SERS, XPS and DFT Study of Xanthine Adsorbed on Citrate-Stabilized Gold Nanoparticles by Stefano Caporali, Francesco Muniz-Miranda, Alfonso Pedone, Maurizio Muniz-Miranda

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Tissue xanthine oxidoreductase activity in a mouse model of aristolochic acid nephropathy by Takeo Ishii, Tomohiro Kumagae, Hiromichi Wakui, Shingo Urate, Shohei Tanaka, Eriko Abe, Toru Suzuki, Takahiro Yamaji, Sho Kinguchi, Ryu Kobayashi, Kotaro Haruhara, Takashi Nakamura, Shuzo Kobayashi, Kouichi Tamura

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Anti-Hyperuricemic and Xanthine Oxidase Inhibitory Effects of Pogostemon cablin (Blanco) Benth. by Bui Thanh Tung*, Do Thi Hong Khanh, Nguyen Thi Thuy, Trinh Mai Phuong, Nguyen Thi Minh Anh

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Antioxidant Activity of Some Plant Extracts Towards Xanthine Oxidase, Lipoxygenase and Tyrosinase by Pi-Yu Chen, Tzong-Huei Lee, Hsin-Yi Ho, Yi-Tsu Chu, Hsiu-Chen Chan, Chin-Hui Chen, Ching-Kuo Lee

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Mechanisms underlying the xanthine oxidase inhibitory effects of dietary flavonoids galangin and pinobanksin by Yi Dong, Huihua Huang, Mouming Zhao, Dongxiao Sun-Waterhouse, Lianzhu Lin, Chuqiao Xiao

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Xanthine dehydrogenase as a prognostic biomarker related to tumor immunology in hepatocellular carcinoma by Zhen Lin, Yi-Zhao Xie, Ming-Chun Zhao, Pin-Pin Hou, Juan Tang, Guang-Liang Chen

“…Abstract Background Xanthine dehydrogenase (XDH) is a critical enzyme involved in the oxidative metabolism of purines, pterin and aldehydes and a central component of the innate immune system. …”
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Critical role for uricase and xanthine dehydrogenase in soybean nitrogen fixation and nodule development by Cuong X. Nguyen, Alice Dohnalkova, C. Nathan Hancock, Kendall R. Kirk, Gary Stacey, Minviluz G. Stacey

“…Using a forward genetic approach, as well as CRISPR/Cas9 gene editing via Agrobacterium rhizogenes‐mediated hairy root transformation, we identified and characterized the role of GmUOX (Uricase) and GmXDH (Xanthine Dehydrogenase) in nitrogen fixation and nodule development in soybean. …”
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Binding Modes of Xanthine‐Derived Selective Allosteric Site Inhibitors of MTHFD2 by Dr. Vibhu Jha, Prof. Dr. Leif A. Eriksson

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The clinical value of serum xanthine oxidase levels in patients with acute ischemic stroke by Hailong Yu, Xin Chen, Xin Guo, Danni Chen, Li Jiang, Yajie Qi, Jun Shao, Luhang Tao, Jing Hang, Guangyu Lu, Yingzhu Chen, Yuping Li

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Kinetic study on the inhibition of xanthine oxidase by acylated derivatives of flavonoids synthesised enzymatically by Maria Elisa Melo Branco de Araújo, Yollanda Edwirges Moreira Franco, Thiago Grando Alberto, Marcia Cristina Fernandes Messias, Camila Wielewski Leme, Alexandra Christine Helena Frankland Sawaya, Patricia de Oliveira Carvalho

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Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk. by Ryan E Feaver, M Scott Bowers, Banumathi K Cole, Steve Hoang, Mark J Lawson, Justin Taylor, Brian D LaMoreaux, Lin Zhao, Brad R Henke, Brian A Johns, Andrew C Nyborg, Brian R Wamhoff, Robert A Figler

“…These results were replicated with a febuxostat analog, but not another structurally distinct xanthine oxidase inhibitor that does not confer cardiovascular risk. …”
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Xanthine oxidase-lactoperoxidase system and innate immunity: Biochemical actions and physiological roles by Saad S. Al-Shehri, John A. Duley, Nidhi Bansal

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Efficient and Practical Radiosynthesis of Novel [131I]-Xanthine and [131I]-Hypoxanthine by H. Wongso, W. Nuraeni, E. Rosyidiah

Subjects: “…xanthine…”
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Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases by Michał Załuski, Tadeusz Karcz, Anna Drabczyńska, Christin Vielmuth, Agnieszka Olejarz-Maciej, Monika Głuch-Lutwin, Barbara Mordyl, Agata Siwek, Grzegorz Satała, Christa E. Müller, Katarzyna Kieć-Kononowicz

“…Multitarget drugs based on a hybrid dopamine–xanthine core were designed as potential drug candidates for the treatment of neurodegenerative diseases. …”
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Discovery of Novel Allopurinol Derivatives with Anticancer Activity and Attenuated Xanthine Oxidase Inhibition by Yong Li, Ting-Ting Cao, Shanchun Guo, Qiu Zhong, Cai-Hu Li, Ying Li, Lin Dong, Shilong Zheng, Guangdi Wang, Shu-Fan Yin

“…A series of pyrazolo[3,4-d]pyrimidine derivatives related to allopurinol has been synthesized and evaluated for its cytotoxicity against a panel of three cancer cell lines as well as its xanthine oxidase (XOD) inhibitory activities. Among them, compound 4 showed potent cytotoxicity with IC50 values of 25.5 and 35.2 μM against human hepatoma carcinoma cell lines, BEL-7402 and SMMC-7221, respectively. …”
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Association of serum xanthine oxidase levels with hypertension: a study on Bangladeshi adults by Rakib Miah, Khandaker Atkia Fariha, Sabrina Amita Sony, Shamim Ahmed, Mahmudul Hasan, Ananya Dutta Mou, Zitu Barman, Akibul Hasan, Nayan Chandra Mohanto, Nurshad Ali

“…Abstract Xanthine oxidase (XO) is a metalloflavoenzyme associated with the uric acid formation in purine metabolism. …”
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Stilbene compounds are specific inhibitors of the superoxide anion generation catalyzed by xanthine oxidase by Noriyoshi Masuoka

“…The inhibitory effect of xanthine oxidase (XO) reactions with stilbene compounds, 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging by stilbene compounds and superoxide anion (O2-) scavenging activity were examined. …”
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Effect of Xanthine Oxidase Inhibition on Arterial Stiffness in Patients With Chronic Heart Failure by Manal M Alem, Abdullah M Alshehri, Peter MB Cahusac, Matthew R Walters

“…Background: The xanthine oxidase inhibitor allopurinol improves endothelial function in different populations, including patients with chronic heart failure (CHF). …”
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Comprehensive analysis of the relationship between xanthine oxidoreductase activity and chronic kidney disease by Yiyuan Zhang, Xiaobao Ding, Lihao Guo, Yanan Zhong, Juan Xie, Yong Xu, Hailun Li, Donghui Zheng

“…However, the potential relationship between xanthine oxidoreductase (XOR) activity and CKD remains unclear. …”
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Is Xanthine Oxidase, a Marker in Pre-eclampsia? A Case-Control Study by Vanishree Bambrana, C.D.Dayanand, Pushpa P Kotur

“…The objective of the study was to evaluate the plasma levels of Xanthine oxidase (XO) activity, uric acid and Nitric oxide (NO) levels in women with pre-eclampsia and normal pregnancy during antenatal and postpartum period. …”
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