Conserved eukaryotic fusogens can fuse viral envelopes to cells. by Avinoam, O, Fridman, K, Valansi, C, Abutbul, I, Zeev-Ben-Mordehai, T, Maurer, U, Sapir, A, Danino, D, Grünewald, K, White, J, Podbilewicz, B

“…To study the structure and function of AFF-1, we constructed vesicular stomatitis virus (VSV) displaying AFF-1 on the viral envelope, substituting the native fusogen VSV glycoprotein. …”

Role of Viral Envelope Proteins in Determining Susceptibility of Viruses to IFITM Proteins by Thomas Marceau, Martine Braibant

“…While their general mechanism of inhibition seems to be non-specific, involving the tightening of membrane structures to prevent fusion between the viral envelope and cell membrane, numerous studies have underscored the importance of viral envelope proteins in determining the susceptibility of viruses to IFITMs. …”
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MARCH8 Targets Cytoplasmic Lysine Residues of Various Viral Envelope Glycoproteins by Yanzhao Zhang, Seiya Ozono, Takuya Tada, Minoru Tobiume, Masanori Kameoka, Satoshi Kishigami, Hideaki Fujita, Kenzo Tokunaga

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The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins by Kamel El Omari, Sai Li, Abhay Kotecha, Thomas S. Walter, Eduardo A. Bignon, Karl Harlos, Pentti Somerharju, Felix De Haas, Daniel K. Clare, Mika Molin, Felipe Hurtado, Mengqiu Li, Jonathan M. Grimes, Dennis H. Bamford, Nicole D. Tischler, Juha T. Huiskonen, David I. Stuart, Elina Roine

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Region-selective and site-specific glycation of influenza proteins surrounding the viral envelope membrane by Yi-Min She, Zongchao Jia, Xu Zhang

“…Topological analysis provides insights into the site-specific lysine glycation, localizing in the distinct structural regions of proteins surrounding the viral envelope membrane. Our finding highlights the proteome-wide discovery of lysine glycation of influenza membrane proteins and potential effects on the structural assembly, stability, receptor binding and enzyme activity, demonstrating that the impacts of accumulated glycation on the quality of products can be directly monitored by mass spectrometry-based structural proteomics analyses.…”
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The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins by El Omari, K, Li, S, Kotecha, A, Walter, T, Bignon, E, Harlos, K, Somerharju, P, De Haas, F, Clare, D, Molin, M, Hurtado, F, Li, M, Grimes, J, Bamford, D, Tischler, N, Huiskonen, J, Stuart, D, Roine, E

Averaging of viral envelope glycoprotein spikes from electron cryotomography reconstructions using Jsubtomo. by Huiskonen, J, Parsy, M, Li, S, Bitto, D, Renner, M, Bowden, T

Incorporation of CD55 into the Zika Viral Envelope Contributes to Its Stability against Human Complement by Zahra Malekshahi, Sarah Bernklau, Britta Schiela, Iris Koske, Zoltan Banki, Karin Stiasny, Claire L. Harris, Reinhard Würzner, Heribert Stoiber

“…By virus-capture assay and Western blots, the complement regulator protein CD55 was identified to be incorporated into the viral envelope. Blocking of CD55 by neutralizing Abs significantly increased the sensitivity to human complement. …”
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Viral Envelope Evolution in Simian–HIV-Infected Neonate and Adult-Dam Pairs of Rhesus Macaques by Elena E. Giorgi, Hui Li, Bhavna Hora, George M. Shaw, Kshitij Wagh, Wilton B. Williams

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Identification of Potential HCV Inhibitors Based on the Interaction of Epigallocatechin-3-Gallate with Viral Envelope Proteins by Fareena Shahid, Noreen, Roshan Ali, Syed Lal Badshah, Syed Babar Jamal, Riaz Ullah, Ahmed Bari, Hafiz Majid Mahmood, Muhammad Sohaib, Siddique Akber Ansari

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Oncolytic herpes simplex virus tumor targeting and neutralization escape by engineering viral envelope glycoproteins by Xiao-Qin Liu, Hong-Yi Xin, Yan-Ning Lyu, Zhao-Wu Ma, Xiao-Chun Peng, Ying Xiang, Ying-Ying Wang, Zi-Jun Wu, Jun-Ting Cheng, Jia-Fu Ji, Ji-Xin Zhong, Bo-Xu Ren, Xian-Wang Wang, Hong-Wu Xin

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A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope by Rutger D. Luteijn, Patrique Praest, Frank Thiele, Saravanan Manikam Sadasivam, Katrin Singethan, Jan W. Drijfhout, Christian Bach, Steffen Matthijn de Boer, Robert J. Lebbink, Sha Tao, Markus Helfer, Nina C. Bach, Ulrike Protzer, Ana I. Costa, J. Antoinette Killian, Ingo Drexler, Emmanuel J. H. J. Wiertz

“…The combined results strongly suggest that CPXV012 peptide inhibits virus infections by direct interactions with phosphatidylserine in the viral envelope. These results reiterate the potential of cationic peptides as broadly-acting virus inhibitors.…”
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Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1 by Nuttapong Kaewjiw, Thanawat Thaingtamtanha, Damini Mehra, Wanida Chawnawa, Tanapan Prommool, Chunya Puttikhunt, Adisak Songjaeng, Kessiri Kongmanas, Panisadee Avirutnan, Prasit Luangaram, Chatchawan Srisawat, Sittiruk Roytrakul, Stephan A. Bäurle, Sansanee Noisakran

“…Domperidone was identified by pharmacophore-based virtual screening as a small molecule that can bind to both the viral envelope (E) and the nonstructural protein 1 (NS1) of DENV. …”
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Molecular dissection of the assembly and morphogenesis processes of corona virus- the essential roles of the viral envelope protein. by Liu, Ding Xiang.

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Ethanol extract from Artemisia argyi leaves inhibits HSV-1 infection by destroying the viral envelope by Ping Liu, Lishan Zhong, Ji Xiao, Yuze Hu, Tao Liu, Zhe Ren, Yifei Wang, Kai Zheng

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Human immunoglobulins are transported to HCMV viral envelope by viral Fc gamma receptors-dependent and independent mechanisms by Giacomo Vezzani, Silvia Pimazzoni, Rossella Ferranti, Stefano Calò, Giuseppina Monda, Diego Amendola, Elisabetta Frigimelica, Domenico Maione, Mirko Cortese, Mirko Cortese, Marcello Merola, Marcello Merola

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Conservation of hydrophobicity within viral envelope glycoproteins reveals a putative hepatitis C virus fusion peptide by Taylor, A, O'Leary, J, Pollock, S, Zitzmann, N

Does the Cytoplasmic Tail Matter? Mechanism of Viral Envelope Glycoprotein Targeting by Membrane-Associated-RING-CH (MARCH) Proteins by Cheng man Lun, Abdul A. Waheed, Eric O. Freed

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Murine Trophoblast Stem Cells and Their Differentiated Cells Attenuate Zika Virus In Vitro by Reducing Glycosylation of the Viral Envelope Protein by Biswas Neupane, Mona Fendereski, Farzana Nazneen, Yan-Lin Guo, Fengwei Bai

“…We further show that the low infectivity of ZIKV propagated in TSCs and DTSCs is associated with a reduced level of glycosylation on the viral envelope (E) proteins, which are essential for ZIKV to establish initial attachment by binding to cell surface glycosaminoglycans (GAGs). …”
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Cyanovirin-N Binds Viral Envelope Proteins at the Low-Affinity Carbohydrate Binding Site without Direct Virus Neutralization Ability by Irene Maier, Robert H. Schiestl, Georg Kontaxis

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