The impact of natural climate variability on the global distribution of Aedes aegypti: a mathematical modelling study by Kaye, AR, Obolski, U, Sun, L, Hart, WS, Hurrell, JW, Tildesley, MJ, Thompson, RN

“…Some regions could experience vector-borne disease outbreaks earlier than expected under climate change alone. …”

In vitro bioactivity and biocompatibility assessment of PCL/PLA–scaffolded mesoporous silicate bioactive glass: role of boron activation by Md. Zain, Siti Khalijah, Sazali, Ezza Syuhada, Ghoshal, Sib Krishna, Hisam, Rosdiyana

“…Bioactive glasses with rapid biodegradation and efficient biomineralization for damaged bone tissue repair remain deficient. Based on this fact, some new types of boron-activated mesoporous Bioactive silicate glasses (BMSGs) were made to determine the feasibility of achieving their improved mechanical strength, structure, porosity, biodegradability and bone healing performance. …”

Experimental investigation into load settlement characteristics of piled rafts in sand by Leong, Hazel Xueling.

“…Studies by many notable researchers in the years to come suggest that the most effective combinations of piles and raft happens when all the initial loading can be borne with the raft’s bearing capacity alone. The role of the piles was solely to reduce the excessive settlement experienced by the plain raft.…”
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The rickettsial effector Sca4 has a conserved interaction with host clathrin and a tick cell specific role in infection by Vondrak, Cassandra Joan

“…Rickettsia species are obligate intracellular bacteria that cause vector-borne diseases that constitute an ongoing public health threat. …”
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The post-modern Japanese identity of Haruki Murakami's literature. by Ling, Shannon.

“…The year was 1889 when William Butler Yeats, arguably one of the foremost important figures in 20th century literature, declared that “there is no fine nationality without literature, and… no fine literature without nationality” (Allison 238). …”
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The 'Clisurean' finds from Climente II cave, Iron Gates, Romania by Bonsall, C, Boroneanţ, A, Evatt, A, Soficaru, A, Nica, C, Bartosiewicz, L, Cook, G, Higham, TFG, Pickard, C

“…Single-entity 14C dating of human bone and humanly modified animal bones suggests the Clisurean occupation occurred during the Bølling–Allerød warm period. …”

Causal inference in health and disease: a review of the principles and applications of Mendelian randomization by Lovegrove, CE, Howles, SA, Furniss, D, Holmes, MV

“…This review provides a framework to enhance understanding of how MR may be used to triangulate evidence and progress research in bone and mineral metabolism as we strive to infer causal effects in health and disease.…”

Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotype by de Vos, Ivo J. H. M., Goggi, Julian L., Wilson, Gabrielle R., Stegmann, Alexander P. A., Amor, David J., Dunn, Norris Ray, Carney, Thomas James, Lockhart, Paul J., Coull, Barry J., van Steensel, Maurice A. M., Tao, Evelyn Yaqiong, Ong, Sheena Li Ming, Scerri, Thomas, Low, Chernis Guai Mun, Wong, Arnette Shi Wei, Grussu, Dominic, van Geel, Michel, Janssen, Renske, Bahlo, Melanie

“…Notably, the zebrafish model will be a valuable tool for developing novel therapeutic approaches to a devastating bone disorder.…”
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Morphological multiparameter filtration and persistent homology in mitochondrial image analysis by Chung, Yu-Min, Hu, Chuan-Shen, Sun, Emily, Tseng, Henry C.

“…Mutations in the autophagy gene Optineurin (OPTN) are associated with primary open-angle glaucoma (POAG), amyotrophic lateral sclerosis (ALS), and Paget's disease of the bone, but the pathophysiological mechanism is unclear. …”
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Comparison of a simplified skin pointer device compared with a skeletal marker for knee rotation laxity : a cadaveric study using a rotation-meter by Puah, Ken Lee, Yew, Andy Khye Soon, Chou, Siaw Meng, Lie, Denny Tijauw Tjoen

“…METHODS : Six pairs of cadaveric legs were mounted on a knee rotation jig. One Kirscher wire was driven into the tibial tubercle as a bone marker and a skin pointer was attached. …”
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Clinical, genetic and omics-based biomarkers that might support the identification of the development of psoriatic arthritis in individuals with psoriasis – a narrative review of t... by Grohmann, T, Vivekanantham, A, Coates, L, Pennington, S, FitzGerald, O

“…Furthermore, there are considerable delays in diagnosis and treatment of PsA, which lead to joint and bone deformation and chronic pain. It is therefore important to develop more precise diagnostic and screening tools. …”

BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress by Vasudevarao, MD, Posadas Pena, D, Ihle, M, Bongiovanni, C, Maity, P, Geissler, D, Mohammadi, HF, Rall-Scharpf, M, Niemann, J, Mommersteeg, MTM, Redaelli, S, Happ, K, Wu, C, Beisaw, A, Scharffetter-Kochanek, K, D’Uva, G, Malek Mohammadi, M, Wiesmüller, L, Geiger, H, Weidinger, G

“…Surprisingly, we found that regenerating cardiomyocytes experience DNA replication stress, which represents one reason for declining tissue regeneration during aging in mammals. …”

Exploring the dynamics of gene drive mosquitoes within wild populations using an agent-based simulation by Wickramasooriya, S, Mahmood, I, Calinescu, A, Wooldridge, M, Lanzaro, G

“…Gene drive technology is emerging as a potentially powerful tool in combating vector-borne diseases – notably malaria. This study introduces an agent-based model (ABM) focused on the deployment of genetically engineered mosquitoes with gene drive (GEM) in Príncipe Island, Republic of São Tomé and Príncipe, an island nation in the Gulf of Guinea, West Africa. …”

Effectiveness of supervised versus self-directed rehabilitation for adults aged 50 years and over with ankle fractures: protocol for the AFTER trial by Keene, DJ, Achten, J, Forde, C, Png, ME, Grant, R, Draper, K, Appelbe, D, Tutton, E, Peckham, N, Dutton, SJ, Lamb, SE, Costa, ML

“…Participants will be randomized 1:1 using a web-based service to supervised rehabilitation (four to six one-to-one physiotherapy sessions of tailored advice and prescribed home exercise over three months), or self-directed rehabilitation (provision of advice and exercise materials that participants will use to manage their recovery independently). …”

A generic micropatterning platform to direct human mesenchymal stem cells from different origins towards myogenic differentiation by Tan, Lay Poh, Yu, Ting, Chua, Chee Kai, Tay, Chor Yong, Wen, Feng, Yu, Haiyang, Chan, Jerry Kok Yen, Chong, Mark Seow Khoon, Leong, David Tai Wei

“…Recent work shows that cell shape manipulation via micropatterning can modulate the differentiation of bone-marrow-derived MSCs. Herein, the effect of micropatterning on the myogenesis of MSCs isolated from three different sources (bone marrow, fetal tissue, and adipose) is reported. …”
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Specific inhibition of PI3K p110δ inhibits CSF‐1‐induced macrophage spreading and invasive capacity by Mouchemore, KA, Sampaio, N, Murrey, MW, Stanley, ER, Lannutti, BJ, Pixley, FJ

“…Here we show that pY721‐based signaling is necessary for CSF‐1‐stimulated PtdIns(3,4,5)P production. While primary bone marrow‐derived macrophages and the immortalized bone marrow‐derived macrophage cell line M−/−.WT express all three class IA PI3K isoforms, p110δ predominates in the cell line. …”

Infectious diseases acquired by international travellers visiting the USA by Stoney, Rhett J, Esposito, Douglas H., Kozarsky, Phyllis, Hamer, Davidson H., Grobusch, Martin P., Gkrania-Klotsas, Effrossyni, Libman, Michael, Gautret, Philippe, Lim, Poh Lian, Leder, Karin, Schwartz, Eli, Sotir, Mark J., Licitra, Carmelo

“…Lyme disease was the most frequently reported arthropod-borne disease after travel (42, 4%). Nonspecific respiratory, gastrointestinal and systemic infections were also among the most frequently reported diagnoses overall. …”
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Synthesis and application of titanium dioxide nanotube and composites by Liang, Kun

“…Titanium dioxide (TiO2) nanotube has been demonstrated to be one of popular material in many research areas. …”
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The medium-term results of arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of femoroacetabular impingement syndrome: a multicentre... by Palmer, A, Fernquest, S, Logishetty, K, Rombach, I, Harin, A, Mansour, R, Dijkstra, P, Andrade, T, Dutton, S, Glyn-Jones, S

Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta by Kausar, Mehran, Saima Siddiqi, Muhammad Yaqoob, Sajid Mansoor, Makitie, Outi, Asif Mir, Khor, Chiea Chuen, Foo, Jia Nee, Anees, Mariam

“…Results:Nine affected family members exhibited severe bone deformities, recurrent fractures, short stature and low bone mineral density. …”
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