First laboratory confirmation and sequencing of Zaire ebolavirus in Uganda following two independent introductions of cases from the 10th Ebola Outbreak in the Democratic Republic... by Luke Nyakarahuka, Sophia Mulei, Shannon Whitmer, Kyondo Jackson, Alex Tumusiime, Amy Schuh, Jimmy Baluku, Allison Joyce, Felix Ocom, Jayne B Tusiime, Joel M Montgomery, Stephen Balinandi, Julius J Lutwama, John D Klena, Trevor R Shoemaker, ‘Kasese EVD Outbreak Response Team’

“…Uganda established a domestic Viral Hemorrhagic Fever (VHF) testing capacity in 2010 in response to the increasing occurrence of filovirus outbreaks. …”
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A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct Lassa viruses. by David Safronetz, Chad Mire, Kyle Rosenke, Friederike Feldmann, Elaine Haddock, Thomas Geisbert, Heinz Feldmann

“…Additionally, this work highlights the need for the further development of disease models for geographical distinct LASV strains, particularly those from Nigeria, in order to comprehensively evaluate potential vaccines and therapies against this prominent agent of viral hemorrhagic fever.…”
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Comparative study between Ribavirin and Ribavirin plus Intravenous Immunoglobulin against Crimean Congo hemorrhagic fever by Hassan Salehi, Marzieh Salehi, Neda Adibi, Maryam Salehi

“…Conclusion: Considering our results, using IVIG in viral hemorrhagic fever (VHF) may need further evaluations.…”
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Mathematical analysis of Lassa fever epidemic with effects of environmental transmission by Abdurrahman Abdulhamid, Nafiu Hussaini, Salihu S. Musa, Daihai He

“…Lassa fever (LF) is a viral hemorrhagic fever transmitted predominantly by rodents vector. …”
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Determination of serum adenosine deaminase and xanthine oxidase levels in patients with crimean-congo hemorrhagic fever by V. Kenan Celik, Ismail Sari, Aynur Engin, Yildiz Gürsel, Hüseyin Aydin, Sevtap Bakir

“…OBJECTIVE: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo hemorrhagic fever. …”
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Neuropathology of yellow fever autopsy cases by Fernando Pereira Frassetto, Sergio Rosemberg

“…Abstract Background Yellow fever is a viral hemorrhagic fever caused by yellow fever virus, a mosquito-borne flavivirus. …”
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Hantavirus-Driven PD-L1/PD-L2 Upregulation: An Imperfect Viral Immune Evasion Mechanism by Martin J. Raftery, Mohammed O. Abdelaziz, Jörg Hofmann, Günther Schönrich

“…Hantaviruses cause viral hemorrhagic fever (VHF) which is associated with strong immune activation resulting in vigorous CD8+ T cell responses. …”
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Therapeutic effects of favipiravir against severe fever with thrombocytopenia syndrome virus infection in a lethal mouse model: Dose-efficacy studies upon oral administration. by Hideki Tani, Takashi Komeno, Aiko Fukuma, Shuetsu Fukushi, Satoshi Taniguchi, Masayuki Shimojima, Akihiko Uda, Shigeru Morikawa, Nozomi Nakajima, Yousuke Furuta, Masayuki Saijo

“…Severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV), is a viral hemorrhagic fever with a high case fatality rate. Favipiravir was reported to be effective in the treatment of SFTSV infection in vivo in type I interferon receptor knockout (IFNAR-/-) mice at treatment dosages of both 60 mg/kg/day and 300 mg/kg/day for a duration of 5 days. …”
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Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages. by Allison Groseth, Thomas Hoenen, Michaela Weber, Svenja Wolff, Astrid Herwig, Andreas Kaufmann, Stephan Becker

“…Surprisingly, JUNV infection did not have an effect on any of the cytokines examined indicating that, in contrast to other viral hemorrhagic fever viruses, macrophage-derived cytokine production is unlikely to play an active role in contributing to the cytokine dysregulation observed in JUNV infected patients. …”
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Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. by Michelle Mendenhall, Andrew Russell, Donald F Smee, Jeffery O Hall, Ramona Skirpstunas, Yousuke Furuta, Brian B Gowen

“…Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic fever syndromes Lassa fever and Argentine hemorrhagic fever, respectively. …”
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Rift Valley fever virus outbreak in Mauritania yet again in 2022: No room for complacency by Shehroze Tabassum, Farhan Naeem, Masood Azhar, Aroma Naeem, Malik O. Oduoye, Tirth Dave

“…Abstract Rift Valley fever is an important yet ignored viral hemorrhagic fever claiming many lives of African and Arabian countries over the past decade. …”
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On revealing the gene targets of Ebola virus microRNAs involved in the human skin microbiome by Pei-Chun Hsu, Bin-Hao Chiou, Chun-Ming Huang

“…Ebola virus, a negative-sense single-stranded RNA virus, causes severe viral hemorrhagic fever and has a high mortality rate. Histopathological and immunopathological analyses of Ebola virus have revealed that histopathological changes in skin tissue are associated with various degrees of endothelial cell swelling and necrosis. …”
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Genetic characterization of Lassa virus strains isolated from 2012 to 2016 in southeastern Nigeria. by Olamide K Oloniniyi, Uche S Unigwe, Sayaka Okada, Mayuko Kimura, Shota Koyano, Yukiko Miyazaki, Michael O Iroezindu, Nnenna A Ajayi, Chinedu M Chukwubike, Nneka M Chika-Igwenyi, Anne C Ndu, Damian U Nwidi, Haruka Abe, Shuzo Urata, Yohei Kurosaki, Jiro Yasuda

“…Lassa virus (LASV) is endemic in parts of West Africa where it causes Lassa fever (LF), a viral hemorrhagic fever with frequent fatal outcomes. The diverse LASV strains are grouped into six major lineages based on the geographical location of the isolated strains. …”
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High genetic diversity and adaptive potential of two simian hemorrhagic fever viruses in a wild primate population. by Adam L Bailey, Michael Lauck, Andrea Weiler, Samuel D Sibley, Jorge M Dinis, Zachary Bergman, Chase W Nelson, Michael Correll, Michael Gleicher, David Hyeroba, Alex Tumukunde, Geoffrey Weny, Colin Chapman, Jens H Kuhn, Austin L Hughes, Thomas C Friedrich, Tony L Goldberg, David H O'Connor

“…Nearly nothing is known about the biological properties of SHFVs in nature, although the SHFV type strain, SHFV-LVR, has caused devastating outbreaks of viral hemorrhagic fever in captive macaques. Here we detected SHFV-krc1 and SHFV-krc2 in 40% and 47% of 60 wild red colobus tested, respectively. …”
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The potential epidemic threat of Ebola virus and the development of a preventive vaccine by Hong-Qing Zhang, Qiu-Yan Zhang, Zhi-Ming Yuan, Bo Zhang

“…Ebola virus (EBOV) is classified as a category A pathogen as it causes viral hemorrhagic fever, one of the most-deadly virus-related diseases. …”
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Assessment of Knowledge and Sources of Information on Lassa Fever Infection Among the Undergraduate Students of Ebonyi State University, Nigeria by MaryJoy Umoke, Prince Christian Ifeanachor Umoke, Chioma Adaora Nwalieji, Rosemary N. Onwe, Ifeanyi Emmanuel Nwafor, Samson Olaoluwa Agbaje, Ignatius O. Nwimo

“…Lassa fever is a zoonotic disease characterized by acute viral hemorrhagic fever, endemic in West Africa including Nigeria. …”
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Use of recombinant adenovirus vectored consensus IFN-α to avert severe arenavirus infection. by Brian B Gowen, Jane Ennis, Andrew Russell, Eric J Sefing, Min-Hui Wong, Jeffrey Turner

“…Several arenaviruses can cause viral hemorrhagic fever, a severe disease with case-fatality rates in hospitalized individuals ranging from 15-30%. …”
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Prognostic Significance of Antithrombin Activity in Patients with Crimean-Congo Hemorrhagic Fever by Mustafa Usanmaz, Ilhami Kiki, Kemalettin Ozden, Zulal Ozkurt

“…Objective: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral hemorrhagic fever. Disseminated intravascular coagulation (DIC) is an important complication of this disease, especially in severe and fatal cases. …”
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Developing Vaccines to Improve Preparedness for Filovirus Outbreaks: The Perspective of the USA Biomedical Advanced Research and Development Authority (BARDA) by Lindsay A. Parish, Eric J. Stavale, Christopher R. Houchens, Daniel N. Wolfe

“…Outbreaks of viral hemorrhagic fever caused by filoviruses have become more prevalent in recent years, with outbreaks of Ebola virus (EBOV), Sudan virus (SUDV), and Marburg virus (MARV) all occurring in 2022 and 2023. …”
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Building diagnostic systems in Sierra Leone: The role of point-of-care devices in laboratory strengthening by Rashid Ansumana, Fatmata Bah, Kan Biao, Doris Harding, Mohamed B. Jalloh, Ann H. Kelly, Francess Koker, Zikan Koroma, Mambu Momoh, Mohamed H. Rogers, James Rogers, Alice Street, Eva Vernooij, Isatta Wurie

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