Showing 1 - 20 results of 477 for search '"vemurafenib"', query time: 0.23s Refine Results
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    Preparation and characterization of vemurafenib microemulsion by Mohammed Jassim Neamah, Entidhar J. Al-Akkam

    Published 2023-11-01
    “… Human melanoma is the most common and malignant type of skin cancer. Vemurafenib has been used for the treatment of malignant or metastatic melanoma. …”
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    Article
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    VEMURAFENIB IN TREATMENT OF MELANOMA WITH BRAIN METASTASES by D. R. Naskhletashvili, V. A. Gorbunova, A. Kh. Bekyashev, L. V. Demidov, G. Yu. Kharkevich, S. M. Banov, I. V. Samoylenko, K. А. Baryshnikov, K. V. Orlova, I. А. Utyashev, N. N. Petenko, I. G. Markina, E. A. Moskvina, S. V. Medvedev

    Published 2017-04-01
    “…According to the results of these studies vemurafenib can be recommended as a 1st line targeted drug for treatment of melanoma patients with BRAF V600 mutations and brain metastases. …”
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    RASopathic skin eruptions during vemurafenib therapy. by Jeannine D Rinderknecht, Simone M Goldinger, Sima Rozati, Jivko Kamarashev, Katrin Kerl, Lars E French, Reinhard Dummer, Benedetta Belloni

    Published 2013-01-01
    “…Vemurafenib is a potent inhibitor of V600 mutant BRAF with significant impact on progression-free and overall survival in advanced melanoma. …”
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    Article
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    Vemurafenib and cutaneous adverse events - report of five cases by Giselle de Barros Silva, Adriana Pessoa Mendes, Mariana Petaccia de Macedo, Clóvis Antônio Lopes Pinto, Ivana Lameiras Gibbons, João Pedreira Duprat Neto

    Published 2015-06-01
    “…AbstractVemurafenib is a selective inhibitor of V600E-mutant BRAF protein used to treat metastatic and unresectable melanoma. …”
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    Article
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    Insulin Reduces the Efficacy of Vemurafenib and Trametinib in Melanoma Cells by Osrodek M, Rozanski M, Czyz M

    Published 2020-08-01
    “…Changes induced by vemurafenib and trametinib in glutathione homeostasis and DNA repair gene expression were also attenuated by insulin. …”
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    Structure of the human protein kinase ZAK in complex with vemurafenib. by Mathea, S, Abdul Azeez, K, Salah, E, Tallant, C, Wolfreys, F, Konietzny, R, Fischer, R, Lou, H, Brennan, P, Schnapp, G, Pautsch, A, Kessler, B, Turk, B, Knapp, S

    Published 2016
    “…Here we report the first crystal structure of ZAK in complex with the B-RAF inhibitor vemurafenib. The co-crystal structure displayed a number of ZAK-specific features including a highly distorted P loop conformation enabling rational inhibitor design. …”
    Journal article
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    Orbital and chorioretinal manifestations of Erdheim-Chester disease treated with vemurafenib by Laura C. Huang, Katie L. Topping, Dita Gratzinger, Ryanne A. Brown, Beth A. Martin, Ruwan A. Silva, Andrea L. Kossler

    Published 2018-09-01
    “…Keywords: Histiocytosis, Vemurafenib, Orbital, Chorioretinal, Xanthomatous, Lipogranulomatous, BRAF…”
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