Optimizing Cas9-mediated HDR in HEK293 by Lee, Cheryl

“…With its programmable guide RNA sequence for specific gene targeting, it allows for precise genome editing including substitutions, knock-outs, and knock-ins. …”
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Development of a light aircraft model for the NTU flight simulator by Lee, Kok Vui.

“…In order to validate the accuracy of the modifications, simulation flights were conducted and relevant data was extracted for comparison with theoretical values. …”
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Stability of peptide nucleic acid influenced by peptoid-like sidechains : MD simulation study. by Yeo, Sven Hwea Jie.

“…In this report, MD simulations of decamer heteroduplexes involving modified PNA were performed under periodic boundary conditions. Modifications are based on a recent work of Prof Liu’s lab, involving γ-N modification of PNA aeg backbone with amino-peptoid sidechain (APS) experimentally shown to retain its hybridisation affinity with DNA/RNA. …”
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The role of bacteriophages in an aerobic biogranulation system by A R Balamurugan

“…However, it was found that the original protocol, which involves heat treatment, was not suitable for the studying of the phage community in our systems. Therefore modifications will be made to the protocol in future studies to exclude this treatment. …”
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Development of an engine control module and dashboard display based on electric vehicle system by Low, Alex Boon Hwee

“…Along the design process, numerous changes have been made to incorporate new features such as conversion to a 4 seater sedan, inclusion of battery packs, wireless charging features and such. With the modifications involved, the original S2000 on board systems have to be revised and changed as accordingly. …”
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Effects of engine oil additives on engine performance and temperature by Law, Zheng Yi

“…How to get the engine efficiency as good as the new one without doing any hardware modifications? The answer is engine oil. Therefore, this project is to study the effects of different engine oils and engine oil additives on the fuel consumption rate and the engine temperature of the diesel engine, Perkins 103-10. …”
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Adaptive average arterial pressure control by multi-agent on-policy reinforcement learning by Hong, X, Ayadi, W, Alattas, KA, Mohammadzadeh, A, Salimi, M, Zhang, C

“…This approach enhances the adaptability of the controller by allowing for dynamic modifications to dosage and blood pressure control parameters. …”

A simplified formulation to estimate influence of gearbox parameters on the rattle noise by Zhang, Jidong, Sui, Wentao, Dhupia, Jaspreet

“…Thus, the proposed analytical evaluation method can optimize the gearbox specifications at the design stage to reduce the gear rattle noise level.…”
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Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm by Ng, Calista Keow Leng, Herath, Wishva, Lili, Sun, Hutchins, Andrew P, Robson, Paul, Kolatkar, Prasanna R, Stanton, Lawrence W, Aksoy, Irene, Jauch, Ralf, Chen, Jiaxuan, Dyla, Mateusz, Divakar, Ushashree, Bogu, Gireesh K, Teo, Roy

“…We demonstrate here that genomic redistribution of Oct4 by alternative partnering with Sox2 and Sox17 is a fundamental regulatory event of endodermal specification. We show that Sox17 partners with Oct4 and binds to a unique ‘compressed’ Sox/Oct motif that earmarks endodermal genes. …”
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Pentacyclic fused diborepinium ions with carbene- and carbone-mediated deep-blue to red emission by Hollister, Kimberly K, Molino, Andrew, Le, VuongVy V, Jones, Nula, Smith, Wyatt J, Müller, Peter, Dickie, Diane A, Wilson, David JD, Gilliard, Robert J

“…Designing molecules that can undergo late-stage modifications resulting in specific optical properties is useful for developing structure-function trends in materials, which ultimately advance optoelectronic applications. …”
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Structural case on adjuncts by Jou, Eunsun

“…I derive these patterns from a specific model of Voice, and a model of successive-cyclic Dependent Case. …”
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Post-fire cross-sectional behaviour of hot-rolled austenitic stainless steel channel section stub columns under combined compression and minor-axis bending by Li, Shuai, Zhao, Ou

“…The evaluation results revealed that the design interaction curves given in the European code and American specification led to rather conservative and scattered resistance predictions, which were attributed to the conservative end points and inefficient shapes. …”
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Generation mechanism and suppression measure of electromagnetic vibration in permanent magnet synchronous machine: a review by Zhu, Shengdao, Zhao, Wenxiang, Ji, Jinghua, Liu, Guohai, Lee, Christopher Ho Tin

“…The electromagnetic (EM) vibration performance is an important specification for the PMSM, as it affects the passenger’s riding comfort and the noise grade of electrified transportation. …”
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Modeling and optimization of building HVAC systems by Jin, Guang Yu

“…All the model parameters can be derived from manufacturers’ specification data or on-site testing and measurement data. …”
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Impact of peer review on reports of randomised trials published in open peer review journals : retrospective before and after study by Hopewell, S, Collins, G, Boutron, I, Yu, L, Cook, J, Shanyinde, M, Wharton, R, Shamseer, L, Altman, D

“…<br/><strong>Results:</strong> Of the 93 trial reports, 38% (n=35) did not describe the method of random sequence generation, 54% (n=50) concealment of allocation sequence, 50% (n=46) whether the study was blinded, 34% (n=32) the sample size calculation, 35% (n=33) specification of primary and secondary outcomes, 55% (n=51) results for the primary outcome, and 90% (n=84) details of the trial protocol. …”

Production protocols in the current practice of instilling traditional values in Malay kuih by Kamaruzaman, Mohd Yusof, Ab. Karim, Shahrim, Che Ishak, Farah Adibah, Arshad, Mohd Mursyid

“…With the findings of this study, the specification of the traditional Malay kuih can further be rekindled and expand on possibilities for its resurgence.…”
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Exploring Optoelectronic Properties of Twisted and Intercalated Niobium Oxide Dihalides by Luo, Ashley

“…2D materials, or layers of one-atom thick crystalline solids, offer a flexible solution for a variety of applications that require certain characteristics. As a result of modifications in physical and chemical design involving 2D materials such as stacking, twisting and ion intercalation, properties such as electrical conductivity, spin diffusion length, thermal conductivity, and mechanical strength observe more degrees of freedom than in their bulk material counterpart. …”
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Functional characterization of orexin system by Chua, Peiling

“…In conclusion, the cloning process should be continued so that we would be able to conduct experiments to elucidate orexin’s antidepressant-like effects and perhaps the different effects brought by both orexin receptors. Also, more modifications should be done to the forced swimming test experiments in order to generate a good behavioral paradigm.…”
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Change method signature refactoring plug-in for eclipse C/C++ development tooling by Le, Truc Viet.

“…The plug-in is able to generate the desirable modifications to the source code. However, minor shortcomings do exist in terms of user interface and complex refactorings. …”
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Effect of queuing and priority rules in semiconductor testing workstation by Hadi, Ferdinand

“…Several modeling modifications are needed to obtain the best output. Therefore, optimization in the system can be carried out. …”
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