Association of Indoleamine 2,3-dioxygenase (ido) activity with outcome after cardiac surgery in adult patients by Stieger, A, Huber, M, Yu, Z, Kessler, BM, Fischer, R, Andereggen, L, Kobel, B, Stueber, F, Luedi, MM, Filipovic, MG

“…Increased IDO activity has been observed in various diseases and is associated with worse clinical outcomes. However, comprehensive research regarding its role in cardiac surgery remains limited. …”

Performance and validation of a digital memory test across the Alzheimer’s disease continuum by Toniolo, S, Attaallah, B, Maio, MR, Tabi, YA, Slavkova, E, Klar, VS, Saleh, Y, Idris, MI, Turner, V, Preul, C, Srowig, A, Butler, C, Thompson, S, Manohar, SG, Finke, K, Husain, M

“…A linear support vector model combining digital metrics achieved high accuracy and performed at par with standard testing in discriminating between elderly healthy controls and subjective cognitive decline (area under the curve 0.82) and between subjective cognitive decline and mild cognitive impairment (area under the curve 0.92), while performing worse in classifying between mild cognitive impairment and Alzheimer’s disease patients (area under the curve 0.75). …”

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, RA, Tong, O, Cooper, R, Taylor, CA, Sharma, PK, de Los Aires, AV, Mahé, EA, Ruffieux, H, Nassiri, I, Middleton, MR, Fairfax, BP

“…Last, we demonstrated that individuals whose CD8⁺ T cell pretreatment showed low cytotoxicity and had fewer expanded clones typically had worse outcomes after ICB treatment. This work further advances understanding of the molecular determinants of ICB response, assisting in the search for peripheral prognostic biomarkers and highlighting the importance of the baseline CD8⁺ immune landscape in determining ICB response in metastatic melanoma.…”

Pre-shift anxiety and its factors influencing among nursing students during clinical placement in Universiti Sains Malaysia Health Campus by Ting, Veronica Lim Mei

“…Pre-shift anxiety can cause the healthcare students or healthcare professionals to feel anxious and panic right before starting their work and eventually negatively affect their performance. In a worse-case scenario, this can in turn negatively affect the patient care and patient outcomes. …”
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An Optimal Tradeoff between Entanglement and Copy Complexity for State Tomography by Chen, Sitan, Li, Jerry, Liu, Allen

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High-throughput quantification of quasistatic, dynamic and spall strength of materials across 10 orders of strain rates by Eswarappa Prameela, Suhas, Walker, Christopher C, DiMarco, Christopher S, Mallick, Debjoy D, Sun, Xingsheng, Hernandez, Stephanie, Sasaki, Taisuke, Wilkerson, Justin W, Ramesh, KT, Pharr, George M, Weihs, Timothy P

“…Peak aging, considered to be a standard method to strengthen metallic alloys, causes catastrophic failure, faring much worse than solutionized alloys. Our high-throughput testing framework not only quantifies strength but also teases out unexplored failure mechanisms at extreme strain rates, providing valuable insights for the rapid design and improvement of materials for extreme environments.…”
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Immediate test or delayed test : evidence of primary Mathematics learning by Arunachalam Thannimalai

“…Another preliminary aim is to examine whether conducting a test right after learning would yield worse learning outcomes compared to conducting the test after a break from learning. …”
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Clinical outcomes of patients with unsuccessful mechanical thrombectomy versus best medical management of medium vessel occlusion stroke in the middle cerebral artery territory by Faizy, TD, Yedavalli, V, Salim, HA, Lakhani, DA, Musmar, B, Adeeb, N, Essibayi, MA, Daraghma, M, El Naamani, K, Henninger, N, Sundararajan, SH, Kuhn, AL, Khalife, J, Ghozy, S, Scarcia, L, Yeo, LL, Tan, BY, Regenhardt, RW, Heit, JJ, Cancelliere, NM, Rouchaud, A, Fiehler, J, Sheth, SA, Puri, AS, Dmytriw, AA

“…Conclusion: Unsuccessful MT for MeVO was linked to worse outcomes than best MM. These findings highlight the risks of prolonged attempts and emphasize the importance of efficient procedural decision-making to reduce complications and improve patient outcomes.…”

Quality and outcomes of diabetes care in patients diagnosed with cancer by Griffiths, R

“…Of these 88, 47 (53%; 95% Confidence Interval [CI], 43%-64%) were no different, 12 (14%; 95% CI, 6%-21%) were better, and 29 (33%; 95% CI, 23%-43%) were worse in cancer patients. <b>Results of the Primary Research</b>: The primary research included 3,382 diabetic cancer patients and 11,135 matched, diabetic, non-cancer controls, who were followed from two years before, up to 10 years after, cancer or a matched date in controls. …”

“Encouraged to be your true self”: an interpretative phenomenological study of medical students’ experiences of role models in shaping sexual minority identity at medical school... by Zacharias, A, Aitken, D

“…Sexual and gender minority (SGM) identifying individuals experience worse health outcomes compared to non-SGM identifying counterparts. …”

Evaluating the generalisability of region-naïve machine learning algorithms for the identification of epilepsy in low-resource settings by Duta, I, Kariuki, SM, Ngugi, AK, Mwesige, AK, Masanja, H, Mwanga, DM, Owusu-Agyei, S, Wagner, R, Cross, JH, Sander, JW, Newton, CR, Sen, A, Jones, GD

“…Results: Single-site clinical models performed well within their own regions, but generally worse when evaluated in other regions (p&lt;0.05). …”

Aerodynamic Effects of High-Speed Train Positions During Tunnel Exit Under Crosswind Conditions Using Computational Fluid Dynamics by Rajendran, S, Ishak, I. A, Arafat, M, Mohammad, A. F, Salleh, Z. M, Samiran, N. A, Ja’a, M. N. M, Sulaiman, S

“…The higher crosswind angles including ψ = 45° and ψ = 60° cases produced the worse results of aerodynamic load coefficients compared to the lower crosswind angles of ψ = 15° and ψ = 30°. …”
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The determinants of COVID-19 morbidity and mortality across countries by Chang, Dianna, Chang, Xin, He, Yu, Tan, Kelvin Jui Keng

“…In terms of socio-economic aspects, GDP per capita, income inequality, and happiness (i.e., life satisfaction) lead to worse COVID-19 outcomes. Interestingly, technology advancement increases morbidity but reduces mortality. …”
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Development of a vision-based gesture human-computer interface by Lim, Chun Ping.

“…As images are represented as structures of numbers, extracting accurate information about the hand from the data captured is a daunting task. To make matters worse, attaching meaning to the hand sign and hand motion detected involves high level intelligence which is still elusive to computers. …”
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The outcomes, burdens and experiences of patients receiving immunotherapy for cancer by Wiltshire, R

“…Correlations between outcomes, burdens and experiences, indicating that participants with worse experiences of healthcare, and greater treatment burden also had poorer quality of life.…”

Prognostic significance of pleural fluid microbiological positivity in pleural infection: a bicentric 10-year retrospective observational study by Wong, C, Fan, HC, Rahman, NM, Wong, JCC, Cheng, HS, Chiu, PH, Tong, CW, Miu, FPL, Yam, LYC

“…In the MPPI group, presence of Staphylococcus aureus (aHR 2.26, 95% CI 1.43–3.57) and Gram-negative organisms other than Enterobacteriaceae (aHR 2.00, 95% CI 1.10–3.61) were associated with worse survival, while presence of Streptococcus anginosus group was associated better survival (aHR 0.50, 95% CI 0.32–0.78), when compared to their absence. …”

Acute seizure risk in patients with encephalitis: development and validation of clinical prediction models from two independent prospective multicentre cohorts by Wood, GK, Babar, R, Ellul, MA, Thomas, RH, Van Den Tooren, H, Easton, A, Tharmaratnam, K, Burnside, G, Alam, AM, Castell, H, Boardman, S, Collie, C, Facer, B, Dunai, C, Defres, S, Granerod, J, Brown, DWG, Vincent, A, Marson, AG, Irani, SR, Solomon, T, Michael, BD

“…<p><strong>Objective </strong></p>In patients with encephalitis, the development of acute symptomatic seizures is highly variable, but when present is associated with a worse outcome. We aimed to determine the factors associated with seizures in encephalitis and develop a clinical prediction model. …”

Behaviorally informed digital campaigns and their association with social media engagement and COVID-19 vaccine uptake in Belize by Daga, Giuliana, Kossuth, Lajos, Boruchowicz, Cynthia, Lopez Boo, Florencia, Largaespada Beer, Natalia

“…Conclusions Facebook adverts highlighting vaccine safety had a similar level of social media performance as other campaigns, except for adverts focusing on vaccine efficacy, which performed worse. Communicating side-effect information with words instead of numbers can expand social media interest in low-uptake regions like the Caribbean. …”
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Learning from success, not catastrophe: using counterfactual analysis to highlight successful disaster risk reduction interventions by Rabonza, Maricar, Lin, Yolanda C., Lallemant, David

“…This approach uses counterfactual modelling of a past hazard event with consequences made worse (i.e. downward counterfactual) by the absence of the mitigation intervention. …”
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Study on impacts of engineering strategies on pedestrian behaviour and perceptions at zebra crossings by Ng, Wan Ying

“…To cross the zebra crossings, pedestrians have to depend on themselves to look out for vehicles before and while crossing. To make matters worse, pedestrians nowadays frequently look at their mobile phones while crossing the roads, hence increasing the risk of accidents occurring at the crossings. …”
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