Electrospun nanofibers of collagen and chitosan for tissue engineering and drug delivery applications: A review by Ramakrishnan, Praveen, Ramprasath, Ramakrishnan, Jalaludeen, Abdulkadhar Mohamed, R., Jayakumar, Gimbun, Jolius, Balu, Ranganathan, S.B., Mohamed, T.M., Sridhar, Gunasekaran, Sivagaami Sundari, Davoodbasha, MubarakAli, Thajuddin, Nooruddin, Gnanasekaran, Lalitha, Sundaram, Thanigaivel

“…Studies concerning the medical applications of these nanofibers, such as wound healing, skin regeneration, bone tissue engineering, and neural repair, were also reviewed. …”
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Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol by Svensson, Jonas E., Bolin, Martin, Thor, Daniel, Williams, Pete A., Brautaset, Rune, Carlsson, Marcus, Sörensson, Peder, Marlevi, David, Spin-Neto, Rubens, Probst, Monika, Hagman, Göran, Morén, Anton Forsberg, Kivipelto, Miia, Plavén-Sigray, Pontus

“…As exploratory outcomes, the study will assess change in multiple age-related pathological processes, such as periodontal inflammation, retinal degeneration, bone mineral density loss, atherosclerosis and decreased cardiac function. …”
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Emerging roles of downstream of kinase 3 in cell signaling by Loh, Jia Tong, Teo, Joey Kay Hui, Lim, Hong-Hwa, Lam, Kong-Peng

“…In this review, we will focus on the structure and expression profile of Dok-3 and highlight its role during signal transduction in B cells, innate cells as well as in bone and lung tissues.…”
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Mechano-responsive hydrogel for direct stem cell manufacturing to therapy by Shou, Yufeng, Liu, Ling, Liu, Qimin, Le, Zhicheng, Lee, Khang Leng, Li, Hua, Li, Xianlei, Koh, Dion Zhanyun, Wang, Yuwen, Liu, Tong Ming, Yang, Zheng, Lim, Chwee Teck, Cheung, Christine, Tay, Andy

“…Bone marrow-derived mesenchymal stem cell (MSC) is one of the most actively studied cell types due to its regenerative potential and immunomodulatory properties. …”
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Developing a digital phenotype to subdivide adult immunosuppressed COVID-19 outcomes within the English Primary Care Sentinel Network by Leston, M, Kar, D, Forbes, A, Jamie, G, Wimalaratna, R, Jiwani, G, Ordóñez-Mena, JM, Stewart, DE, Whitaker, H, Joy, M, Lee, LYW, Hobbs, FDR, de Lusignan, S

“…Unique categorisations have been introduced, including ‘Bone Marrow Compromised’ and those dedicated to differentiating prescriptions related and unrelated to cancer. …”

Fermented bed flooring systems enhance profitability in smallholder native pig production by Sivilai, Bounlerth, Vongpaserth, Thonglai, Liang, Juan Boo, Bush, Russell

“…There were also no significant differences in growth performance (average daily gain (ADG) and feed conversion ratio (FCR)), and carcass traits, except that pigs from FB had higher hot carcass weight, dressing percentage and rib and bone weights. Native pigs kept in the FB system had significantly higher total production costs because of the cost of the bedding material, but also had four-fold higher net income return generated from the sale of the fermented floor compost. …”

Insights on the characteristics and therapeutic potential of mesenchymal stem cell-derived exosomes for mitigation of Alzheimer’s disease’s pathogenicity: a systematic review by Mohammed Yousuf Abdi, Sarah, Mustaffa Al-Bakri, Siti Sarah, Nordin, Norshariza

“…A total of 17 eligible in vivo and in vitro studies were included in this review. Bone marrow-derived stem cells (BMSCs) were the most used source for exosome isolation, even though studies on exosomes from adipose-derived stem cells (ADSCs) and human umbilical cord stem cells (HUCSCs) provide more information on the characteristics. …”

Le cinéma d’Afrique noire contemporaine: une impossible décolonisation? by Fouhba, H

“…An Africa driven by "primitivity" in the 21st century, and in which witchcraft, early marriages, excision, under-schooling of young people, non-schooling of women, juvenile delinquency, absent civil documentation (marriage and birth certificates) , water-borne diseases and insalubrity… constitute the daily lot of the populations.…”

Boronic acid and nitrofuranyl derivatives as potential therapeutics by Dey, AL

“…‘Rule of 5’, there has been extensive research on lead-like compounds other than those in the realm of small molecule drug-likeness. With this borne in mind Chapter 1, Antimicrobial Peptides – a New Chasm, introduces the concept of protein-protein interactions (PPIs), which could pave the way for development of promising therapeutic agents of various properties such as pacidamycin and muraymycin which are all peptide-based antibiotics that are concerned with PPIs. …”

Metastatic pituitary tumors: an institutional case series by Yearley, Alexander G., Chalif, Eric J., Gupta, Saksham, Chalif, Joshua I., Bernstock, Joshua D., Nawabi, Noah, Arnaout, Omar, Smith, Timothy R., Reardon, David A., Laws, Edward R.

“…Common sites of metastasis included the central nervous system, liver, lung, and bone. In a pooled analysis including additional cases from the literature, treatment of metastases with chemotherapy or a combination of radiation therapy and chemotherapy significantly prolonged PFS (p = 0.02), while failing to significantly improve OS (p = 0.14). …”
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Retention of the structure and function of heparan sulfate biomaterials after gamma irradiation by Smith, Raymond A. A., Chua, R. J. E., Carnachan, Susan M., Tan, Clarissa L. L., Sims, Ian M., Hinkley, Simon F. R., Nurcombe, Victor, Cool, Simon M.

“…Our previous work has demonstrated that a particular affinity-selected HS (referred to henceforth as “HS3”) is capable of enhancing the osteogenic effects of bone morphogenetic protein 2 (BMP2). Here, we gamma-irradiated HS with 26 kGy of ionizing radiation to determine how this affected the structure, composition, and function. …”
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Optimised “green solvent” extraction of long-chain menaquinones (Vitamin K2) from wet Lactococcus lactis biomass by Lee, Sze Ying, Hu, Xiao, Stuckey, David C.

“…Menaquinone (vitamin K2) is an essential fat-soluble vitamin for bone and cardiovascular health. Long-chain menaquinones are exclusively synthesised by bacteria, and Lactococcus lactis appears promising as a microbial production platform. …”
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Direct reuse of electronic plastic scraps from computer monitor and keyboard to direct stem cell growth and differentiation by Shi, Pujiang, Tan, Chiew Kei, Wu, Zhuoran, Gabriel, Jean-Christophe P., Srinivasan, Madhavi, Lee, Jong-Min, Tay, Chor Yong

“…Interestingly, compared to commercial tissue-culture treated plastics and in a competitive adipogenic and osteogenic differentiation environment, ADSCs cultured on the keyboard and light diffuser plastics favoured bone cells formation while the grating-like microstructures of the prismatic sheet promoted fat cells differentiation via the process of contact guidance. …”
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Biocompatible materials for orbital wall reconstruction - an overview by Vasile, Victor A., Istrate, Sinziana, Iancu, Raluca C., Piticescu, Roxana M., Cursaru, Laura M., Schmetterer, Leopold, Garhöfer, Gerhard, Cherecheanu, Alina Popa

“…The reconstruction materials can be divided into autografts (bone or cartilage tissue) or allografts (metals, ceramics, or plastic materials, and combinations of these materials). …”
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Reassessing the association: evaluation of a polyalanine deletion variant of RUNX2 in non-syndromic sagittal and metopic craniosynostosis by Walton, IS, McCann, E, Weber, A, Morton, JEV, Noons, P, Wilson, LC, Ching, RC, Cilliers, D, Johnson, D, Phipps, JM, Shears, DJ, Thomas, GPL, Wall, SA, Twigg, SRF, Wilkie, AOM

“…(Ala84_Ala89)del, occurs in humans (termed 11A allele), and a previous association study (Cuellar et al. Bone 137:115395;2020) reported that the 11A variant was significantly more frequent in non-syndromic sagittal craniosynostosis (nsSag; allele frequency [AF] = 0.156; 95% confidence interval [CI] 0.126–0.189) compared to non-syndromic metopic craniosynostosis (nsMet; AF = 0.068; 95% CI 0.045–0.098). …”

Soft tissue tumor imaging in adults: whole-body staging in sarcoma, non-malignant entities requiring special algorithms, pitfalls and special imaging aspects. Guidelines 2024 from... by Noebauer-Huhmann, I, Vanhoenacker, FM, Vilanova, JC, Tagliafico, AS, Weber, M, Lalam, RK, Grieser, T, Nikodinovska, VV, de Rooy, JWJ, Papakonstantinou, O, Mccarthy, C, Sconfienza, LM, Verstraete, K, Martel-Villagrán, J, Szomolanyi, P, Lecouvet, FE, Afonso, D, Albtoush, OM, Aringhieri, G, Arkun, R, Aström, G, Bazzocchi, A, Botchu, R, Breitenseher, M, Chaudhary, S, Mansour, RM

“…Whole-body MRI is preferred for staging bone metastasis, with [18F]FDG-PET/CT as an alternative modality in PET-avid tumors. …”

Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Shamsi, ZA, Paraoan, V, Kim, C, Saifuddin, SR, Cosker, TDA, Whitwell, D, Gibbons, CLMH, Stavroulias, D, DiChiara, F

“…This approach necessitates a multidisciplinary team, ideally in specialised cancer centres. The Oxford Bone and Soft Tissue Tumour Service is one such centre, and routinely treats such cancers through collaboration between orthopaedic oncology and cardiothoracic surgeons, as well as members of the wider MDT. …”

Association between feel-like temperatures and injury risk during international outdoor athletic championships: a prospective cohort study on 29 579 athlete starts during 10 champi... by Edouard, P, Dandrieux, P-E, Klöwer, MK, Junge, A, Racinais, S, Branco, P, Hollander, K, Navarro, L

“…We performed Poisson regressions with incidence rates (number of injuries per 1000 athlete starts) as outcomes and UTCI as a predictive variable adjusted for sex, for all and time-loss injuries, for different injured tissue types (ie, muscle, tendon, ligament, articular, bone and skin) and specific discipline (ie, sprints, hurdles, jumps, throws, middle distance, long distance, marathon and race walking).…”

Electromyography signal processing based on time and time-frequency representations for prosthesis application by Mahdavi, Farzaneh Akhavan

“…Skeletal muscles are attached to the bone responsible for the movements of the human body. …”
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Using cluster analysis to reconstruct dengue exposure patterns from cross-sectional serological studies in Singapore by Sangkaew, Sorawat, Tan, Li Kiang, Ng, Lee Ching, Ferguson, Neil M., Dorigatti, Ilaria

“…Background: Dengue is a mosquito-borne viral disease caused by one of four serotypes (DENV1-4). …”
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