Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome by Jeong Rae Yoo, Sun Hyung Kim, Young Ree Kim, Keun Hwa Lee, Won Sup Oh, Sang Taek Heo

“…Background/Aims Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not been established. …”
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Aptamer-based diagnosis of various SARS-CoV2 strains isolated from clinical specimens by Zahra Sadat Moshref, Tahmineh Jalali, Razieh Rezaei Adriani, Elahe Soltati, Seyed Latif Mousavi Gargari

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Design, Synthesis, and Biological Evaluation of Benzimidazole Derivatives as Potential Lassa Virus Inhibitors by Jinwei Chen, Likun Xu, Baogang Wang, Dongna Zhang, Liangliang Zhao, Zhuchun Bei, Yabin Song

“…The Lassa virus (LASV) causes Lassa fever, a highly infectious and lethal agent of acute viral hemorrhagic fever. At present, there are still no effective treatments available, creating an urgent need to develop novel therapeutics. …”
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Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus by Robin D.V. Kleinert, Eduardo Montoya-Diaz, Tanvi Khera, Kathrin Welsch, Birthe Tegtmeyer, Sebastian Hoehl, Sandra Ciesek, Richard J.P. Brown

“…Sporadic outbreaks of YFV occur in endemic tropical regions, causing a viral hemorrhagic fever (VHF) associated with high mortality rates. …”
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In silico formulation of a next-generation multiepitope vaccine for use as a prophylactic candidate against Crimean-Congo hemorrhagic fever by Rahat Alam, Abdus Samad, Foysal Ahammad, Suza Mohammad Nur, Ahad Amer Alsaiari, Raihan Rahman Imon, Md. Enamul Kabir Talukder, Zulkar Nain, Md. Mashiar Rahman, Farhan Mohammad, Tomasz M. Karpiński

“…The virus is responsible for severe viral hemorrhagic fever outbreaks, with a case fatality rate of up to 40%. …”
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Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4 by Chih-Yun Lai, Daniel P. Strange, Teri Ann S. Wong, Axel T. Lehrer, Saguna Verma

“…Ebola virus (EBOV), a member of the Filoviridae family, causes the most severe form of viral hemorrhagic fever. Although no FDA licensed vaccine or treatment against Ebola virus disease (EVD) is currently available, Ebola virus glycoprotein (GP) is the major antigen used in all candidate Ebola vaccines. …”
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Crimean-Congo Hemorrhagic Fever in Differential Diagnosis During the Coronavirus Disease-2019 Pandemic by Ayşe Sağmak Tartar, Ayhan Akbulut, Kutbeddin Demirdağ, Şafak Özer Balin

“…Objective:Crimean-Congo Hemorrhagic Fever (CCHF) is a disease of the viral hemorrhagic fever group and is endemic in certain regions in Turkey. …”
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The Origins and Future of Sentinel: An Early-Warning System for Pandemic Preemption and Response by Yolanda Botti-Lodovico, Parvathy Nair, Dolo Nosamiefan, Matthew Stremlau, Stephen Schaffner, Sebastian V. Agignoae, John Oke Aiyepada, Fehintola V. Ajogbasile, George O. Akpede, Foday Alhasan, Kristian G. Andersen, Danny A. Asogun, Oladele Oluwafemi Ayodeji, Aida S. Badiane, Kayla Barnes, Matthew R. Bauer, Antoinette Bell-Kareem, Muoebonam Ekene Benard, Ebo Ohomoime Benevolence, Osiemi Blessing, Chloe K. Boehm, Matthew L. Boisen, Nell G. Bond, Luis M. Branco, Michael J. Butts, Amber Carter, Andres Colubri, Awa B. Deme, Katherine C. DeRuff, Younousse Diédhiou, Akhilomen Patience Edamhande, Siham Elhamoumi, Emily J. Engel, Philomena Eromon, Mosoka Fallah, Onikepe A. Folarin, Ben Fry, Robert Garry, Amy Gaye, Michael Gbakie, Sahr M. Gevao, Gabrielle Gionet, Adrianne Gladden-Young, Augustine Goba, Jules Francois Gomis, Anise N. Happi, Mary Houghton, Chikwe Ihekwuazu, Christopher Ojemiega Iruolagbe, Jonathan Jackson, Simbirie Jalloh, Jeremy Johnson, Lansana Kanneh, Adeyemi Kayode, Molly Kemball, Ojide Chiedozie Kingsley, Veronica Koroma, Dylan Kotliar, Samar Mehta, Hayden C. Metsky, Airende Michael, Marzieh Ezzaty Mirhashemi, Kayvon Modjarrad, Mambu Momoh, Cameron A. Myhrvold, Okonofua Grace Naregose, Tolla Ndiaye, Mouhamadou Ndiaye, Aliou Ndiaye, Erica Normandin, Ikponmwosa Odia, Judith Uche Oguzie, Sylvanus A. Okogbenin, Peter O. Okokhere, Johnson Okolie, Idowu B. Olawoye, Testimony J. Olumade, Paul E. Oluniyi, Omigie Omoregie, Daniel J. Park, Mariétou Faye Paye, Brittany Petros, Anthony A. Philippakis, Abechi Priscilla, Alan Ricks, Anne Rimoin, John Demby Sandi, John S. Schieffelin, Monica Schreiber, Mame Cheikh Seck, Sameed Siddiqui, Katherine Siddle, Allison R. Smither, Mouhamad Sy, Ngayo Sy, Christopher H. Tomkins-Tinch, Oyewale Tomori, Chinedu Ugwu, Jessica N. Uwanibe, Eghosasere Anthonia Uyigue, Dada Ireti Victoria, Anika Vinzé, Megan E. Vodzak, Nicole Welch, Haja Isatta Wurie, Daba Zoumarou, Donald S. Grant, Daouda Ndiaye, Bronwyn MacInnis, Pardis C. Sabeti, Christian Happi

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Challenges and Opportunities in Lassa fever Control Efforts in Nigeria by Anise N. Happi, Chinedu A. Ugwu, Kazeem Akano, Christian T. Happi

“…Lassa fever (LF) is a serious viral hemorrhagic fever endemic in West Africa. The history of Lassa fever virus (LVS) in Nigeria is that of neglect, wickedness and apathy (Akpede et al., 2018). …”
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Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions by Seif S. Al-Abri, Idris Al Abaidani, Mehdi Fazlalipour, Ehsan Mostafavi, Hakan Leblebicioglu, Natalia Pshenichnaya, Ziad A. Memish, Roger Hewson, Eskild Petersen, Peter Mala, Tran Minh Nhu Nguyen, Mamunur Rahman Malik, Pierre Formenty, Rosanna Jeffries

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CD8+ T-cells target the Crimean-Congo haemorrhagic fever virus Gc protein to control the infection in wild-type miceResearch in context by Deepashri Rao, Kimberly Meade-White, Shanna Leventhal, Evan Mihalakakos, Aaron Carmody, Heinz Feldmann, David W. Hawman

“…Summary: Background: Crimean-Congo haemorrhagic fever (CCHF) is a serious viral hemorrhagic fever caused by the CCHF virus (CCHFV). …”
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Molecular diagnostics for lassa fever at Irrua specialist teaching hospital, Nigeria: lessons learnt from two years of laboratory operation. by Danny A Asogun, Donatus I Adomeh, Jacqueline Ehimuan, Ikponmwonsa Odia, Meike Hass, Martin Gabriel, Stephan Olschläger, Beate Becker-Ziaja, Onikepe Folarin, Eric Phelan, Philomena E Ehiane, Veritas E Ifeh, Eghosasere A Uyigue, Yemisi T Oladapo, Ekene B Muoebonam, Osagie Osunde, Andrew Dongo, Peter O Okokhere, Sylvanus A Okogbenin, Mojeed Momoh, Sylvester O Alikah, Odigie C Akhuemokhan, Peter Imomeh, Maxy A C Odike, Stephen Gire, Kristian Andersen, Pardis C Sabeti, Christian T Happi, George O Akpede, Stephan Günther

“…BACKGROUND: Lassa fever is a viral hemorrhagic fever endemic in West Africa. However, none of the hospitals in the endemic areas of Nigeria has the capacity to perform Lassa virus diagnostics. …”
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Optimal reference genes for RNA tissue analysis in small animal models of hemorrhagic fever viruses by Katherine A. Davies, Stephen R. Welch, Teresa E. Sorvillo, JoAnn D. Coleman-McCray, María Laura Martin, Julia M. Brignone, Joel M. Montgomery, Christina F. Spiropoulou, Jessica R. Spengler

“…Here, we investigated the suitability of nine potential RGs in laboratory animals commonly used to study viral hemorrhagic fever infection. Using tissues (liver, spleen, gonad [ovary or testis], kidney, heart, lung, eye, brain, and blood) collected from naïve animals and those infected with Crimean–Congo hemorrhagic fever (mice), Nipah (hamsters), or Lassa (guinea pigs) viruses, optimal species-specific RGs were identified based on five web-based algorithms to assess RG stability. …”
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Lassa fever-induced hearing loss: The neglected disability of hemorrhagic fever by Samuel C. Ficenec, Jeffrey Percak, Sara Arguello, Alison Bays, Augustine Goba, Michael Gbakie, Jeffrey G. Shaffer, Susan D. Emmett, John S. Schieffelin, Daniel Bausch

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Establishment of pseudovirus infection mouse models for in vivo pharmacodynamics evaluation of filovirus entry inhibitors by Qing Chen, Ke Tang, Xiaoyu Zhang, Panpan Chen, Ying Guo

“…Filoviruses cause severe and fatal viral hemorrhagic fever in humans. Filovirus research has been extensive since the 2014 Ebola outbreak. …”
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Immunity against <i>Lagovirus europaeus</i> and the Impact of the Immunological Studies on Vaccination by Claudia Müller, Rafał Hrynkiewicz, Dominika Bębnowska, Jaime Maldonado, Massimiliano Baratelli, Bernd Köllner, Paulina Niedźwiedzka-Rystwej

“…In the early 1980s, a highly contagious viral hemorrhagic fever in rabbits (<i>Oryctolagus cuniculus</i>) emerged, causing a very high rate of mortality in these animals. …”
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Spatial risk analysis for the introduction and circulation of six arboviruses in the Netherlands by Helen Joan Esser, Yorick Liefting, Adolfo Ibáñez-Justicia, Henk van der Jeugd, Chris A. M. van Turnhout, Arjan Stroo, Chantal B. E. M. Reusken, Marion P. G. Koopmans, Willem Fred de Boer

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The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression by Lisa Wendt, Janine Brandt, Bianca S. Bodmer, Sven Reiche, Marie Luisa Schmidt, Shelby Traeger, Thomas Hoenen

“…Ebola virus (EBOV) causes severe outbreaks of viral hemorrhagic fever in humans. While virus-host interactions are promising targets for antivirals, there is only limited knowledge regarding the interactions of EBOV with cellular host factors. …”
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Characterization of Yellow Fever Suspected Cases and Confirmed Outbreaks in a Southwest State, Nigeria, 2021 by Itse Olaoye, Akinola Fatiregun, Adewale M. Adejugbagbe, Modupeola Dosumu, Ekun Opeyemi, Zubairu Mahmud, David Adeleke, Tsemaye Jacdonmi, Aladesawe Adesokeji, Famokun Gboyega, Abiona Samuel

“…Background: Yellow fever (YF) is an acute viral hemorrhagic fever caused by the yellow fever virus and transmitted by Aedes mosquito species. …”
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Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 [version 1; peer review: 2 approved] by Áine O'Toole, Verity Hill, Oliver G. Pybus, Alexander Watts, Issac I. Bogoch, Kamran Khan, Jane P. Messina, The COVID-19 Genomics UK (COG-UK) consortium, Network for Genomic Surveillance in South Africa (NGS-SA), Brazil-UK CADDE Genomic Network, Houriiyah Tegally, Richard R. Lessells, Jennifer Giandhari, Sureshnee Pillay, Kefentse Arnold Tumedi, Gape Nyepetsi, Malebogo Kebabonye, Maitshwarelo Matsheka, Madisa Mine, Sima Tokajian, Hamad Hassan, Tamara Salloum, Georgi Merhi, Jad Koweyes, Jemma L. Geoghegan, Joep de Ligt, Xiaoyun Ren, Matthew Storey, Nikki E. Freed, Chitra Pattabiraman, Pramada Prasad, Anita S. Desai, Ravi Vasanthapuram, Thomas F. Schulz, Lars Steinbrück, Tanja Stadler, Swiss Viollier Sequencing Consortium, Antonio Parisi, Angelica Bianco, Darío García de Viedma, Sergio Buenestado-Serrano, Vítor Borges, Joana Isidro, Sílvia Duarte, João Paulo Gomes, Neta S. Zuckerman, Michal Mandelboim, Orna Mor, Torsten Seemann, Alicia Arnott, Jenny Draper, Mailie Gall, William Rawlinson, Ira Deveson, Sanmarié Schlebusch, Jamie McMahon, Lex Leong, Chuan Kok Lim, Maria Chironna, Daniela Loconsole, Antonin Bal, Laurence Josset, Edward Holmes, Kirsten St. George, Erica Lasek-Nesselquist, Reina S. Sikkema, Bas Oude Munnink, Marion Koopmans, Mia Brytting, V. Sudha rani, S. Pavani, Teemu Smura, Albert Heim, Satu Kurkela, Massab Umair, Muhammad Salman, Barbara Bartolini, Martina Rueca, Christian Drosten, Thorsten Wolff, Olin Silander, Dirk Eggink, Chantal Reusken, Harry Vennema, Aekyung Park, Christine Carrington, Nikita Sahadeo, Michael Carr, Gabo Gonzalez, SEARCH Alliance San Diego, National Virus Reference Laboratory, SeqCOVID-Spain, Danish Covid-19 Genome Consortium (DCGC), Communicable Diseases Genomic Network (CDGN), Dutch National SARS-CoV-2 surveillance program, Division of Emerging Infectious Diseases (KDCA), Tulio de Oliveira, Nuno Faria, Andrew Rambaut, Moritz U. G. Kraemer

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