Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin. by Brian B Gowen, Donald F Smee, Min-Hui Wong, Jeffery O Hall, Kie-Hoon Jung, Kevin W Bailey, John R Stevens, Yousuke Furuta, John D Morrey

“…A growing number of arenaviruses are known to cause viral hemorrhagic fever (HF), a severe and life-threatening syndrome characterized by fever, malaise, and increased vascular permeability. …”
Get full text

Ebola outbreak response; experience and development of screening tools for viral haemorrhagic fever (VHF) in a HIV center of excellence near to VHF epicentres. by Rosalind Parkes-Ratanshi, Ali Elbireer, Betty Mbambu, Faridah Mayanja, Alex Coutinho, Concepta Merry

“…INTRODUCTION: There have been 3 outbreaks of viral hemorrhagic fever (VHF) in Uganda in the last 2 years. …”
Get full text

The biosafety research road map: the search for evidence to support practices in human and veterinary laboratories by Blacksell, SD, Dhawan, S, Kusumoto, M, Le, KK, Summermatter, K, O'Keefe, J, Kozlovac, J, Almuhairi, SS, Sendow, I, Scheel, CM, Ahumibe, A, Masuku, ZM, Bennett, AM, Kojima, K, Harper, DR, Hamilton, K

“…Categories representing miscellaneous, respiratory, bioterrorism/zoonotic, and viral hemorrhagic fever pathogens were created within each group were selected for review. …”

Simulating Hunting Effects on the Wild Boar Population and African Swine Fever Expansion Using Agent-Based Modeling by Chanwoo Ko, Wonhee Cho, Byungmook Hwang, Byungwoo Chang, Wanmo Kang, Dongwook W. Ko

“…African swine fever (ASF) is a viral hemorrhagic fever fatal to animals of the Suidae family. …”
Get full text

Human and entomologic investigations of chikungunya outbreak in Mandera, Northeastern Kenya, 2016. by Samson Limbaso Konongoi, Albert Nyunja, Victor Ofula, Samuel Owaka, Hellen Koka, Edith Koskei, Fredrick Eyase, Daniel Langat, James Mancuso, Joel Lutomiah, Rosemary Sang

“…Patient blood samples were received at the Kenya Medical Research Institute (KEMRI) viral hemorrhagic fever laboratory and the immunoglobulin M enzyme linked immunosorbent assay (IgM ELISA) was used to test for the presence of IgM antibodies against chikungunya and dengue. …”
Get full text

Rift Valley fever seroprevalence and abortion frequency among livestock of Kisoro district, South Western Uganda (2016): a prerequisite for zoonotic infection by Ngabo Herbert Budasha, Jean-Paul Gonzalez, Tesfaalem Tekleghiorghis Sebhatu, Ezama Arnold

“…Abstract Background Rift Valley fever (RVF) is classified as viral hemorrhagic fever and is endemic in East and West Africa. …”
Get full text

Prevalence and risk factors of Lassa seropositivity in inhabitants of the forest region of Guinea: a cross-sectional study. by Solen Kernéis, Lamine Koivogui, N'Faly Magassouba, Kekoura Koulemou, Rosamund Lewis, Aristide Aplogan, Rebecca F Grais, Philippe J Guerin, Elisabeth Fichet-Calvet

“…BACKGROUND: Lassa fever is a viral hemorrhagic fever endemic in West Africa. The reservoir host of the virus is a multimammate rat, Mastomys natalensis. …”
Get full text

Big Epidemic of Small City: Crimean-Congo Hemorrhagic Fever by Ebru Doğan, Selcen Özer Kökkızıl, Mehtap Esen, Sümeyra Kayalı

“…Objective: Crimean-Congo hemorrhagic fever (CCHF) is the most common tick-borne viral hemorrhagic fever in our country and the world. While investigating the etiology of fever, tick contact should be questioned, especially in rural areas, and CCHF should be remembered. …”
Get full text

Development of single step RT-PCR for detection of Kyasanur forest disease virus from clinical samples by Gouri Chaubal, Prasad Sarkale, Pravin Kore, Pragya Yadav

“…This can be easily used in any BSL-2 laboratory for screening of KFD suspected cases or for differential diagnosis of viral hemorrhagic fever panel. Method: Three primer sets were designed and checked for sensitivity using known dilutions of KFD viral RNA (Ranging from 106 copies to 10 copies). …”
Get full text

Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog. by Brian B Gowen, Min-Hui Wong, Deanna Larson, Wei Ye, Kie-Hoon Jung, Eric J Sefing, Ramona Skirpstunas, Donald F Smee, John D Morrey, Stewart W Schneller

“…A growing number of arenaviruses can cause a devastating viral hemorrhagic fever (VHF) syndrome. They pose a public health threat as emerging viruses and because of their potential use as bioterror agents. …”
Get full text

Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus by Ming-Kai Jhan, Chia-Ling Chen, Ting-Jing Shen, Po-Chun Tseng, Yung-Ting Wang, Rahmat Dani Satria, Chia-Yi Yu, Chiou-Feng Lin

“…Infection with flaviviruses causes mild to severe diseases, including viral hemorrhagic fever, vascular shock syndrome, and viral encephalitis. …”
Get full text

Crimean Congo Hemorrhagic Fever Virus in Ticks Isolated from Ruminants in Jahrom, Fars Province, Southern Iran by Saman Rastgoo, Gholamreza Shokoohi, Hooshmand Ghorbaani Barnaaji, Ahmad Abolghazi

“…CCHF has been identified as the most frequent viral hemorrhagic fever in Iran. The route of CCHF transmission to humans is through infected tick bites, contact with infected livestock, infected blood or tissues of humans. …”
Get full text

A Loop Region in the N-Terminal Domain of Ebola Virus VP40 Is Important in Viral Assembly, Budding, and Egress by Emmanuel Adu-Gyamfi, Smita P. Soni, Clara S. Jee, Michelle A. Digman, Enrico Gratton, Robert V. Stahelin

“…Ebola virus (EBOV) causes viral hemorrhagic fever in humans and can have clinical fatality rates of ~60%. …”
Get full text

The Methanolic Extract of <i>Perilla frutescens</i> Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry by Yu-Ting Kuo, Ching-Hsuan Liu, Angela Corona, Elisa Fanunza, Enzo Tramontano, Liang-Tzung Lin

“…Ebola virus (EBOV), one of the most infectious human viruses and a leading cause of viral hemorrhagic fever, imposes a potential public health threat with several recent outbreaks. …”
Get full text

Prevalence and risk factors of Lassa seropositivity in inhabitants of the forest region of Guinea: a cross-sectional study by Kernéis, S, Koivogui, L, Magassouba, N, Koulemou, K, Lewis, R, Aplogan, A, Grais, R, Guerin, P, Fichet-Calvet, E

“…Background Lassa fever is a viral hemorrhagic fever endemic in West Africa. The reservoir host of the virus is a multimammate rat, Mastomys natalensis. …”

Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges) by John M. Dye, Kelly L. Warfield, Jay B. Wells, Robert C. Unfer, Sergey Shulenin, Hong Vu, Donald K. Nichols, M. Javad Aman, Sina Bavari

“…Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. …”
Get full text

Case report of a neonate with high viral SARSCoV-2 loads and long-term virus shedding by Monique A.L.J. Slaats, Maud Versteylen, Karin B. Gast, Bas B. Oude Munnink, Suzan D. Pas, Robbert G. Bentvelsen, Ron van Beek

Get full text

Alternative Treatment Method for Crimean Congo Hemorrhagic Fever: Coupled Plasma Filtration and Adsorption by Dilşat Tepe, Gürdal Yılmaz, Ahmet Oğuzhan Küçük, Mehtap Pehlivanlar Küçük

“…Crimean-Congo hemorrhagic fever (CCHF) is a viral hemorrhagic fever syndrome that can cause multi-organ failure with hyperactivation of the immune system. …”
Get full text

Role of <it>Culex </it>and <it>Anopheles </it>mosquito species as potential vectors of rift valley fever virus in Sudan outbreak, 2007 by Galal Fatma H, Seufi AlaaEddeen M

“…Case management related interventions; health education and vector control efforts are extremely effective in preparedness for viral hemorrhagic fever and other seasonal outbreaks.</p>…”
Get full text

Lassa Virus Circulation in Small Mammal Populations in Bo District, Sierra Leone by Umaru Bangura, Jacob Buanie, Joyce Lamin, Christopher Davis, Gédéon Ngiala Bongo, Michael Dawson, Rashid Ansumana, Dianah Sondufu, Emma C. Thomson, Foday Sahr, Elisabeth Fichet-Calvet

“…Lassa fever is a viral hemorrhagic fever caused by the Lassa virus LASV, which was first isolated in the rodent <i>Mastomys natalensis</i> in 1974 in Kenema, Sierra Leone. …”
Get full text