Insulin Resistance Associated with Plasma Xanthine Oxidoreductase Activity Independent of Visceral Adiposity and Adiponectin Level: MedCity21 Health Examination Registry by Masafumi Kurajoh, Shinya Fukumoto, Takayo Murase, Takashi Nakamura, Takuma Ishihara, Hirofumi Go, Kouji Yamamoto, Shinya Nakatani, Akihiro Tsuda, Tomoaki Morioka, Katsuhito Mori, Yasuo Imanishi, Masaaki Inaba, Masanori Emoto

“…Higher levels of uric acid production have been reported in individuals with visceral fat obesity, and obesity is known to enhance xanthine oxidoreductase (XOR) activity, although the precise mechanism remains unclear. …”
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Exploring the Chemical Constituents, Antioxidant, Xanthine Oxidase and COX Inhibitory Activity of <i>Commiphora gileadensis</i> Commonly Grown Wild in Saudi Arabia by Khalid A. Shadid, Ashok K. Shakya, Rajashri R. Naik, Talal S. Al-Qaisi, Ghaleb A. Oriquat, Ali M. Atoom, Husni S. Farah

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Molecular Structure, Antioxidant Potential, and Pharmacokinetic Properties of Plant Flavonoid Blumeatin and Investigating Its Inhibition Mechanism on Xanthine Oxidase for Hyperuricemia by Molecular Modeling by Cisem Altunayar-Unsalan, Ozan Unsalan

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Simultaneous Determination of Uric Acid and Xanthine Using a Poly(Methylene Blue) and Electrochemically Reduced Graphene Oxide Composite Film Modified Electrode by Gen Liu, Wei Ma, Yan Luo, Deng-ming Sun, Shuang Shao

“…Poly(methylene blue) and electrochemically reduced graphene oxide composite film modified electrode (PMB-ERGO/GCE) was successfully fabricated by electropolymerization and was used for simultaneous determination of uric acid (UA) and xanthine (Xa). Based on the excellent electrocatalytic activity of PMB-ERGO/GCE, the electrochemical behaviors of UA and Xa were studied by cyclic voltammetry (CV) and square wave voltammetry (SWV). …”
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α-Amyrin and β-Amyrin Isolated from <i>Celastrus hindsii</i> Leaves and Their Antioxidant, Anti-Xanthine Oxidase, and Anti-Tyrosinase Potentials by Tran Duc Viet, Tran Dang Xuan, La Hoang Anh

“…The mixture exhibited a high potential for preventing gout by inhibiting a relevant key enzyme, xanthine oxidase (XO) (IC₅₀ = 258.22 µg/mL). …”
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A Study of the Interaction between Xanthine Oxidase and Its Inhibitors from <i>Chrysanthemum morifolium</i> Using Computational Simulation and Multispectroscopic Methods by Sze Ping Wee, Khye Er Loh, Kok Wai Lam, Intan Safinar Ismail

“…The current therapeutic approach for gout is through the inhibition of the xanthine oxidase (XO) enzyme. Allopurinol, a clinically used XO inhibitor, causes many side effects. …”
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Glycoproteomic and Lipidomic Characterization of Industrially Produced Whey Protein Phospholipid Concentrate with Emphasis on Antimicrobial Xanthine Oxidase, Oxylipins and Small Milk Fat Globules by Gulustan Ozturk, Nuanyi Liang, Mrittika Bhattacharya, Randall C. Robinson, Shalini Shankar, Yu-Ping Huang, Bruna Paviani, Ameer Y. Taha, Daniela Barile

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Effects of early aminophylline therapy on clinical outcomes in premature infants by Yi-Ting Chu, Jin-Shuen Chen, Yao-Shen Chen, Chih-Chieh Yang, Chun-Hao Yin, Hsiao-Ping Wang, Yee-Hsuan Chiou

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Preventive Effects of Fucoidan and Fucoxanthin on Hyperuricemic Rats Induced by Potassium Oxonate by Yung-Tsung Chau, Hsin-Yuan Chen, Po-Han Lin, Shih-Min Hsia

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Application of Liquid Chromatography Coupled to Mass Spectrometry for Direct Estimation of the Total Levels of Adenosine and Its Catabolites in Human Blood by Jakub Šofranko, Peter Mitro, Zora Lazúrová, Martin Jozef Péč, Tomáš Bolek, Renata Péčová, Matúš Dohál, Matej Samoš, Radovan Murín

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Urate-lowering therapy for heart failure by O. V. Zhelyabina, M. S. Eliseev

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Formulation Development of Fast Dissolving Microneedles Loaded with Cubosomes of Febuxostat: In Vitro and In Vivo Evaluation by Brijesh Patel, Hetal Thakkar

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Targeting Liver <i>Xor</i> by GalNAc-siRNA Is an Effective Strategy for Hyperuricemia Therapy by Huiyan Sun, Xinxia Wang, Yongqiang Li, Yingzhi Shen, Lin Zhang, Yingjie Xu, Junling Liu, Xuemei Fan

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Effects and Mechanism of Akkermansia muciniphila on Serum Uric Acid and Tissue Inflammation in Hyperuricemic Mice by ZHANG Lihua, LIU Jiaxiu, XIA Xiaodong

Subjects: “…akkermansia?muciniphila; xanthine oxidase; inflammatory response…”
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Theobromine for treatment of uric acid stones and other diseases by Alberto Trinchieri

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Molybdenum Cofactor Biology and Disorders Related to Its Deficiency; A Review Study by Navid Ghasemzadeh, Elham Karimi-Nazari, Fatemeh Yaghoubi, Sadegh Zarei, Fatemeh Azadmanesh, Javad Zavar Reza, Saman Sargazi

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Delayed hypersensitivity reaction to allopurinol: A case report by Mohammad Che Man, Shahidah Che Alhadi, Wan Fatimah Suriyani Wan Mahmud, Salman Amiruddin, Mohd Zhafri Mohd Razib, Rasimah Ismail

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Available treatment options for hyperuricemic patients by Mihai-Emil Gherghina, Ileana Peride, Mirela Tiglis, Tiberiu Paul Neagu, Andrei Niculae, Ionel Alexandru Checherita

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Quantitative Structure–Neurotoxicity Assessment and In Vitro Evaluation of Neuroprotective and MAO-B Inhibitory Activities of Series <i>N</i>′-substituted 3-(1,3,7-trimethyl-xanthin-8-ylthio)propanehydrazides by Magdalena Kondeva-Burdina, Javor Mitkov, Iva Valkova, Lily Peikova, Maya Georgieva, Alexander Zlatkov

Subjects: “…xanthine…”
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Hydroxysafflor Yellow A Inhibits LPS-Induced NLRP3 Inflammasome Activation via Binding to Xanthine Oxidase in Mouse RAW264.7 Macrophages by Xiaolong Xu, Yuhong Guo, Jingxia Zhao, Ning Wang, Junying Ding, Qingquan Liu

“…In this study, we predicted the potential interaction between HSYA and xanthine oxidase (XO) via PharmMapper inverse docking and confirmed the binding inhibition via inhibitory test (IC50 = 40.04 μM). …”
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