Computational Approaches for Understanding and Redesigning Enzyme Catalysis by Karvelis, Elijah

“…These variations in mutant activity on AHB were explained by analysis of WT-AHB simulations, which showed that only some of the structural mechanisms related to enhanced ACL catalysis transferred to, and thereby facilitated, AHB catalysis. This thesis highlights the influence of conformational states that are visited during the dynamics of substrate turnover and their role on enzyme catalysis, and it furthermore suggests a framework with which researchers may consider and apply these effects when engineering catalytic function.…”
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The peculiarities of knowledge management processes in SMEs : the case of Singapore by Wee, Janet Chui Neo, Chua, Alton Yeow Kuan

“…In SMEs, knowledge creation takes the form of innovative customized solutions to meet customers' needs; knowledge sharing occurs through cross functionality, overlapping roles, and facilitated by close physical proximity in open workspaces; and knowledge reuse is often made tacitly, where common knowledge is prevalently embedded within the KM processes of SMEs. …”
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Cold atoms laboratory in a hollow core fiber by Leong, Wui Seng

“…Moreover, I create a 1D array of Schr\"odinger cats states in facilitated by an optical lattice in the HCF and study its potential for applications in quantum sensing and quantum simulation in HCF. …”
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Host genotype and microbiome associations in co-occurring clonal and non-clonal kelp, Ecklonia radiata by Gonzalez, Sebastian Vadillo, Vranken, Sofie, Coleman, Melinda A., Wernberg, Thomas, Steinberg, Peter D., Marzinelli, Ezequiel Miguel

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Waste palm leaves-based hydrochar support catalytic esterification of palm fatty acid distillate by Aliyu, Muhammad, Rashid, Umer, Wan Ab Karim Ghani, Wan Azlina, Mohd Salleh, Mohamad Amran, Hazmi, Balkis, Alharthi, Fahad A., Antunes, Elsa, Yu, Jianglong

“…The significant acidity density (18.57 mmol/g) facilitated the simultaneous esterification process. …”

Simplified hybrid control strategy for stand-alone DC microgrid with photovoltaic system to extend battery lifespan by Yan, Hein Wai, Farivar, Glen G., Tafti, Hossein Dehghani, Ceballos, Salvador, Pou, Josep

“…Additionally, the proposed solution does not require the knowledge of the load, which facilitates its application. The effectiveness of the proposed control strategy is validated with simulation results.…”
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Hospitalised patients as stewards of their own antibiotic therapy: a qualitative analysis informing the strategic design of interventions to encourage shared decision-making in ter... by Guo, Huiling, Lye, David C., Ng, Tat Ming, Somani, Jyoti, Kwa, Andrea Lay Hoon, Chung, Jasmine Shimin, Chow, Angela

“…Understanding the facilitators and barriers to SDM can inform the design and implementation of interventions to empower these patients to engage in SDM on their antibiotic therapies. …”
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All carbon based high energy lithium-ion capacitors from biomass : the role of crystallinity by Sennu, Palanichamy, Arun, Nagasubramanian, Madhavi, Srinivasan, Aravindan, Vanchiappan, Lee, Yun-Sung

“…This results clearly demonstrate that the surface functionality and heteroatom doping with tubular structure synergistically facilitates the Li+ and electron transport properties to realize higher energy density for this fascinating all carbon-based Li-ion capacitor.…”
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Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1 by Zhang, Kuo, Law, Yee-Song, Law, Michelle Cheok Yien, Tan, Yaw Bia, Wirawan, Melissa, Luo, Dahai

“…The multifunctional CHIKV protein, nsP1, facilitates virus RNA replication and transcription by anchoring the viral replication complex (RC) to plasma membrane vesicles and synthesizing the viral RNA 5' cap-0. …”
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The opioid receptor influences circadian rhythms in human keratinocytes through the β-arrestin pathway by Bigliardi, Paul, Junnarkar, Seetanshu, Markale, Chinmay, Lo, Sydney, Bigliardi, Elena, Kalyuzhny, Alex, Ong, Sheena, Dunn, Ray, Wahli, Walter, Bigliardi-Qi, Mei

“…Furthermore, we observed that β-arrestin-1 regulates the transcription of its target genes, including PER2, by facilitating histone-4 acetylation. Through the ChIP assay, we determined that Met-Enkephalin enhances β-arrestin-1 binding to acetylated H4 in the PER2 promoter. …”
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Identification of bacterial biofilm and the Staphylococcus aureus derived protease, staphopain, on the skin surface of patients with atopic dermatitis by Sonesson, Andreas, Przybyszewska, Kornelia, Eriksson, Sigrid, Mörgelin, Matthias, Kjellström, Sven, Davies, Julia, Potempa, Jan, Schmidtchen, Artur

“…The data presented here provide novel information on staphopains present in S. aureus biofilms in vivo, and illustrate the complex interplay between biofilm and LL-37 in skin of AD patients, possibly leading to a disturbed host defense, which facilitates bacterial persistence.…”
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A molecular dynamics simulation to shed light on the mechanical alloying of an Al-Zr alloy induced by severe plastic deformation by Morkina, Alina Y., Babicheva, Rita I., Korznikova, Elena A., Enikeev, Nariman A., Edalati, Kaveh, Dmitriev, Sergey V.

“…In contrast, the involvement of dislocations in the case of normal orientation of grain boundaries with Zr segregation significantly contributes to deformation and facilitates better dissolution of Zr in the Al matrix. …”
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Function of second cladding layer in hollow core tube lattice fibers by Huang, Xiaosheng, Yoo, Seongwoo, Yong, KenTye

“…A small core, on the other hand, facilitates the gas-filled TLF applications, but at the expense of the increased mode attenuation. …”
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Electrostatic microfiltration (EM) enriches and recovers viable microorganisms at low-abundance in large-volume samples and enhances downstream detection by Liu, Yaoping, Raymond, Joshua J, Wu, Xiaolin, Chua, Patrina Wei Lin, Ling, Sharon Yan Han, Chan, Chia Ching, Chan, Cheryl, Loh, Joanne Xin Yi, Song, Melody Xing Yen, Ong, Matilda Yu Yan, Ho, Peiying, Mcbee, Megan E, Springs, Stacy L, Yu, Hanry, Han, Jongyoon

“…Furthermore, EM-enabled sample preparation facilitates digital amplification techniques sensitively detecting broad pathogens, including bacteria, fungi, and viruses from various samples, in a rapid (≤3 h) sample-to-result workflow. …”
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A weighting factor free model predictive control for a flying capacitor converter in a DC microgrid by Jayan, Vijesh, Amer Mohammad Yusuf Mohammad Ghias

“…The presence of multiple FCs facilitates the converter to interface a low-voltage battery to a high-voltage DC bus at reduced voltage stress on its power switches. …”
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Optical quantum sensing for agnostic environments via deep learning by Zhou, Zeqiao, Du, Yuxuan, Yin, Xu-Fei, Zhao, Shanshan, Tian, Xinmei, Tao, Dacheng

“…This distilled knowledge facilitates the identification of optimal optical setups associated with maximal QFI. …”
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Customer co-creation in B2C e-commerce: does it lead to better new products? by Pee, Loo Geok

“…The business-to-consumer e-commerce platform facilitates direct reach to customers and is especially conducive to large-scale customer co-creation. …”
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Autonomous navigation robot using slam and path planning based on a Single RP-LIDAR by Abu Ubaidah, Shamsudin, Puteri Alisha Balqis, Mohd Sharif, Soomro, Zubair Adil, Ruzairi, Abdul Rahim, Ahmad Athif, Mohd Faudzi, Wan Nurshazwani, Zakaria, Mohamad Heerwan, Peeie, Salaan, Carl John O.

“…First, a global planner, utilizing the A* algorithm, facilitates long-distance trajectory planning while accounting for static obstacles. …”
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Knot optimization for biharmonic B-splines on manifold triangle meshes by Hou, Fei, He, Ying, Qin, Hong, Hao, Aimin

“…The new representation also facilitates optimization-driven knot selection for constructing biharmonic B-splines on manifold triangle meshes. …”
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Selective separation and recovery of lithium, nickel, MnO₂, and Co₂O₃ from LiNi₀.₅Mn₀.₃Co₀.₂O₂ in spent battery by He, Hongping, Feng, Junli, Gao, Xiaofeng, Fei, Xunchang

“…The Co, Ni and Mn ions are dissolved in a sequence, which facilitates their separation and recovery. As the main components of the final residual solids, Co2O3 and MnO2 present in distinctly different sizes and shapes, which are beneficial for their separation and direct usage.…”
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