Predictive value of cystatin C-based estimated glomerular filtration rate combined with thromboelastogram for clinical prognosis of acute-on-chronic liver failure by Ba Zhiwei, Zhao Wen, Liu Chuanmiao

“…ACLF intra-group analysis showed that MA and eGFR-CysC were significantly different between patients with or without acute renal injury （both P < 0.05）， R and MA were significantly different between patients with or without upper gastrointestinal bleeding （both P < 0.05）， MA and eGFR-CysC significantly differed between the death and survival groups （both P < 0.05）. …”
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Relationship between the D-dimer and von Willebrand factor levels and the development of gastrointestinal bleeding in patients with stable coronary artery disease: data from the re... by O. O. Shakhmatova, A. L. Komarov, V. V. Korobkova, E. V. Titaeva, A. B. Dobrovolskiy, E. B. Yarovaya, A. G. Shuleshova, E. P. Panchenko

“…To study the role of von Willebrand factor (VWF) and D-dimer (DD) as predictors of upper gastrointestinal bleeding (GIB) in patients with stable coronary artery disease (CAD).Material and methods. …”
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Recurrent gastric antral vascular ectasia: a single center experience by Andrea Cavallaro, Antonio Zanghì, Maria Di Vita, Vito Emanuele Catania, Giovanni Longo, Emanuele Lo Menzo, Roberta Granata, Maria Rosaria Valenti, Alessandro Cappellani, Simone Di Majo

“…This condition accounts for ∼4% of upper gastrointestinal bleeding cases. This disease is often associated with systemic diseases, such as liver cirrhosis, chronic kidney failure, autoimmune conditions, diabetes mellitus, hypothyroidism, and cardiovascular diseases. …”
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Gastrointestinal bleeding in children: diagnosis, analysis, and structure by V.A. Dihtiar, M.V. Savenko, O.M. Barsuk, S.O. Shchudro, M.O. Kaminska

“…Purpose - to investigate the prevalence and analyze changes in the structure of GIT diseases in children complicated by upper gastrointestinal bleeding (GIB), based on esophagogastroduodenoscopy (EGD) data. …”
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The clinical applicability of percutaneous splenic vein stent implantation for pancreatic portal hypertension by Jingjing Liu, Qingbing Wang, Xiaoyi Ding, Qin Liu, Wei Huang, Junwei Gu, Zhongmin Wang, Wei Wu, Zhiyuan Wu

“…However, in the conservative group, the incidence of portal hypertensive gastropathy and upper gastrointestinal bleeding were 50% and 25%. In the stent group, all the varicose veins at the base of the stomach had shrunk by varying degrees, and the red color signs regressed. …”
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Bleeding Peptic Ulcer – Tertiary Center Experience: Epidemiology, Treatment and Prognosis by Ivan Budimir, Sanja Stojsavljević, Davor Hrabar, Dominik Kralj, Alen Bišćanin, Lora Stanka Kirigin, Mario Zovak, Žarko Babić, Sven Bohnec, Ivan Budimir Jr

“…The aim of this study was to demonstrate epidemiological, clinical and endoscopic characteristics of acute upper gastrointestinal bleeding (UGIB) with special reference to peptic ulcer bleeding (PUB). …”
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Delirium and Its Association with Short- and Long-Term Health Outcomes in Medically Admitted Patients: A Prospective Study by Aisha Ramadhan Al Huraizi, Juhaina Salim Al-Maqbali, Rajaa Saleh Al Farsi, Khalfan Al Zeedy, Taif Al-Saadi, Noof Al-Hamadani, Abdullah M. Al Alawi

“…Delirium caused a higher frequency of high-dependency unit (HDU) or intensive care unit (ICU) admission (<i>p</i> < 0.01) and an increased incidence of hospital-acquired complications, including infections (<i>p</i> = 0.03), pressure injuries (<i>p</i> = 0.01), and upper gastrointestinal bleeding (<i>p</i> < 0.01). Inpatient all-cause mortality was higher in patients with delirium than those without delirium (16.3% vs. 1.5%; <i>p</i> < 0.01). …”
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Risk factors and outcomes of gastrointestinal bleeding in patients with stable coronary artery disease: data from the observational registry of long-term antithrombotic therapy REG... by A. L. Komarov, O. O. Shakhmatova, V. V. Korobkova, E. S. Novikova, E. V. Guskova, E. B. Yarovaya, T. V. Balachonova, A. G. Shuleshova, E. P. Panchenko

“…To optimize the upper gastrointestinal bleeding (UGIB) risk scale in patients Material and methods. …”
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Comparison of the clinical and prognosis risk factors between endoscopic resection and radical gastrectomy for early-stage gastric cancer by Qianze Dao, Ke Chen, Liang Zhu, Xiaoshan Wang, Mengding Chen, Jian Wang, Zhengguang Wang

“…No significant differences were observed in the postoperative complications such as upper gastrointestinal bleeding, perforation, incision hernia, reoperation and recurrence (P > 0.05). …”
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The Reduction of After-Hours and Weekend Effects in Upper Gastro-intestinal Bleeding Mortality During the COVID-19 Pandemic Compared to the Pre-Pandemic Period by Cazacu SM, Turcu-Stiolica A, Florescu DN, Ungureanu BS, Iovanescu VF, Neagoe CD, Burtea DE, Genunche-Dumitrescu AV, Avramescu TE, Iordache S

“…Sergiu Marian Cazacu,1,&ast; Adina Turcu-Stiolica,2,&ast; Dan Nicolae Florescu,1,&ast; Bogdan Silviu Ungureanu,1,&ast; Vlad Florin Iovanescu,1,&ast; Carmen Daniela Neagoe,3,&ast; Daniela Elena Burtea,1,&ast; Amelia Valentina Genunche-Dumitrescu,3,&ast; Taina Elena Avramescu,4,&ast; Sevastita Iordache1,&ast; 1Gastroenterology Department, University of Medicine and Pharmacy Craiova, Clinical Emergency Hospital Craiova, Dolj County, Romania; 2Biostatistics Department, University of Medicine and Pharmacy Craiova, Dolj County, Romania; 3Internal Medicine Department, University of Medicine and Pharmacy Craiova, Clinical Emergency Hospital Craiova, Dolj County, Romania; 4Individual Sports, and Medical Disciplines Departments, University of Craiova, Dolj County, Romania&ast;These authors contributed equally to this workCorrespondence: Carmen Daniela Neagoe, Tel +40723767106, Email dananeagoe2014@gmail.com; daniela.neagoe@umfcv.roBackground: In upper gastrointestinal bleeding (UGIB), admissions after normal working hours and during weekends may be associated with increased mortality.Aim: To assess the evolution of the after-hours and weekend effects during the COVID-19 pandemic as a result of progressive improved management despite management challenges during the pandemic.Methods: We performed an observational study of patients admitted for UGIB at a tertiary academic center between March 2020 and December 2021, compared to the corresponding timeframe before the pandemic. …”
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Efficacy, Safety, and Clinical Outcomes of Splenorenal Shunt Surgery as a Therapeutic Intervention for Portal Hypertension Patients by Yan Efrata Sembiring, Heroe Soebroto, Ito Puruhito, Dhihintia Jiwangga Suta Winarno, I Gusti Agung Made Adnyanya Putra2, Sri Pramesthi Wisnu Bowo Negoro, Ketut Putu Yasa, Jeffrey Jeswant Dillon

“…The splenorenal shunt surgery is a potential intervention that may be considered for portal hypertension patients with clinical symptoms such as upper gastrointestinal bleeding caused by the rupture of gastro-esophageal varices. …”
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Evaluating physicians’ awareness and prescribing trends regarding proton pump inhibitors: a cross-sectional study by Sarya Swed, Hidar Alibrahim, Haidara Bohsas, Ahmed R. N. Ibrahim, Abdelmonem Siddiq, Nagham Jawish, Mark Hasib Makhoul, Maram Abdulmajid Mahmoud Alrezej, Fouad Hasib Makhoul, Bisher Sawaf, Wael Hafez, Wael Hafez, Sarah Makram Elsayed, Rami Soliman, Engy A. Wahsh

“…Therefore, assessing physicians’ knowledge and practice regarding PPI usage is critical for paving the way toward targeted recommendations and efforts.Objective: This study aimed to assess Syrian physicians’ perceptions of proton pump inhibitors adverse effects, their benefit in upper gastrointestinal bleeding (UGIB) prophylaxis, and how these perceptions are related to PPI prescription practice.Methods: A cross-sectional study was performed using a web-based questionnaire distributed among Syrian physicians in internal medicine between 28 November and 23 December 2022. …”
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Comparison of the Degree of Gastric Mucosal Injury between Patients Who Are Receiving Dual Antiplatelet Therapy or Single Antiplatelet Therapy by Yuji Shimada, Mariko Hojo, Yuji Kita, Yuji Ikeda, Sho Sato, Ayato Murata, Shunsuke Sato, Kohei Matsumoto, Yoichi Akazawa, Tsutomu Takeda, Kumiko Ueda, Hiroya Ueyama, Tomoyoshi Shibuya, Takuya Genda, Akihito Nagahara

“…Background: Patients taking low-dose aspirin have a higher incidence of gastroduodenal ulcers and higher risk of upper gastrointestinal bleeding than patients who do not. Thienopyridine antiplatelet agents may similarly cause bleeding gastroduodenal erosions and ulcers. …”
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Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy by Tzung-Jiun Tsai, Kwok-Hung Lai, Ping-I. Hsu, Chiun-Ku Lin, Hoi-Hung Chan, Hsien-Chung Yu, Huay-Min Wang, Kung-Hung Lin, Kai-Ming Wang, Shiuh-Nan Chang, Chun-Peng Liu, Shin-Hung Hsiao, Hung-Ru Huang, Ching-Huang Lin, Feng-Woei Tsay

“…Clopidogrel is associated with a high incidence of upper gastrointestinal bleeding in high-risk patients. However, the characteristic upper gastrointestinal lesions in symptomatic clopidogrel users remain unclear. …”
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Experiencia del manejo de la obstrucción al tracto de salida gástrico de origen neoplásico en pacientes del Hospital Universitario San Ignacio (HUSI) en Bogotá, Colombia by A.F. Ovalle-Hernández, R.D. Vargas-Rubio

“…Results: Patients sought medical consultations for the symptoms of vomiting, abdominal pain, weight loss, and upper gastrointestinal bleeding. Ninety-five percent of the patients in the SEMS group and 64.3% in the SGJ group presented with metastasis. …”
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Evaluación del uso de los inhibidores de la bomba de protones en un servicio de medicina interna Assessing the use of proton pump inhibitors in an internal medicine department by E. Martín-Echevarría, A. Pereira Juliá, M. Torralba, G. Arriola Pereda, P. Martín Dávila, J. Mateos, M. Rodríguez Zapata

“…Appropriate indications include: Gastroesophageal reflux, acute upper gastrointestinal bleeding, erosive gastritis or esophagitis, dyspepsia, NSAID-related gastropathy, and stress ulcer prophylaxis in high risk patients. …”
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The effect of anti-PD-1/PD-L1 antibodies combined with VEGF receptor tyrosine kinase inhibitors versus bevacizumab in unresectable hepatocellular carcinoma by Hui Zeng, Qi Xu, Jinyu Wang, Xiaoqing Xu, Jun Luo, Lei Zhang, Cong Luo, Jieer Ying, Jingjing Li

“…Patients who received ICI+BEV were more prone to upper gastrointestinal bleeding (2 [7%]), with one patient with grade 4 requiring emergency DSA treatment.ConclusionThis study found that ICI+TKI and ICI+BEV as first-line treatments were similar in OS, PFS, and tumor response in uHCC. …”
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Profilaxis de las úlceras de estrés en niños críticos: necesidad de replantear su uso rutinario by Sohair Sayed Abu El-Ella, Muhammad Said El-Mekkawy, Ali Mohamed Selim

“…The primary outcome was development of upper gastrointestinal bleeding or nosocomial infection. Results: The incidence of gastrointestinal bleeding was 27.1%, but clinically significant bleeding developed in only 5.6% of patients. …”
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Stress ulcer prophylaxis for critically ill children: routine use needs to be re-examined by Sohair Sayed Abu El-Ella, Muhammad Said El-Mekkawy, Ali Mohamed Selim

“…The primary outcome was development of upper gastrointestinal bleeding or nosocomial infection. Results: The incidence of gastrointestinal bleeding was 27.1%, but clinically significant bleeding developed in only 5.6% of patients. …”
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TC-325 hemostatic powder in the management of upper gastrointestinal malignant bleeding: a randomized controlled trial by Bruno Costa Martins, Andressa Abnader Machado, Rodrigo Corsato Scomparin, Gustavo Andrade Paulo, Adriana Safatle-Ribeiro, Sebastian Naschold Geiger, Luciano Lenz, Marcelo Simas Lima, Caterina Pennacchi, Ulysses Ribeiro, Alan N. Barkun, Fauze Maluf-Filho

“…Background and study aims Upper gastrointestinal bleeding (UGIB) from malignancy is associated with high rebleeding and mortality rates. …”
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