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The Unfolded Protein Response: An Overview
Published 2021-04-01“…The unfolded protein response is the mechanism by which cells control endoplasmic reticulum (ER) protein homeostasis. …”
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New twists in the unfolded protein response
Published 2012-10-01Subjects: “…Unfolded Protein Response…”
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The unfolded protein response in virus infections.
Published 2014-09-01Subjects: Get full text
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Tidy up - The unfolded protein response in sepsis
Published 2022-10-01Subjects: Get full text
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The unfolded protein response is required for dendrite morphogenesis
Published 2015-06-01Subjects: Get full text
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Progression of unfolded protein response and ferroptosis in angiogenesis
Published 2024-04-01Subjects: Get full text
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Unfolded Protein Responses With or Without Unfolded Proteins?
Published 2012-11-01Subjects: “…unfolded protein response…”
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The physiological role of the unfolded protein response in the nervous system
Published 2024-01-01Subjects: “…myelin; neuron; oligodendrocyte; schwann cell; unfolded protein response…”
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An Emerging Role for the Unfolded Protein Response in Pancreatic Cancer
Published 2021-01-01Subjects: Get full text
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The Unfolded Protein Response as a Guardian of the Secretory Pathway
Published 2021-10-01“…The ER is also a hotspot of lipid biosynthesis including sterols, glycerophospholipids, ceramides and neural storage lipids. The unfolded protein response (UPR) bears an evolutionary conserved, dual sensitivity to both protein-folding imbalances in the ER lumen and aberrant compositions of the ER membrane, referred to as lipid bilayer stress (LBS). …”
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Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy
Published 2022-03-01Subjects: “…unfolded protein response…”
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Fundamental and Applicative Aspects of the Unfolded Protein Response in Yeasts
Published 2023-10-01Subjects: Get full text
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The role of the unfolded protein response in dengue virus pathogenesis
Published 2017“…Host-viral interactions play a significant role in deciding the fate of the infection. The unfolded protein response (UPR) is a pro-survival cellular reaction induced in response to DENV mediated ER stress. …”
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Unfolded protein responses in models of Motor Neuron Disease
Published 2010“…Misfolded mutant SOD1 accumulates in the cytosol and mitochondrial intermembrane space (IMS) indicating the involvement of unfolded protein responses in ALS pathogenesis.</p><p>Unfolded protein responses (UPRs) are complex signal transduction cascades which detect perturbations in protein folding and couple them to the expression of protein quality control machinery thereby allowing individual compartments to adapt to stress. …”
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The unfolded protein response protects from tau neurotoxicity in vivo.
Published 2010-09-01“…The unfolded protein response is a critical system by which the cell handles excess misfolded protein in the secretory pathway. …”
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Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases
Published 2020-08-01Subjects: Get full text
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Unfolded protein response in balancing plant growth and stress tolerance
Published 2022-10-01Subjects: “…UPR – unfolded protein response…”
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Transcriptional regulation of VEGF-A by the unfolded protein response pathway.
Published 2010-03-01“…IRE1alpha, PERK, and ATF6alpha, master regulators of the unfolded protein response (UPR), are activated under these conditions and are proposed to have a role in mediating angiogenesis.Here we show that IRE1alpha, PERK, and ATF6alpha powerfully regulate VEGFA mRNA expression under various stress conditions. …”
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