Alkynone β-trifluoroborates: a new class of amine-specific biocompatible click reagents by Teng, Shenghan, Ng, Elvis Wang Hei, Zhang, Zhenguo, Soon, Chee Ning, Xu, Hailun, Li, Ruifang, Hirao, Hajime, Loh, Teck-Peng

“…Unfortunately, despite the usefulness of this reaction, there are very few good amine-specific click methods reported thus far. Here, we report an amine-specific click reagent using alkynone β-trifluoroborates as the electrophiles. …”
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Are customers willing to pay for corporate social responsibility? A study of individual-specific mediators by Yuen, Kum Fai, Thai, Vinh V., Wong, Yiik Diew

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Specific maternal brain responses to their own child’s face : an fMRI meta-analysis by Rigo, Paola, Kim, Pilyoung, Esposito, Gianluca, Putnick, Diane L., Venuti, Paola, Bornstein, Marc H.

“…This meta-analysis aims to identify specific neural regions associated with “own child” compared to “other child”. …”
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Defining proteoform-specific interactions for drug targeting in a native cell signalling environment by Lutomski, CA, Bennett, JL, El-Baba, TJ, Wu, D, Hinkle, JD, Burnap, SA, Liko, I, Mullen, C, Syka, JEP, Struwe, WB, Robinson, CV

“…Subsequent isolation and dissociation by infrared multiphoton dissociation enabled the sequencing of individual retina proteoforms. Specifically, we categorized distinct proteoforms of rhodopsin, localized labile palmitoylations, discovered a Gβγ proteoform that abolishes membrane association and defined lipid modifications on G proteins that influence their assembly. …”

Site-level variation in parrotfish grazing and bioerosion as a function of species-specific feeding metrics by Lange, Ines D., Perry, Chris T., Morgan, Kyle Meredith, Roche, Ronan, Benkwitt, Cassandra E., Graham, Nicholas A. J.

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The influence of the dynamic change of fear: how gender-specific messages affect anti-smoking intentions by Gu, Rui

“…Keywords: fear appeal, the drive model, gender-specific, graphic warning labels, anti-smoking…”
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Small but prospective: development of enzyme-responsive small molecule fluorescent probes for specific bacterial imaging by Yan, Evelias Hui Xin

“…Among the numerous types of small-molecule fluorescence probes, the enzymatic responsive probes have been one that researchers are particularly interested in as such probes were reported to possess great specificity and high signal to noise ratio. Furthermore, bacterial enzymes are found to be closely related to the invasion of host immune system, which makes them a viable target to establish enzyme-activated fluorescent probes for specific bacterial imaging. …”
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Comparative effects of domain-specific human monoclonal antibodies against LGI1 on neuronal excitability by Sell, J, Rahmati, V, Kempfer, M, Irani, SR, Ritzau-Jost, A, Hallermann, S, Geis, C

“…LRR- and EPTP-specific effects were evaluated by patch-clamp recordings in cultured hippocampal neurons and compared with biophysical neuron modeling. …”

Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals by Vavoulis, DV, Cutts, A, Thota, N, Brown, J, Sugar, R, Rueda, A, Ardalan, A, Howard, K, Matos Santo, F, Sannasiddappa, T, Miller, B, Ash, S, Liu, Y, Song, C, Nicholson, BD, Dreau, H, Tregidgo, C, Schuh, A

“…We conduct a diagnostic accuracy study across multiple cancer types in symptomatic patients, achieving 94.9% sensitivity and 88.8% specificity. Matched tumour biopsies are used for validation, not for guiding the analysis, imitating an early detection scenario. …”

In vivo enhancement of tumour-specific T cells via peptide–MHC-pseudotyped retroviral gene delivery by Kwong, H, Borrow, P

Improving social sustainability through context-specific mixed-use high-rise apartments in tiong nam / by Elaine, Lee Mei Lian, 1989-, author 610717, Tareef Hayat Khan, supervisor 604967, Syed Ahmad Iskandar Syed Ariffin, supervisor 643448, Fakulti Alam Bina 8041

Improving social sustainability through context-specific mixed-use high-rise apartments in tiong nam / by Elaine, Lee Mei Lian, 1989-, author 610717

Strain-specific parallel evolution drives short-term diversification during Pseudomonas aeruginosa biofilm formation by McElroy, Kerensa E., Hui, Janice G. K., Woo, Jerry K. K., Luk, Alison W. S., Webb, Jeremy S., Kjelleberg, Staffan, Rice, Scott A., Thomas, Torsten

“…Mutations were found to be strain specific: the mucoid strain 18A experienced mutations in alginate production genes and a c-di-GMP regulator gene; while PA01 acquired mutations in PilT and PilY1, possibly in response to a rapid expansion of a lytic Pf4 bacteriophage, which may use type IV pili for infection. …”
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Discovery of glucose-specific, peptide-based carbohydrate mimics using phage displayed random peptide libraries. by Yu, Limin.

“…Phage displayed random peptide libraries were used to discover peptides which functionally mimic the monosaccharide glucose by screening these libraries against glucose-specific lectins. Although the screening of phage display libraries against single lectins has been previously reported, debate exists whether the resulting peptides are indeed true sugar mimics or merely act as ligands for the targeted lectin. …”
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Distilling crowd knowledge from software-specific Q&A discussions for assisting developers’ knowledge search by Chen, Chunyang

“…In addition, the decay of information quality such as misspelling, inconsistency, and abuse of domain-specific abbreviations aggravates the search performance. …”
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Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket by Kannan, Srinivasaraghavan, Venkatachalam, Gireedhar, Lim, Hong Hwa, Surana, Uttam, Verma, Chandra

“…Our study characterizes a druggable allosteric pocket which appears to be specific to certain oncogenic mutants of the EGFR and holds therapeutic potential.…”
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DNA extraction methodologies for ultra long nanopore sequencing to determine chromosome specific rodent telomere lengths by Kidd, Elliot, Mooruth, Ravi, Meimaridou, Eirini, Walley, Andrew, Fairbrother, Una

“…Direct sequencing of highly repetitive stretches of DNA is difficult, using specific DNA extraction techniques and adaptive sampling and tagging approaches for targeted enrichment has generated chromosome specific ultralong reads in rodents.…”
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An epitope-specific LGI1-autoantibody enhances neuronal excitability by modulating Kv1.1 channel by Extrémet, J, El Far, O, Ankri, N, Irani, SR, Debanne, D, Russier, M

“…Patient-derived recombinant monoclonal antibodies (mAbs) are ideal reagents to study whether domain-specific LGI1-autoantibodies induce epileptiform activities in neurons and their downstream mechanisms. …”

Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…To better understand ventricle-specific molecular changes influencing heart failure development, we first performed unbiased quantitative mass spectrometry on pre-mortem non-diseased human myocardium to compare the metabolome and proteome between the normal left and right ventricles. …”

Maternal Death Surveillance and Response in Sudan: an evidence-based, context-specific optimisation to improve maternal care by Altijani Osman Abbakar, N