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161
Engineering protein theranostics using bio-orthogonal asparaginyl peptide ligases
Published 2021“…Ideally, conventional recombinant proteins should be used as starting materials for modification with the desired detection and therapeutic functionalities, but simple chemical strategies that allow the introduction of two different modifications into a protein in a site-specific manner are not currently available. …”
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Journal Article -
162
Synthesis and development of novel small molecule inhibitors of nucleophilic hydrolases
Published 2024Subjects:Thesis -
163
Streamlined security framework for defence against XSS attacks targeted at HTML5
Published 2012“…While HTML5 is still undergoing mainstream adoption, web applications that incorporate HTML5 features such as the enhanced communication between origins in both server and client have become more vulnerable to pervasive browser-based attacks such as cross-site scripting (XSS), cross-site forgery (CSRF) and SQL Injection. …”
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Final Year Project (FYP) -
164
Behaviorally informed digital campaigns and their association with social media engagement and COVID-19 vaccine uptake in Belize
Published 2024“…However, lack of trust in the vaccine and fear of side effects in regions like the Caribbean resulted in a low uptake despite enough vaccine supply. …”
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Article -
165
Evaluation of soil parameters for the design of bored piles in residual soils
Published 2011“…The goal of this project is to provide a better characterization of side and base resistance for the design of bored piles in residual soils. …”
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Final Year Project (FYP) -
166
Homologous Lympho-epithelial Kazal-type inhibitor domains delay blood coagulation by inhibiting factor X and XI with differential specificity
Published 2020“…Nuclear magnetic resonance structural and dynamic experiments plus molecular dynamics simulation revealed that LEKTI domain 4 has enhanced backbone flexibility at the reactive-site loop. A model of the LEKTI-protease complex revealed that FXaB has a narrower S4 pocket compared with FXIa and hence prefers only small side-chain residues at the P4 position, such as Ala in LEKTI domain 6. …”
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Journal Article -
167
21A.215 Medical Anthropology, Fall 2004
Published 2004“…Analysis of medical practice as a cultural system, focusing on the human, as opposed to the biological, side of things. Also, examines how we and people in other cultures think of disease, health, body, and mind.…”
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Learning Object -
168
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169
Structural basis of RNA binding by leucine zipper GCN4
Published 2013“…Solution NMR experiments showed that the LZ-RNA interaction interface is located in the first two heptads of LZ moiety, and that only the dimeric (coiled coil) LZ conformation is capable of binding RNA. Site-directed mutagenesis of the LZ-GCN4 RNA binding interface showed that substrate binding is facilitated by lysine and arginine side chains, and that at least one nucleophilic residue is located in proximity to the RNA phosphate backbone. …”
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Journal Article -
170
A Wurster-type covalent organic framework with internal electron transfer-enhanced catalytic capacity for tumor therapy
Published 2024“…Furthermore, MSA-2 is specifically released in response to ROS at the tumor site, minimizing the off-target side effects. More importantly, Co-TB COF-induced STING activation normalizes tumor vasculature and increases the expression of endothelial T cell adhesion molecules, which greatly enhance the infiltration and function of effector T cells. …”
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Journal Article -
171
Understanding the molecular mechanism of ion and amino acid transport in neurons
Published 2020“…I report two novel inhibitor binding modes, expanding the current knowledge of the substrate binding site and how small molecules inhibitors interact with this site within the SLC1 family. …”
Thesis -
172
Si photocathode with Ag-supported dendritic Cu catalyst for CO2 reduction
Published 2020“…Selective carrier collection was accomplished by a p+ implantation on the illumination side and an n+ implantation followed by atomic layer deposition of TiO2 on the electrolyte site. …”
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Journal Article -
173
Cool surface as urban heat island effect mitigation strategy for tropical climate
Published 2021“…The experimental investigation is extended to a real-scale field experiment involving two side-by-side street canyons at an industrial site in Singapore. …”
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Thesis-Doctor of Philosophy -
174
21A.215 Medical Anthropology: Culture, Society, and Ethics in Disease and Health, Fall 2008
Published 2008“…This course looks at medicine from a cross-cultural perspective, focusing on the human, as opposed to biological, side of things. Students learn how to analyze various kinds of medical practice as cultural systems. …”
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Learning Object -
175
A machine learning approach on past ADS-B data to predict planning controller’s actions
Published 2021“…The en-route sector is usually managed by a team of two air traffic controllers: planning controller (D-side) and executive controller (R-side). The D-side controller is responsible for processing flight plan information to plan and organize the flow of traffic entering the sector. …”
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Conference Paper -
176
Smart nanomicelles with bacterial infection-responsive disassembly for selective antimicrobial applications
Published 2021“…We synthesized a cationic chitosan derivative and an anionic chitosan derivative – specifically an α-poly(L)lysine side-grafted chitosan (CS-PLL) and an anionic citraconyl anhydride (CA) modified polylysine side graft for chitosan (CS-PLL-CA). …”
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Journal Article -
177
Investigating viral glycosylation pathways for drug and vaccine development
Published 2021“…Chapter 4 focuses on the site-specific glycosylation occupancy, and N- and O-glycan structures attached to virion derived SARS-CoV-2 spike glycoproteins. …”
Thesis -
178
Model predictive control for integrated control of air-conditioning and mechanical ventilation, lighting and shading systems
Published 2022“…The MPC system was implemented in a test facility having two identical, side-by-side experimental cells to facilitate comparison with a building management system (BMS) employing conventional reactive feedback control. …”
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Journal Article -
179
Designing Microporous Polymers for Separations
Published 2025“…In Chapter 1, we investigate the influence of side-chain length and dispersity in ring-opening metathesis polymerization (ROMP) polymers with pore-generating side chains. …”
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Thesis -
180
An Algorithm Model for Solving the Single-Period Inventory Transportation Problems in the Construction Industry
Published 2020“…The problem is to identify what is the delivery quantities to the construction sites, what is delivery times and which routes should be used to deliver products to the customers at the construction site for the single-period deterministic inventory routing problem (SP-DIRP) in the construction sector. …”
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Article