Site-specific chemical and topological modifications to augment mRNA therapeutic potential by Aditham, Abhishek J.

“…We investigated the site-specific installation of chemical and topological modifications into therapeutic mRNA to augment their expression in cell cultures and mouse models. …”
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Decoding Codon Bias: The Role of tRNA Modifications in Tissue-Specific Translation by Ando, Daisuke, Rashad, Sherif, Begley, Thomas J., Endo, Hidenori, Aoki, Masashi, Dedon, Peter C., Niizuma, Kuniyasu

“…These data show that understanding tRNA modification enrichments across tissues is not only essential for understanding codon decoding and bias but can also be utilized for optimizing gene and mRNA therapeutics to be more tissue-, cell-, or condition-specific.…”
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Site-specific protein modifications by an engineered asparaginyl endopeptidase from Viola canadensis by Chen, Yu, Zhang, Dingpeng, Zhang, Xiaohong, Wang, Zhen, Liu, Chuan-Fa, Tam, James P.

“…This ligase activity can be used for site-specific protein modifications in biochemical and biotechnological applications. …”
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Specification mining for digital circuits by Lim, Zhi Xian

“…However, manually creating a complete set of formal properties is difficult and time-consuming process. Thus, specification mining approach for digital circuit has been proposed to automatically generate the formal specification. …”
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Mapping epigenetic modifications by sequencing technologies by Chen, X, Xu, H, Shu, X, Song, C-X

“…With the rapid development of sequencing technologies, scientists are able to detect specific epigenetic modifications with various quantitative, high-resolution, whole-genome/transcriptome approaches. …”

Surface modification and characterization of polypropylene fibers by Tan, Terry Jian Hong.

“…This surface modification comes with physical etching of the surface as well as alterations to the chemical characteristics of the fiber surface. …”
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Bio-modification of sand for cement grouting by Ng, Samuel Joel Rui Ming

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Electrochemical modification of electrodes with metal nanoparticles by Mavrokefalos, C

“…The electrochemical activity of these materials was investigated in order firstly to expand the knowledge of diamond electrochemistry and secondly to establish an understanding of how the electrochemical modification with metal nanoparticles of core-shell structure impacts their electrochemical performance.…”

Elucidating the effects of DNA modification on transcription by Yavorska, O

“…<p>DNA modifications play important roles in genome function of vertebrates. 5-methylcytosine (mC) has been extensively studied over the last 50 years as the most common covalent DNA modification, present at roughly 70% of CpGs in the human genome. …”

What is formal verification without specifications? A survey on mining LTL specifications by Neider, D, Roy, R

“…Virtually all verification techniques using formal methods rely on the availability of a formal specification, which describes the design requirements precisely. …”

Specification and Verification of Strong Timing Isolation of Hardware Enclaves by Lau, Stella, Bourgeat, Thomas, Pit-Claudel, Cl?ment, Chlipala, Adam

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High-level specification and efficient implementation of pipelined circuits by Marinescu, M-C, Rinard, M

“…This approach combines a high-level, modular specification language with an efficient implementation. …”
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Direct specification of lymphatic endothelium from mesenchymal progenitors by Lupu, I, Grainger, DE, Kirschnick, N, Weischer, S, Zhao, E, Martinez-Corral, I, Schoofs, H, Vanhollebeke, M, Jones, G, Godwin, J, Forrow, A, Lahmann, I, Riley, PR, Zobel, T, Alitalo, K, Mäkinen, T, Kiefer, F, Stone, OA

“…Collectively, this work establishes a cellular blueprint for LEC specification and indicates that discrete pools of mesenchymal progenitors can give rise to specialized subtypes of ECs.…”

Role of posttranslational modifications of histone proteins in epigenetics by Raj, R

“…<p>Nature has evolved an additional level of genetic regulation by-passing direct changes in genetic code through the means of posttranslational modifications (PTMs) of nucleobases and histone proteins. …”

The mean specific gravity of the earth by Henck, J. B.

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On-the-fly specific person retrieval by Parkhi, OM, Vedaldi, A, Zisserman, A

Specification and Planning of UAV Missions: A Process Algebra Approach by Karaman, Sertac, Rasmussen, Steven, Kingston, Derek, Frazzoli, Emilio

“…Formal languages have recently come under attention as a powerful tool to describe in a precise and rigorous way mission specifications (i.e., mission objectives and constraints) for robotic systems, and to design planning and control algorithms that provably achieve the specifications. …”
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Model reduction and stochastic analysis of the histone modification circuit by Bruno, Simone, Williams, Ruth J., Del Vecchio, Domitilla

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Residual soil modification using ureolytic bacteria and lime / by Low, Yee Hwa 1991-, author 644926, Khairul Anuar Kassim, supervisor 562339, Fakulti Kejuruteraan Awam 8022

Biophysical studies of oligonucleotides containing duplex stabilising modifications by Marafini, P

“…To enable easier access to this modification, a reductive amination labelling strategy was developed to produce pyrene-functionalised nucleobase analogues which allowed an easier synthesis of X-pyrene. …”