Showing 1 - 20 results of 1,403 for search '"unfolded protein response"', query time: 0.25s Refine Results
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    The Unfolded Protein Response: An Overview by Adam Read, Martin Schröder

    Published 2021-04-01
    “…The unfolded protein response is the mechanism by which cells control endoplasmic reticulum (ER) protein homeostasis. …”
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    Article
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    New twists in the unfolded protein response by Benedict C S Cross, David Ron

    Published 2012-10-01
    Subjects: “…Unfolded Protein Response…”
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    Article
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    Unfolded Protein Responses With or Without Unfolded Proteins? by Erik L. Snapp

    Published 2012-11-01
    Subjects: “…unfolded protein response…”
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    Article
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    The physiological role of the unfolded protein response in the nervous system by Shuangchan Wu, Wensheng Lin

    Published 2024-01-01
    Subjects: “…myelin; neuron; oligodendrocyte; schwann cell; unfolded protein response…”
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    Article
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    The Unfolded Protein Response as a Guardian of the Secretory Pathway by Toni Radanović, Robert Ernst

    Published 2021-10-01
    “…The ER is also a hotspot of lipid biosynthesis including sterols, glycerophospholipids, ceramides and neural storage lipids. The unfolded protein response (UPR) bears an evolutionary conserved, dual sensitivity to both protein-folding imbalances in the ER lumen and aberrant compositions of the ER membrane, referred to as lipid bilayer stress (LBS). …”
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    Article
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    The role of the unfolded protein response in dengue virus pathogenesis by Perera, G, Miller, J, Zitzmann, N

    Published 2017
    “…Host-viral interactions play a significant role in deciding the fate of the infection. The unfolded protein response (UPR) is a pro-survival cellular reaction induced in response to DENV mediated ER stress. …”
    Journal article
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    Unfolded protein responses in models of Motor Neuron Disease by Kwok, A

    Published 2010
    “…Misfolded mutant SOD1 accumulates in the cytosol and mitochondrial intermembrane space (IMS) indicating the involvement of unfolded protein responses in ALS pathogenesis.</p><p>Unfolded protein responses (UPRs) are complex signal transduction cascades which detect perturbations in protein folding and couple them to the expression of protein quality control machinery thereby allowing individual compartments to adapt to stress. …”
    Thesis
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    The unfolded protein response protects from tau neurotoxicity in vivo. by Carin A Loewen, Mel B Feany

    Published 2010-09-01
    “…The unfolded protein response is a critical system by which the cell handles excess misfolded protein in the secretory pathway. …”
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    Article
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    Transcriptional regulation of VEGF-A by the unfolded protein response pathway. by Rajarshi Ghosh, Kathryn L Lipson, Karen E Sargent, Arthur M Mercurio, Joan S Hunt, David Ron, Fumihiko Urano

    Published 2010-03-01
    “…IRE1alpha, PERK, and ATF6alpha, master regulators of the unfolded protein response (UPR), are activated under these conditions and are proposed to have a role in mediating angiogenesis.Here we show that IRE1alpha, PERK, and ATF6alpha powerfully regulate VEGFA mRNA expression under various stress conditions. …”
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    Article