever is caused by Salmonella typhi bacterial infection which spreads via the faecal-oral route and has epidemic potential. …”
Get full text

A Ten-Year Retrospective Survey of Antimicrobial Susceptibility Patterns among Salmonella enterica subsp. enterica Serovar Typhi Isolates in Ontario, Canada by Shawn T. Clark, Kirby Cronin, Antoine J. Corbeil, Samir N. Patel

“…ABSTRACT The epidemiology and treatment of typhoid fever are complicated by the emergence and spread of Salmonella enterica subsp. enterica serovar Typhi lineages with resistance to many antimicrobial agents critical for therapy. …”
Get full text

Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi by Thanh Duy, P, Thieu, NTV, Nguyen Thi Nguyen, T, Ngoc Dan Thanh, H, Dongol, S, Karkey, A, Carey, M, Basnyat, B, Dougan, G, Rabaa, MA, Baker, S

“…Despite recent advances in typhoid fever control, asymptomatic carriage of Salmonella Typhi in the gallbladder remains poorly understood. …”

Rapidly escalating hepcidin and associated serum iron starvation are features of the acute response to typhoid infection in humans by Darton, T, Blohmke, C, Giannoulatou, E, Waddington, C, Jones, C, Sturges, P, Webster, C, Drakesmith, H, Pollard, A, Armitage, A

“…However, the deployment of hepcidin in human bacterial infections remains poorly characterized. Typhoid fever is a globally significant, human-restricted bacterial infection, but understanding of its pathogenesis, especially during the critical early phases, likewise is poorly understood. …”

Challenge of humans with wild-type Salmonella enterica serovar Typhi elicits changes in the activation and homing characteristics of mucosal-associated invariant T cells. by Salerno-Goncalves, R, Luo, D, Fresnay, S, Magder, L, Darton, T, Jones, C, Waddington, C, Blohmke, C, Angus, B, Levine, M, Pollard, A, Sztein, M

“…In contrast, volunteers susceptible to the development of typhoid disease (TD) exhibited a sharp decline in circulating MAIT cells during the development of typhoid fever. Interestingly, MAIT cells from low-dose TD volunteers had higher levels of CD38 coexpressing CCR9, CCR6, and Ki67 during the development of typhoid fever than high-dose TD volunteers. …”

Salmonella Typhi Vi capsule prime-boost vaccination induces convergent and functional antibody responses by Dahora, LC, Verheul, MK, Williams, KL, Jin, C, Stockdale, L, Pollard, AJ, Cavet, G, Giladi, E, Hill, J, Kim, D, Leung, Y, Bobay, BG, Spicer, LD, Sawant, S, Rijpkema, S, Dennison, SM, Alam, SM, Tomaras, GD

“…Antibodies elicited by these vaccines are important for mediating protection against typhoid fever. However, the characteristics of protective and functional Vi antibodies are unknown. …”

Innovative Approaches Towards Development And Utilization Of Dna Diagnostics For Salmonella Typhi. by Ismail, Aziah

“…Demam kepialu berpunca daripada Salmonella Typhi kekal sebagai masalah kesihatan di negara-negara kurang membangun dan sedang membangun. Typhoid fever caused by Salmonella Typhi remains a public health problem in underdeveloped and developing countries. …”
Get full text

Spatial heterogeneity of socio-economic determinants of typhoid/paratyphoid fever in one province in central China from 2015 to 2019 by Xiang Ren, Siyu Zhang, Piaoyi Luo, Jin Zhao, Wentao Kuang, Han Ni, Nan Zhou, Haoyun Dai, Xiuqin Hong, Xuewen Yang, Wenting Zha, Yuan Lv

“…Abstract Background Typhoid fever and paratyphoid fever are one of the most criticial public health issues worldwide, especially in developing countries. …”
Get full text

Early host immune responses in a human organoid-derived gallbladder monolayer to Salmonella Typhi strains from patients with acute and chronic infections: a comparative analysis by Rosângela Salerno-Goncalves, Haiyan Chen, Andrea C. Bafford, Mariana Izquierdo, Juan Carlos Hormazábal, Rosanna Lagos, Hervé Tettelin, Adonis D’Mello, Jayaum S. Booth, Alessio Fasano, Myron M. Levine, Marcelo B. Sztein, Marcelo B. Sztein

“…Typhi), a human-restricted pathogen, invades the host through the gut to cause typhoid fever. Recent calculations of the typhoid fever burden estimated that more than 10 million new typhoid fever cases occur in low and middle-income countries, resulting in 65,400-187,700 deaths yearly. …”
Get full text

Typhoidal salmonella disease in Mukuru informal settlement, Nairobi Kenya; carriage, diversity, and antimicrobial resistant genes. by Purity Kasiano, Susan Kavai, Susan Kiiru, Andrew Nyerere, Samuel Kariuki

“…<h4>Introduction</h4>Multiple studies have shown that typhoid fever is endemic in developing countries characterized by poor hygiene. …”
Get full text

Organic acids and 2,4-Di-tert-butylphenol: major compounds of Weissella confusa WM36 cell-free supernatant against growth, survival and virulence of Salmonella Typhi by Wattana Pelyuntha, Chaiyavat Chaiyasut, Duangporn Kantachote, Sasithorn Sirilun

“…Typhi), the causative agent of typhoid fever, causes serious systemic disease in humans. …”
Get full text

Widal test interpretation in COVID-19 patients: a study from a dedicated COVID center by Bineeta Kashyap, Nadeem Ahmad, Rajat Jhamb, Kapil Chaudhary

“…Conclusion: Documenting the prevalence of typhoid fever, especially during the COVID-19 pandemic, is very difficult. …”
Get full text