Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs by Garcia-Guerra, A, Sathyaprakash, C, de Jong, O, Lim, W, Vader, P, El Andaloussi, S, Bath, J, Reine, J, Aoki, Y, Turberfield, A, Wood, MA, Rinaldi, C

“…By enabling RNA-controlled gene editing activity, this technology creates opportunities to advance tissue-specific CRISPR treatments for human diseases.…”

Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria by Gargiulo, L, Papaioannou, M, Sica, M, Talini, G, Chaidos, A, Richichi, B, Nikolaev, AV, Nativi, C, Layton, M, de la Fuente, J, Roberts, I, Luzzatto, L, Notaro, R, Karadimitris, A

“…Thus, a novel, autoreactive, CD1d-restricted, GPI-specific T-cell population, enriched in an invariant TCRα chain, is expanded in PNH patients and may be responsible for BMF in PNH.…”

The afterlife of site-specific sculpture: a self-referential study through practice by Kim, M

“…It explores issues related to site-specific sculpture and begins by examining my existing methods of site-specific sculptural intervention within the exhibition environment. …”

Wolbachia-mosquito interactions and engineered female-specific lethality for Aedes-arbovirus control by Molloy, JC

“…In Chapter 4, I engineer female-specific, late-acting lethality in <em>Ae. aegypti</em> using specific effectors crossed with candidate pupal-stage promoters and a <em>doublesex</em> cassette causing sexspecific splicing. …”

A clinical perspective on muscle specific kinase antibody positive myasthenia gravis by Keritam, O, Vincent, A, Zimprich, F, Cetin, H

“…The discovery of autoantibodies directed against muscle-specific kinase (MuSK) in “seronegative” myasthenia gravis (MG) patients marked a milestone in MG research. …”

Metabolomic fingerprints: seasonal and farm-specific differences in Heterotrigona itama bee bread by Shin, Siong Ng, Nurkhalida Kamal, Wan, Kiew-Lian, Izfa Riza Hazmi, Nurul Yuziana Mohd Yusof, Mohd Faizal Abu Bakar, Mohd Fahimee Jaapar, Norela Sulaiman, Fareed Sairi

“…In terms of temporal factors, the analysis highlights specific metabolites exclusive to the wet season, such as flavones and flavonoids. …”
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Alkynone β-trifluoroborates: a new class of amine-specific biocompatible click reagents by Teng, Shenghan, Ng, Elvis Wang Hei, Zhang, Zhenguo, Soon, Chee Ning, Xu, Hailun, Li, Ruifang, Hirao, Hajime, Loh, Teck-Peng

“…Unfortunately, despite the usefulness of this reaction, there are very few good amine-specific click methods reported thus far. Here, we report an amine-specific click reagent using alkynone β-trifluoroborates as the electrophiles. …”
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Distribution and abundance of human-specific bacteroides and relation to traditional indicators in an urban tropical catchment by Nshimyimana, J. P., Ekklesia, Eveline, Shanahan, P., Chua, L. H. C., Thompson, J. R.

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Radiation-induced grafting of glycidyl methacrylate onto natural cotton fibers and trimethylamine modification for p-nitrophenol adsorption by Saber, Shihab Ezzuldin M., Abdullah, Luqman Chuah, Ming Ting, Teo, Md Jamil, Siti Nurul Ain, Choong, Thomas S.Y., Abdulkareem -Alsultan, G.

“…The spontaneous and exothermic nature of adsorption was identified by thermodynamic analysis. Specifically, it is evident that adsorbent can be readily reproduced and recycled with no accompanying loss of adsorptive performance in the alkaline medium. …”

Modification of the interface between TiO2 and electrolyte toward higher efficiency dye sensitized solar cells by Wang, Xiu

“…This thesis is featured with two main approaches for improving the performance of DSSCs: a direct modification on TiO2 surface through surface treatment and molecular passivation and an indirect modification to alter the TiO2 surface charge through adding nanoparticles such as hydrotalcite and silica into the electrolyte. …”
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Defining proteoform-specific interactions for drug targeting in a native cell signalling environment by Lutomski, CA, Bennett, JL, El-Baba, TJ, Wu, D, Hinkle, JD, Burnap, SA, Liko, I, Mullen, C, Syka, JEP, Struwe, WB, Robinson, CV

“…Subsequent isolation and dissociation by infrared multiphoton dissociation enabled the sequencing of individual retina proteoforms. Specifically, we categorized distinct proteoforms of rhodopsin, localized labile palmitoylations, discovered a Gβγ proteoform that abolishes membrane association and defined lipid modifications on G proteins that influence their assembly. …”

Enzyme‐Triggered Intestine‐Specific Targeting Adhesive Platform for Universal Oral Drug Delivery by Li, Ying, Lee, Jung Seung, Kirtane, Ameya R., Li, Mengyuan, Coffey, Charles William, Hess, Kaitlyn, Lopes, Aaron, Collins, Joy, Tamang, Siddartha, Ishida, Keiko, Hayward, Alison, Wainer, Jacob, Wentworth, Adam J., Traverso, Giovanni

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Specificity and structural characterization of the PDZ domain from DegS, an extracytoplasmic E. coli protease by Walsh, Nathan P. (Nathan Peter), 1973-

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Zero-shot learning via category-specific visual-semantic mapping and label refinement by Niu, Li, Cai, Jianfei, Veeraraghavan, Ashok, Zhang, Liqing

“…Moreover, to avoid learning visual-semantic mapping for each unseen category in the large-scale classification task, we additionally propose a deep adaptive embedding model named deep AEZSL sharing the similar idea (i.e., visual-semantic mapping should be category specific and related to the semantic space) with AEZSL, which only needs to be trained once, but can be applied to arbitrary number of unseen categories. …”
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Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark by Alonso-Serra, Juan, Safronov, Omid, Lim, Kean-Jin, Fraser-Miller, Sara J., Blokhina, Olga B., Campilho, Ana, Chong, Sun-Li, Fagerstedt, Kurt, Haavikko, Raisa, Helariutta, Ykä, Immanen, Juha, Kangasjärvi, Jaakko, Kauppila, Tiina J., Lehtonen, Mari, Ragni, Laura, Rajaraman, Sitaram, Räsänen, Riikka-Marjaana, Safdari, Pezhman, Tenkanen, Maija, Yli-Kauhaluoma, Jari T., Teeri, Teemu H., Strachan, Clare J., Nieminen, Kaisa, Salojärvi, Jarkko

“…We identified multiple tissue-specific metabolic pathways, such as the mevalonate/betulin biosynthesis pathway, that displayed differential evolution within the Betulaceae. …”
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Genotype-specific expression and NLR repertoire contribute to phenotypic resistance diversity in Plantago lanceolata by Safdari, Pezhman, Höckerstedt, Layla, Brosche, Mikael, Salojärvi, Jarkko, Laine, Anna-Liisa

“…Molecular processes contributing to this variation in nature are still poorly known, although theory predicts resistance to evolve at specific loci driven by pathogen-imposed selection. …”
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New method for automatic generation of patient specific finite element models of the distal femur by Lek, Cheah Wen.

“…A new algorithm to automatically generate patient-specific FE models of human femur directly from magnetic resonance imaging (MRI) data is presented. …”
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Are customers willing to pay for corporate social responsibility? A study of individual-specific mediators by Yuen, Kum Fai, Thai, Vinh V., Wong, Yiik Diew

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Specific maternal brain responses to their own child’s face : an fMRI meta-analysis by Rigo, Paola, Kim, Pilyoung, Esposito, Gianluca, Putnick, Diane L., Venuti, Paola, Bornstein, Marc H.

“…This meta-analysis aims to identify specific neural regions associated with “own child” compared to “other child”. …”
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Understanding the conceptual framework of pad structural modification for disc brake squeal noise suppression based on system’s dynamic response. by Sulaiman, M. S., Abu Husain, N., Abu Bakar, A.R., Abdul Hamid, M. K., Ismail, N. H., Zakaria, K.

“…The system's dynamics response study is found adequate to explain the relationship of structural pad modification towards the brake squeal noise propensity. …”
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