Delayed appearance of hepatic artery pseudoaneurysm and an arterio-biliary fistula secondary to biliary leakage and bilioma formation in a liver trauma patient and its management t... by Biswajit Sahoo, Pankaj Kumar, Pradeep Kumar Singh, Prakash Kumar Sasmal, Manoj Kumar Nayak, Krantisurya Mane

“…In the present case, there were no clinical features of hemobilia or upper gastrointestinal bleeding. Moreover, the hepatic artery pseudoaneurysm and arterio-biliary fistula evolved after a latent period of a few weeks, secondary to the toxic effects of the bile on the vessel walls due to biloma formation or biliary leakage, which is exceptionally uncommon. …”
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Case Report: PROS1 (p.Leu584Arg) pathogenic mutation causes portal and superior mesenteric venous thromboembolism by Peng Ding, Yuan Zhou, Kai-Chen Zhang, Sheng Li, Kun-lan Long, Jun Chen, Ying-jie Chen, Pei-yang Gao

“…He was diagnosed with “portal and superior mesenteric vein thrombosis, small bowel obstruction and necrosis, acute upper gastrointestinal bleeding (UGIB), hemorrhagic shock.” Serum protein S levels were decreased, and gene sequencing revealed a heterozygous missense mutation in PROS1, c.1571T > G (p.Leu584Arg). …”
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Plasma urea:creatinine ratio as a biomarker of gastrointestinal bleeding in dogs with anaemia by Ben Safrany, Andrea C. Holmes, Sophie Adamantos, Caroline Kisielewicz, Florence Juvet, Laura Macfarlane, Theresa McCann, Paula Valiente Diana, Fergus Allerton

“…Plasma urea:creatinine ratio is an accepted biomarker of upper gastrointestinal bleeding in human medicine. Objectives The objective of this study was to evaluate plasma urea:creatinine ratio as a biomarker of gastrointestinal bleeding in a population of dogs with anaemia. …”
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“…BackgroundTibet is located on the plateau with a high incidence of peptic ulcer bleeding, but there are few reports about the clinical characteristics of peptic ulcer bleeding, as well as the risk factors of bleeding and rebleeding associated with peptic ulcer in Tibet.ObjectiveTo explore the clinical characteristics of peptic ulcer bleeding, and the potential risk factors of bleeding and rebleeding associated with high-risk peptic ulcer in Tibet.MethodsA total of 212 hospitalized patients who visited the Tibet Autonomous Region People's Hospital for upper gastrointestinal bleeding and were clearly diagnosed as peptic ulcer bleeding by gastroscopy from 2017 to 2020 were selected. …”
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Surgical Treatment of Persistent Pseudomonas aeruginosa Bacteraemia After n-Butyl-2-cyanoacrylate for Gastric Bleeding Varices by Abiu Sempere, Gabriela Chullo, Sabina Herrera, Jorge Boán, Elisa Pose, María Londoño, Virginia Hernandez-Gea, Miguel Ángel Verdejo, Juan Carlos García-Valdecasas, Cristina Pitart, Yiliam Fundora, Alex Soriano, Marta Bodro

“…We report the case of a 34-year-old man with history of cirrhosis due to Wilson’s disease and severe portal hypertension who was hospitalized as a result of upper gastrointestinal bleeding secondary to fundic varices that were treated with NCBA. …”
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A novel scoring system for prediction of esophageal varices in critically ill patients by Hanafy AS, Badawi R, Basha MAA, Selim A, Yousef M, Elnawasany S, Mansour L, Elkhouly RA, Hawash N, Abd-Elsalam S

“…The aim was to validate a novel scoring system for risk stratification for urgency of GIT endoscopy in critically ill patients.Methods: This is an observational study conducted from January 2013 to January 2016 to analyze 300 patients with critical medical conditions and presenting with upper gastrointestinal bleeding. Meticulous clinical, laboratory, and sonographic evaluations were performed to calculate Glasgow Blatchford score (GBS) and variceal metric score for risk stratification and prediction of the presence of esophageal varices (OV). …”
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Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice by Moore, R, Derry, S, Phillips, C, McQuay, H

“…Results: Evidence of efficacy of coxibs compared to NSAIDs for upper gastrointestinal bleeding was strong, with consistent reductions in events of about 50% in large randomised trials (34,460 patients), meta-analyses of randomised trials (52,474 patients), and large observational studies in clinical practice (3,093 bleeding events). …”

Indications and Findings of Upper Gastrointestinal Endoscopy at a Tertiary Hospital in Ethiopia: A Cross-Sectional Study by Argaw AM, Ethiopia SS, Lelisa G, Fisseha H, Mulugeta B

“…Dyspepsia (27.8%) was the most common indication for upper gastrointestinal endoscopic evaluation, followed by upper gastrointestinal bleeding (17.1%), and screening for varices (16.8%). …”
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Duodenal Ulcer with Massive Gastrointestinal Hemorrhage as an Initial Manifestation in Multiple Myeloma with Extramedullary Disease: A Case Report by Hao-Tse Chiu, Po-Huang Chen, Hao Yen, Chao-Yang Chen, Chih-Wei Yang, Yu-Hong Liu, Wu-Feng Hsieh, Shih-Hao Chou, Ta-Wei Pu

“…The patient’s condition was initially diagnosed as small bowel obstruction, upper gastrointestinal bleeding, severe anemia, acute renal failure, and hypercalcemia. …”
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Panax notoginseng preparation plus aspirin versus aspirin alone on platelet aggregation and coagulation in patients with coronary heart disease or ischemic stroke: A meta-analysis... by Lulu Dai, Ying Zhang, Yuerong Jiang, Keji Chen

“…Compared with ASA alone, PNP plus ASA had a stronger inhibitory effect on in PAgR [PNS, WMD = −6.10 (−7.25, −4.95), p < 0.00001; PTS, WMD = −3.53 (−4.68, −2.38), p < 0.00001]; PNS plus ASA better reduced FIB [WMD = −0.43 (−0.49, −0.36)] and DD [WMD = −0.59 (−0.67, −0.51), p < 0.00001], while PLT (p = 0.07) and PT (p = 0.34) were not significantly different; PTS plus ASA better prolonged PT [WMD = 1.90 (1.47, 2.32), p < 0.00001] and PT-INR [WMD = 0.22 (0.11, 0.32), p < 0.0001], whereas no significant difference in DD (p = 0.1) and bleeding-related events (positive fecal occult blood, p = 0.96; upper gastrointestinal bleeding, p = 0.67; subcutaneous hemorrhage, p = 0.51; bulbar conjunctival hemorrhage, p = 0.51; hematuria, p = 0.58). …”
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P- 57 SURVIVAL AND LIVER TRANSPLANTATION FOR PATIENTS WITH ACUTE ON CHRONIC LIVER FAILURE IN URUGUAY by Martín Elizondo, Romina Rey, Victoria Mainardi, María Clara Gouarnalusse, Marcelo Valverde, Solange Gerona

“…In 64% of patients, a precipitating cause was identified: intercurrent infection in 13, upper gastrointestinal bleeding in 5, and acute alcoholic hepatitis in 2. …”
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Transarterial Embolization for Active Gastrointestinal Bleeding: Predictors of Early Mortality and Early Rebleeding by Chloé Extrat, Sylvain Grange, Alexandre Mayaud, Loïc Villeneuve, Clément Chevalier, Nicolas Williet, Bertrand Le Roy, Claire Boutet, Rémi Grange

“…Results: Sixty-eight patients were included: 55 (80.9%) experienced upper gastrointestinal bleeding and 13 (19.1%) lower gastrointestinal bleeding. …”
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Influence of COVID-19 on Patients with Esophageal Varices under Prophylactic Endoscopic Band Ligation Therapy by Ana Craciun, Inês Botto, Joao Lopes, Miguel Moura, Sofia Carvalhana, Helena Cortez-Pinto, Rui Tato Marinho

“…Background and Objectives: Endoscopic band ligation (EBL) plays a critical role in patients with clinically significant portal hypertension, as variceal eradication (VE) is essential to prevent further variceal upper gastrointestinal bleeding (GI). The emergence of COVID-19 has led to a dramatic reduction in endoscopic activity. …”
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Segmental portal hypertension secondary to chronic pancreatitis by Karla Correa-Cedeño, Carlos M. Martinez-Escanamé, Carlos A. de-la-Torre-Cabral, Viviana Herrera-Muñoz, Graciela Rodriguez-Gonzalez, Diego Alejandro-Martinez

“…He was admitted to the emergency department with clinical symptoms compatible with upper gastrointestinal bleeding due to the presence of melaenic bowel movements on multiple occasions, associated with anemic syndrome, biochemically highlighting a Hb of 2.4 mg/dl, with normal liver function tests and other laboratories, with no changes of chronic hepatopathy by ultrasound. …”
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Transcatheter Arterial Embolization in Acute Non-Variceal Gastrointestinal Bleedings: A Ten-Year Single-Center Experience in 91 Patients and Review of the Literature by Federico Fontana, Filippo Piacentino, Christian Ossola, Andrea Coppola, Marco Curti, Edoardo Macchi, Giuseppe De Marchi, Chiara Floridi, Anna Maria Ierardi, Gianpaolo Carrafiello, Sergio Segato, Giulio Carcano, Massimo Venturini

“…Objective: To report the safety and efficacy of trans-arterial embolization (TAE) for upper gastrointestinal bleeding (UGIB) and lower gastrointestinal bleeding (LGIB) due to different etiologies in 91 patients for ten years. …”
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Endovascular brachytherapy with iodine-125 seed strand for extensive portal vein tumor thrombus in patients with hepatocellular carcinoma by Zhongbao Tan, Daguang Wu, Daguang Wu, Jinhe Guo, Huanjing Wang, Jian Zhang

“…Six patients died of upper gastrointestinal bleeding: four patients in the I-125 seed strand alone group and two patients in the combination of I-125 seed strand with systematic treatment group.ConclusionsThe study shows that endovascular brachytherapy with I-125 seed strand implantation is a safe and effective treatment method for extensive PVTT in HCC patients. …”
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Diagnosis and treatment modalities of hilar biliary duct stricture in hepatic cystic echinococcosis after endocystectomy by Shalayiadang Paizula, Abulizi Abduaini, Ahan Ayifuhan, Jiang Tiemin, Ran Bo, Zhang Ruiqing, Guo Qiang, Wen Hao, Shao Yingmei, Aji Tuerganaili

“…Among type A patients, one patient died of organ failure, and upper gastrointestinal bleeding and liver abscess occurred in one patient. …”
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Optimal Operational Definition of Patient with Peptic Ulcer Bleeding for Big Data Analysis Using Combination of Clinical Characteristics in a Secondary General Hospital by Jae Won Lee, Hyun Ki Kim, Yong Sik Woo, Jaehoon Jahng, Young Ran Jin, Jong Heon Park, Yong Sung Kim, Hwoon-Yong Jung

“…Background : /Aims: Peptic ulcer bleeding (PUB) is the most common cause of upper gastrointestinal bleeding in Korea but there has been no research done using big data. …”
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Investigation of the efficacy and safety of cryoablation and intra-arterial PD-1 inhibitor in patients with advanced disease not responding to checkpoint inhibitors: An exploratory... by Fuqun Wei, Rui Guo, Yuan Yan, Ruixiang Lin, Jin Chen, Zhengyu Lin, Zhengyu Lin

“…Treatment-related severe adverse events included one case of abdominal infection and one case of upper gastrointestinal bleeding, which were cured after the intervention. …”
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Use of Non-steroidal Anti-inflammatory Drugs (NSAIDs) and their Increased Risk on Gastrointestinal (GI) Bleeding by Abdullah Sohail

“…There is also a higher risk associated with the concurrent use of SSRIs and NSAIDs.4 Gastrointestinal bleeding is a serious complication of NSAID use, as it can lead to hospitalization and even death due to the high mortality rate associated with its use.5 A retrospective study conducted in Pakistan found that the most common cause of upper gastrointestinal bleeding in our population other than infections and ulcers, was a 35% history of unmonitored NSAID use.6 These studies highlight the importance of understanding the risks associated with NSAID use, particularly in populations where these drugs are frequently used. …”
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