Synthetic approaches to all-porphyrin nanorings by Field, J

“…These tethers could then react together, keeping the oligomer in a cyclic conformation that persists even after removal of the template. …”

Spatial and subcellular gene expression patterns in myogenic differentiation and muscle pathology by Chwalenia, KM

“…Promising dystrophin-restoration therapies such as gene editing using the CRISPR-Cas9 system and antisense oligonucleotide-mediated exon skipping using peptide-phosphorodiamidate morpholino oligomers (PPMOs) are currently in development. The efficacy of these approaches is typically assessed in terms of the amount of dystrophin restored, while correct sarcolemmal localisation of the protein has largely been assumed.…”

Heterogeneous nucleation of polyethylene crystals on binary hexagonal nanoplatelets by Volchko, Nathan W., Rutledge, Gregory C.

“…The strength of interaction between the nucleating agent and the polyethylene oligomer is found to be the strongest predictor of nucleating agent efficiency. …”
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Biophysical properties and supramolecular structure of self-assembled liposome/ε-peptide/DNA nanoparticles : correlation with gene delivery by Yan, Jiang, Korolev, Nikolay, Eom, Khee Dong, Nordenskiöld, Lars, Tam, James P.

“…Using solid-phase synthesis, lysine can be oligomerized by a reaction of the peptide carboxylate with the ε-amino group to produce nontoxic, biodegradable cationic peptides, ε-oligo(l-lysines). …”
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Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors by Shapiguzov, Alexey, Fernie, Alisdair R., Vainonen, Julia P., Hunter, Kerri, Tossavainen, Helena, Tiwari, Arjun, Järvi, Sari, Hellman, Maarit, Aarabi, Fayezeh, Alseekh, Saleh, Wybouw, Brecht, Van Der Kelen, Katrien, Nikkanen, Lauri, Krasensky-Wrzaczek, Julia, Sipari, Nina, Keinänen, Markku, Tyystjärvi, Esa, Rintamäki, Eevi, De Rybel, Bert, Salojärvi, Jarkko, Van Breusegem, Frank, Brosché, Mikael, Permi, Perttu, Aro, Eva-Mari, Wrzaczek, Michael, Kangasjärvi, Jaakko

“…ROS alter the abundance, thiol redox state and oligomerization of the RCD1 protein in vivo, providing feedback control on its function. …”
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Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications by Zhang, Simin

“…Using chemical crosslinking and immunofluorescence staining, in Paper II we could show that the S protein MPER could oligomerize and further heteromerize with the N-terminal internal fusion peptide (IFP). …”
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Biomolecular engineering of a human beta defensin model for increased salt resistance by Li, Xiang, Saravanan, Rathi, Kwak, Sang Kyu, Leong, Susanna Su Jan

“…The mutant hBD28 did not exhibit obvious differences with respect to hydrophobicity, oligomerization ability, and secondary structure compared to the wild type peptide. …”
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Viral proteases activate the CARD8 inflammasome in the human cardiovascular system by Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q. E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Michelle Yiyun, Zhang, Lyanne Yizhuo, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena

“…Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing protein family (NLRs) are intracellular pattern recognition receptors that mediate innate immunity against infections. …”
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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Lotz, R, Osterburg, C, Chaikuad, A, Weber, S, Akutsu, M, Machel, AC, Beyer, U, Gebel, J, Löhr, F, Knapp, S, Dobbelstein, M, Lu, X, Dötsch, V

“…Here we characterize the interaction of iASPP with p63 and show that it binds to the linker region between the DNA binding domain and the oligomerization domain. We further demonstrate that this binding site is removed in a splice variant of p63 where a stretch of five amino acids is replaced with a single alanine residue. …”

Structural and biochemical mechanisms of NLRP1 inhibition by DPP9 by Huang, Menghang, Zhang, Xiaoxiao, Toh, Gee Ann, Gong, Qin, Wang, Jia, Han, Zhifu, Wu, Bin, Zhong, Franklin, Chai, Jijie

“…Formation of the complex prevents UPA-mediated higher-order oligomerization of UPA-CARD fragments and strengthens ZU5-mediated NLRP1 autoinhibition. …”
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Synthesis and characterization of a novel azido fluoroalkyl oligoether energetic plasticizer by Ong, Yew Jin, Pisharath, Sreekumar, See, Anders Yang Feng, Tay, Chor Yong, Hng, Huey Hoon

“…In this study, we report a novel hybrid oligomer containing fluoroalkyl and azido moieties, 1,4-bis((2-azido-4,4,5,5,6,6,7,7,7-nonafluoroheptyl)oxy)butane (BANFHOB) as an energetic plasticizer for a cast curable fluoropolymer (FP) binder. …”
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High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5 by Liu, Chuan-Fa, Zheng, Jie, Yong, Hui Yee, Panutdaporn, Nantika, Tang, Kai, Luo, Dahai

“…We also present a high-resolution protein surface mapping technique that refines the cooperative oligomerization model of neighboring MDA5 molecules on long duplex RNA. …”
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Metal-organic framework-based nanovaccine for relieving immunosuppressive tumors via hindering efferocytosis of macrophages and promoting pyroptosis and cuproptosis of cancer cells by Liu, Yang, Niu, Rui, Zhang, Xiaodong, Zhang, Bin, Chen, Xiaokai, Guo, Jingjing, Song, Shuyan, Wang, Yinghui, Zhang, Hongjie, Zhao, Yanli

“…Meanwhile, Cu-THBQ/AX can also induce the oligomerization of dihydrolipoamide S-acetyltransferase to trigger tumor cell cuproptosis. …”
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Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

“…In addition, adiponectin protein levels increased significantly from Day 5 of differentiation with altered assembly of adiponectin oligomer.</p> <p>CRISPR/Cas9 germline knockout of Arl15 showed that homozygous KO mice die postnatally due to a complete cleft palate while heterozygous KO female mice have reduced fat mass on a normal diet. …”

Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein by Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James Pingkwan

“…Peptide C6 containing the Cluster I consensus sequence was shown to oligomerize and form amyloid-like fibrils. Taking advantage of this, C6 was further applied to detect the S protein expression in vitro by fluorescence staining. …”
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Single-site nanozymes with a highly conjugated coordination structure for antitumor immunotherapy via cuproptosis and cascade-enhanced T lymphocyte activity by Liu, Yang, Niu, Rui, Zhao, Huan, Wang, Yinghui, Song, Shuyan, Zhang, Hongjie, Zhao, Yanli

“…This surge of reactive oxygen species (ROS) leads to impaired mitochondrial function and insufficient ATP supply, impacting the function of copper-transporting ATPase-1 and causing dihydrolipoamide S-acetyltransferase oligomerization-mediated cuproptosis. Moreover, multiple ROS storms and glutathione peroxidase 4 depletion also induce lipid peroxidation and trigger ferroptosis. …”
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