Evaluation of COVID-19 risk in patients on systemic retinoid therapy by Emine Müge Acar, Kemal Özyurt, Rukiye Akyol

“…Patients who presented to the dermatology clinic for various skin diseases, such as eczema, vitiligo, tinea, etc., who were not on systemic retinoid therapy, and who received topical medications comprised the control group. …”
Get full text

Pattern changes of cutaneous dermatoses among Iraqi women preceding and during the COVID-19 pandemic [version 3; peer review: 2 approved] by Galawish A. Abdullah

“…Acne vulgaris, rosacea, lichen planus, urticaria, pityriasis rosea, seborrheic dermatitis, and vitiligo were increased, but psoriasis, alopecia areata, other types of dermatitis, and melasma were reduced but none to a significant level. …”
Get full text

Cosmetic Applications of Bee Venom by Aida A. Abd El-Wahed, Shaden A. M. Khalifa, Mohamed H. Elashal, Syed G. Musharraf, Aamer Saeed, Alfi Khatib, Haroon Elrasheid Tahir, Xiaobo Zou, Yahya Al Naggar, Arshad Mehmood, Kai Wang, Hesham R. El-Seedi

“…Nowadays, BV is applied to combat several skin diseases, such as atopic dermatitis, acne vulgaris, alopecia, vitiligo, and psoriasis. BV is used extensively in topical preparations as cosmetics and used as dressing for wound healing, as well as in facemasks. …”
Get full text

Case report: A rare case of immunotherapy induced isolated left CN VI palsy in a patient with unresectable melanoma by Samantha Su Ping Low, Karim El-Shakankery, Ewan Brown, Alan Christie, Sally McCormack, Mark Stares, Mark Stares

“…She also experienced Grade 3 dermatitis requiring topical steroids, Grade 2 hypothyroidism and vitiligo. She continues to have an excellent clinical and radiological response, despite further immunotherapy being suspended.ConclusionThis is the first reported UK case of immunotherapy-induced isolated cranial nerve VI palsy. …”
Get full text

In situ-formed cryomicroneedles for intradermal cell delivery by Mengjia Zheng, Tianli Hu, Yating Yang, Xuan Qie, Huaxin Yang, Yuyue Zhang, Qizheng Zhang, Ken-Tye Yong, Wei Liu, Chenjie Xu

“…As a proof-of-concept, we examined the loading and intradermal delivery of three cell types in clinically relevant in vitro and in vivo models, including mesenchymal stem cells for wound healing, melanocytes for vitiligo treatment, and antigen-pulsed dendritic cells for cancer vaccination.…”
Get full text

Skin Manifestations in Patients with Selective Immunoglobulin E Deficiency by César Picado, Adriana P. García-Herrera, José Hernández-Rodríguez, Alexandru Vlagea, Mariona Pascal, Joan Bartra, José Manuel Mascaró

“…Fifteen patients (60%) had different types of associated autoimmune diseases, Hashimoto’s thyroiditis being the most frequent (<i>n</i> = 5, 20%), followed by arthritis (<i>n</i> = 4, 16%), autoimmune hepatitis, neutropenia, vitiligo, and Sjögren’s syndrome (<i>n</i> = 2, 8% each). …”
Get full text

Synthesis and evaluation of coumarin derivatives on antioxidative, tyrosinase inhibitory activities, melanogenesis, and in silico investigations by Kasemsiri Chandarajoti, Jiraporn Kara, Paptawan Suwanhom, Teerapat Nualnoi, Jindaporn Puripattanavong, Vannajan Sanghiran Lee, Varomyalin Tipmanee, Luelak Lomlim

“…Based on the findings, compound 13 and 14 offer potential for development as skin-lightening agents and vitiligo therapy agents, respectively.…”
Get full text

Common Dermatologic Disorders in Down Syndrome: Systematic Review by Megan Lam, Justin Di Lu, Levi Elhadad, Cathryn Sibbald, Raed Alhusayen

“…The most common dermatologic conditions reported includes atopic dermatitis (8 studies, n=180; 19.7% mean prevalence), hidradenitis suppurativa (15, n=478; 3.2%), ichthyosis (4, n=16; 4.7%), lichen nitidus (6, n=6; 1.1%), psoriasis (21, n=65; 4.8%), alopecia areata (27, n=253; 7.4%), vitiligo (8, n=40; 4.4%), onychomycosis (3, n=198; 24.7%), calcinosis cutis (14, n=15), connective tissue nevi (6, n=6), dermatofibroma (3, n=3), melanoma (3, n=3), syringomas (14, n=182; 21.2%), and elastosis perforans serpiginosa (19, n=24; 0.5%). …”
Get full text

Single Radiotherapy Fraction with Local Anti-CD40 Therapy Generates Effective Abscopal Responses in Mouse Models of Cervical Cancer by Jana Wood, Sayeda Yasmin-Karim, Romy Mueller, Akila N. Viswanathan, Wilfred Ngwa

“…Moreover, re-challenged responders to the treatment developed vitiligo, suggesting developed immune memory for this cancer. …”
Get full text

Case Report: An early-onset inflammatory colitis due to a variant in TNFAIP3 causing A20 haploinsufficiency by Laura Zanatta, Francesca Biscaro, Silvia Bresolin, Maurizio Marzaro, Samantha Sarcognato, Ivana Cataldo, Antonio Marzollo, Stefano Martelossi

“…The same TNFAIP3 variant was also found in her father who had suffered from recurrent oral aphthosis, vitiligo and thyroiditis since childhood. In conclusion, we described a young patient with a novel heterozygous mutation in TNFAIP3 who developed BD-like symptoms. …”
Get full text

A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics by Rochi Saurabh, Césaire J. K. Fouodo, Inke R. König, Hauke Busch, Inken Wohlers

“…These are systemic (systemic lupus erythematosus) as well as organ-specific, affecting the gastrointestinal tract (inflammatory bowel disease as well as specifically Crohn’s disease and ulcerative colitis), joints (juvenile ideopathic arthritis, psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis), glands (Sjögren syndrome), the nervous system (multiple sclerosis), and the skin (vitiligo).…”
Get full text

Population pharmacokinetic modeling of oral brepocitinib in healthy volunteers and patients with immuno‐inflammatory diseases by Farzaneh Maleki, Elias Clark, Christopher Banfield, Wonkyung Byon, Timothy Nicholas

“…Blood samples from phase I HV and phase II clinical studies of patients with alopecia areata, psoriasis, psoriatic arthritis, ulcerative colitis (UC), vitiligo, and hidradenitis suppurativa were analyzed using a nonlinear mixed‐effects modeling approach. …”
Get full text

A fragment of type VI collagen alpha-6 chain is elevated in serum from patients with atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus and melano... by Signe Holm Nielsen, Helena Port, Cecilie Møller Hausgaard, Jesper Grønlund Holm, Jacob P. Thyssen, Solveig Skovlund Groen, Morten Karsdal, Valdemar Wendelboe Nielsen, Alexander Egeberg, Anne-Christine Bay-Jensen, Simon Francis Thomsen

“…The aim of this study was to develop and validate a competitive ELISA, targeting the N-terminal of COL6-α6-chain, named C6A6, and evaluate its associations with the dermatological condition’s atopic dermatitis, psoriasis, hidradenitis suppurativa, systemic lupus erythematosus, systemic sclerosis, urticaria, vitiligo, and cutaneous malignant melanoma in comparison, to healthy controls. …”
Get full text

KUVA (khellin plus ultraviolet A) stimulates proliferation and melanogenesis in normal human melanocytes and melanoma cells in vitro. by Carlie, G, Ntusi, N, Hulley, P, Kidson, S

“…BACKGROUND: Khellin is a naturally occurring furochromone which, when combined with artificial ultraviolet (UV) A or solar irradiation (KUVA), is reported to repigment vitiligo skin as effectively as PUVA photochemotherapy. …”

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells. by Mackensen, A, Herbst, B, Chen, J, Köhler, G, Noppen, C, Herr, W, Spagnoli, G, Cerundolo, V, Lindemann, A

“…Clinical and immunological responses consisted of anti-tumor responses in 2 patients, increased melanoma peptide-specific delayed-type hypersensitivity reactions in 4 patients, significant expansion of Melan-A- and gp100-specific cytotoxic T lymphocytes in the peripheral blood lymphocytes of 1 patient after vaccination and development of vitiligo in another HLA-A2(+) patient. Our data indicate that the vaccination of peptide-pulsed DCs is capable of inducing clinical and systemic tumor-specific immune responses without provoking major side effects.…”

نوعيّة الحياة عند مرضى البهاق وعلاقتها بالمتغيّرات المتنوّعة by عبد الله الخير, ندى بلبل

“…Our survey included 73 vitiligo patients. Diagnosis was established based upon clinical signs. …”
Get full text

The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review by Federico Diotallevi, Anna Campanati, Emanuela Martina, Giulia Radi, Matteo Paolinelli, Andrea Marani, Elisa Molinelli, Matteo Candelora, Marina Taus, Tiziana Galeazzi, Albano Nicolai, Annamaria Offidani

“…It is therefore important for dermatologists to be aware about the scientific basis linking nutrition to inflammatory skin diseases such as psoriasis, atopic dermatitis, hidradenitis suppurativa, bullous diseases, vitiligo, and alopecia areata, and whether changes in diet can influence the clinical course of these diseases. …”
Get full text

IgA Vasculitis and C3 Glomerulonephritis: One Patient... Various Autoimmune Diseases by Ana Margarida Pedro Antunes Ferreira Gaudêncio, Ana Catarina Lameiras, Teresa Mendonça

“…The authors present a case of a 50-year-old woman diagnosed with vitiligo ad immune thrombocytopenic purpura (ITP). …”
Get full text

Diagnóstico precoce da hanseníase: identificação de lesão cutânea inicial pela população de região metropolitana do Rio de Janeiro. by Renata Antunes Joffe, Maria Leide Wand-Del-Rey Oliveira, Fernanda C.L. Rueda, Mônica Cunha Duarte, Karen H. Americano, Aline S. Pichone

“…Ao longo de 2002, foram entrevistadas 800 mulheres, e apresentadas quatro imagens de lesões cutâneas (vitiligo, hanseníase indeterminada, mal perfurante plantar e hanseníase dimorfa) visando a sua impressão diagnóstica. …”
Get full text

Modified Non-Cultured Cell Spray Induced Epithelization in LAMB3 Mutation Epidermolysis Bullosa by Widhiati S, Dewi ST, Yefta, Danarti R, Soebono H, Irmawati YE, Puspitasari M, Trisnowati N, Wibawa T, Purnomosari D, Wirohadidjojo YW

“…Suci Widhiati,1,2 Shinta Trilaksmi Dewi,3 Yefta,3 Retno Danarti,3 Hardyanto Soebono,3 Yulia Eka Irmawati,3 Monika Puspitasari,3 Niken Trisnowati,3 Tri Wibawa,4 Dewajani Purnomosari,5 Yohanes Widodo Wirohadidjojo3 1Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia; 2Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; 3Department of Dermatology and Venereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; 4Department of Microbiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; 5Department of Histology and Cell Biology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, IndonesiaCorrespondence: Yohanes Widodo Wirohadidjojo, Department of Dermatology and Venereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Gedung Radiopoetro, lt. 3 Sekip, Yogyakarta, 55281, Indonesia, Tel +62 274 560700, Email yohanes.widodo@ugm.ac.idBackground: Autologous non-cultured cell (ANCC) spray has been used to treat burns, chronic wounds, and vitiligo, but its use in junctional epidermolysis bullosa (JEB) has not been published previously. …”
Get full text