Structure–Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase by Ling-Yun Zhou, Jia-Le Peng, Jun-Ming Wang, Yuan-Yuan Geng, Zhi-Li Zuo, Yan Hua

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Recent Advances in the Synthesis of Xanthines: A Short Review by Anandi Kapri, Nitin Gupta, Sumitra Nain

“…Xanthine and its derivatives are considered a pharmacologically potential moiety that manifests immense biological activities. …”
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Side Effects and Interactions of the Xanthine Oxidase Inhibitor Febuxostat by Andreas Jordan, Ursula Gresser

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Raman and Computational Study on the Adsorption of Xanthine on Silver Nanocolloids by Francesco Muniz-Miranda, Alfonso Pedone, Maurizio Muniz-Miranda

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Implication of changes in xanthine oxidase activity following hemodialysis by Hayato Fujioka, Tsutomu Koike, Teruhiko Imamura, Kota Kakeshita, Hidenori Yamazaki, Koichiro Kinugawa

Subjects: “…Xanthine oxidase…”
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Inhibitory activity of xanthine oxidase by fractions Crateva adansonii by A Abdullahi, RU Hamzah, AA Jigam, A Yahya, AY Kabiru, H Muhammad, S Sakpe, FS Adefolalu, MC Isah, MZ Kolo

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Advances in structures required of polyphenols for xanthine oxidase inhibition by Liangliang Liu, Li Zhang, Licheng Ren, Yixi Xie

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Inhibition Effect and Molecular Mechanism of Hypericin on Xanthine Oxidase by Min WANG, Guohui XU, Yiling ZHAO, Gangqiang WANG, Ganhui HUANG

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DESIGN AND PREPARATION SET OF COMPOUNDS AS INHIBITOR OF XANTHINE OXIDASE by BILAL MOHAMMED, SURA UBAID

“…The aim of this study is to design and prepare set of compounds can work as patent inhibitors of xanthine oxidase .The designing of inhibitors was carried out via MOE software and then after choosing the best theoretical inhibitor we prepared, dentified and characterize them by FT-IR, 1HNMR and13CNMR spectroscopy, and C.H.N elements data and the effectiveness of the prepared compounds to inhibit the enzyme XO in vitro.…”
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Metabolic syndrome and cancer risk: The role of xanthine oxidoreductase by Maria Giulia Battelli, Massimo Bortolotti, Letizia Polito, Andrea Bolognesi

“…Keywords: Cancer risk, Inflammation, Metabolic syndrome, Oncogenesis, Oxidative stress, Xanthine oxidoreductase…”
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Antioxidant and xanthine oxidase inhibitory activities of persicaria hydropiper. by Noor Hashim, Noor Haslinda, Abas, Faridah, Shaari, Khozirah, Lajis, Md Nordin

“…Meanwhile, both fractions also were shown to inhibit xanthine oxidase activity compared to other fractions with IC50 values of 28.72 and 165.25 μg/ml. …”
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Development of a New Reporter Gene System-dsRed/Xanthine Phosphoribosyltransferase-Xanthine for Molecular Imaging of Processes Behind the Intact Blood-Brain Barrier by Mikhail Doubrovin, Vladimir Ponomarev, Inna Serganova, Suren Soghomonian, Tadashi Myagawa, Tatiana Beresten, Lyudmila Ageyeva, Michel Sadelain, Jason Koutcher, Ronald G Blasberg, Juri G. Gelovani Tjuvajev

“…We report the development of a novel dual-modality fusion reporter gene system consisting of Escherichia coli xanthine phosphoribosyltransferase (XPRT) for nuclear imaging with radiolabeled xanthine and Discosoma red fluorescent protein for optical fluorescent imaging applications. …”
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Xanthine oxidase inhibitors are associated with reduced risk of cardiovascular disease by Hirotaka Saito, Kenichi Tanaka, Tsuyoshi Iwasaki, Akira Oda, Shuhei Watanabe, Makoto Kanno, Hiroshi Kimura, Michio Shimabukuro, Koichi Asahi, Tsuyoshi Watanabe, Junichiro James Kazama

“…However, we have not been able to determine whether the use of xanthine oxidase inhibitors can reduce cardiovascular disease. …”
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Screening medicinal plant extracts for xanthine oxidase inhibitory activity by A. C. Ha, Ch. D.P. Nguyen, T. M. Le

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Research advances in the therapeutic potential of xanthine oxidoreductase inhibitors for periodontitis by LI Yongshan, WU Zhicong, WANG Zixing, YU Xihuang, LIU Xi, YU Ting

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Indirect Antioxidant Effects of the Nitrite Anion: Focus on Xanthine Oxidase by Xena M. Williams, Alec T. Bossert, Evan Devalance, Sara E. Lewis, Michael R. Gunther, Eric E. Kelley

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Malaria inflammation by xanthine oxidase‐produced reactive oxygen species by Maureen C Ty, Marisol Zuniga, Anton Götz, Sriti Kayal, Praveen K Sahu, Akshaya Mohanty, Sanjib Mohanty, Samuel C Wassmer, Ana Rodriguez

“…We observed that extracellular reactive oxygen species (ROS) produced by xanthine oxidase (XO), an enzyme upregulated during malaria, induce a strong inflammatory cytokine response in primary human monocyte‐derived macrophages. …”
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The Antioxidant and Xanthine Oxidase Inhibitory Activity of Plumeria rubra Flowers by Siti Sarwani Putri Mohamed Isa, Abdulwali Ablat, Jamaludin Mohamad

Subjects: “…xanthine oxidase…”
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Syntheses, Crystal Structures and Xanthine Oxidase Inhibitory Activity of Aroylhydrazones by Yong-Jun Han, Xue-Yao Guo, Ling-Wei Xue

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Oxidized Resveratrol Metabolites as Potent Antioxidants and Xanthine Oxidase Inhibitors by Orinamhe G. Agbadua, Norbert Kúsz, Róbert Berkecz, Tamás Gáti, Gábor Tóth, Attila Hunyadi

“…Chemical oxidation of resveratrol and a bioactivity-guided isolation strategy using xanthine oxidase (XO) and radical scavenging activities led to the isolation of a diverse group of compounds, including a chlorine-substituted compound (<b>2</b>), two iodine-substituted compounds (<b>3</b> and <b>4</b>), two viniferins (<b>5</b> and <b>6</b>), an ethoxy-substituted compound (<b>7</b>), and two ethoxy-substitute,0d dimers (<b>8</b> and <b>9</b>). …”
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