Enhancing the photo-electrocatalytic properties of g-C3N4 by boron doping and ZIF-8 hybridization by Atta, Mahmood Riyadh, Maizatul Shima, Shaharun, Khan, Maksudur Rahman Md, Bawadi, Abdullah, Al-Mahmodi, Akram Fadhl, Nur Diyan, Mohd Ridzuan, Munusamy, Thurga Devi, Jun Wei, Lim

“…As a result, merging these modifications noticeably enhanced the photo-electrocatalytic activity and light sensitivity of the main catalyst, which opens a wider range of applications and future research.…”
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Cryogelation of human hair keratins by Chua, Huei Min

“…Nonetheless, conventional methods to translate HHK proteins into meaningful three-dimensional (3D) constructs often require chemical modifications or cross-linking additives. Such processing routes can be complicated and may compromise the resultant biocompatibility of the scaffolds. …”
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Information retrieval and multimodal sentiment analysis for climate change by Duong, Cuc Thi Kim

“…The Intergovernmental Panel on Climate Change (IPCC) has affirmed that human activities persist in elevating the global mean temperature, altering extreme weather patterns like heatwaves, droughts, tropical cyclones, and heavy rainfall. These climatic modifications pose significant economic and social threats if not promptly and effectively addressed. …”
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MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors by Kim, HaEun, Lebeau, Benjamin, Papadopoli, David, Jovanovic, Predrag, Russo, Mariana, Avizonis, Daina, Morita, Masahiro, Afzali, Farzaneh, Ursini-Siegel, Josie, Postovit, Lynne-Marie, Witcher, Michael, Topisirovic, Ivan

“…However, the relationship between the mechanistic target of rapamycin (mTOR), which is a pivotal metabolic regulator, and epigenetic modifications remains poorly understood. Our results show that mTORC1 activation caused by the abrogation of its negative regulator tuberous sclerosis complex 2 (TSC2) coincides with increased levels of the histone modification H3K27me3 but not H3K4me3 or H3K9me3. …”
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Structural and functional studies of C-nucleoside formation enzymes by Li, W

“…In the 20th century, industrialisation and scientific knowledge saw a boom in active single compounds isolated from nature and used to treat disease directly or after relatively minor chemical modification. However, by the end of the 20th century this approach had fallen out from favour. …”

Part I Targeting RNA duplexes with modified triplex-forming oligonucleotides Part II Allostery within a Watson-Crick RNA duplex and its application in studying RNA recognition by R... by Zhou, Yuan

“…UV-absorbance-detected thermal melting studies reveal that the LNA and 2-thio U modifications in TFOs strongly enhance triplex formation with both parental RNA and DNA duplex regions. …”
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Space charge induced beam loss on a high intensity proton synchrotron by Pine, B

“…One such feature is the conformal rectangular vacuum vessel, which takes the shape of the design beam envelope with certain modifications. This vacuum vessel has a complex effect on beam image fields.…”

Evaluation of keratin templates on dermal regeneration of full-thickness burns by Moay, Zi Kuang

“…All in all, HHK foams are capable as dermal substitutes to treat full-thickness burn wounds through promoting earlier angiogenesis in the surrounding tissue, though it would require further modifications to improve its potential of being an ideal dermal substitute.…”
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Development of high-affinity peptide-drug conjugates for investigating the TRIM24 PHD and bromodomain by Platt, MA

“…<p>Tripartite motif-containing protein 24 (TRIM24) is an epigenetic transcriptional regulator involved in reading histone 3 (H3) methylated (KMe_<em>x</em>) and acetylated (KAc) lysine post-translational modifications (PTMs) through an adjacent plant homeodomain-bromodomain (PHD-BRD) cassette, respectively. …”

Studies of insulin transport across intestinal epithelium using nano-encapsulation for oral delivery by Zhang, Yiming

“…The studies of insulin transport across intestinal epithelial cells were investigated from three general areas; interaction of empty liposomes with intestinal epithelial Caco-2 cells, cellular interaction and transport of insulin loaded liposomes with appropriated surface modifications across Caco-2 cells, loading of insulin onto surface of liposomes for enhanced transport, improved loading, and sustained release. …”
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Priorities to inform research on marine plastic pollution in Southeast Asia by Omeyer, Lucy C. M., Duncan, Emily M., Aiemsomboon, Kornrawee, Beaumont, Nicola, Bureekul, Sujaree, Cao, Bin, Carrasco, Luis R., Chavanich, Suchana, Clark, James R., Cordova, Muhammad R., Couceiro, Fay, Cragg, Simon M., Dickson, Neil, Failler, Pierre, Ferraro, Gianluca, Fletcher, Stephen, Fong, Jenny, Ford, Alex T., Gutierrez, Tony, Shahul Hamid, Fauziah, Hiddink, Jan G., Hoa, Pham T., Holland, Sophie I., Jones, Lowenna, Jones, Nia H., Koldewey, Heather, Lauro, Federico M., Lee, Charlotte, Lewis, Matt, Marks, Danny, Matallana-Surget, Sabine, Mayorga-Adame, Claudia G., McGeehan, John, Messer, Lauren F., Michie, Laura, Miller, Michelle A., Mohamad, Zeeda F., Nor, Nur Hazimah Mohamed, Müller, Moritz, Neill, Simon P., Nelms, Sarah E., Onda, Deo Florence L., Ong, Joyce J. L., Pariatamby, Agamuthu, Phang, Sui C., Quilliam, Richard, Robins, Peter E., Salta, Maria, Sartimbul, Aida, Shakuto, Shiori, Skov, Martin W., Taboada, Evelyn B., Todd, Peter A., Toh, Tai Chong, Valiyaveettil, Suresh, Viyakarn, Voranop, Wonnapinij, Passorn, Wood, Louisa E., Yong, Clara L. X., Godley, Brendan J.

“…Using an inductive method, 21 research questions emerged under five non-predefined key themes, grouping them according to which: (1) characterise marine plastic pollution in Southeast Asia; (2) explore its movement and fate across the region; (3) describe the biological and chemical modifications marine plastic pollution undergoes; (4) detail its environmental, social, and economic impacts; and, finally, (5) target regional policies and possible solutions. …”
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AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

“…We show that the molecules selected by the AtomNet® model are novel drug-like scaffolds rather than minor modifications to known bioactive compounds. Our empirical results suggest that computational methods can substantially replace HTS as the first step of small-molecule drug discovery.…”
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Strategies to modulate Amorphous Oxide Semiconductor properties for low temperature transparent transistors by Kulkarni, Mohit Rameshchandra

“…Another method for selective on-demand modification of TFT properties using chemical surface treatment was also explored in the dissertation. …”
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HiPIMS deposition of VO2 thermochromic coating for enhanced optical properties by Vu, Tuan Duc

“…The optimal deposition parameters and the appropriate substrate and process modifications are ascertained with the goal of improving VO2 thermochromism, optical modulation, and service life.…”
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Information fusion and cooperative control for target search and localization in multi-agent sensor networks by Hu, Jinwen

“…The optimal sensing strategy is further compared with other sensing strategies using different optimization criteria such as the Cramer-Rao lower bound. Possible modifications of the proposed optimal sensing strategy are also discussed. …”
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Reduced semiconductor energy conversion systems. by Zhang, Lei.

“…To gain further improvements, modifications to the basic converter topology must be done, where one possible area is to generate more than two switching levels per phase. …”
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Genetic and molecular characterisation of non-tissue culture adapted influenza B viruses detected in Singapore between 2004-2009 by Muhammad Raihan Jumat

“…SDS-PAGE analysis reveal that both these proteins are modified by the cell and further elucidation is required to determine the kinetics and the function of these modifications. The bulk of the work presented in this thesis revolves around the molecular characterisation of the influenza B NS1 protein. …”
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Human learning principles inspired particle swarm optimization algorithms by Muhammad Rizwan Tanweer

“…The limitations associated with PSO have been extensively studied and different modifications, variations and refinements to PSO have been proposed in the literature for enhancing its performance. …”
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo... by Liu, Fang

“…The detection mechanism of our rational design is mainly based on the fact that the specific interactions between LPS and neutralizing peptide could break up the π-π stacking conformation of neighbouring PDI molecules on Fe3O4@SiO2 nanoparticle surfaces, and thus efficiently turn on the self-quenched fluorescence. …”
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The effects of atmosphere-ocean-wave coupling during tropical cyclone by Garg, Nikhil

“…In addition to the coupling interface, the modelling system also includes several modules and modifications for including effects of processes such as sea spray and ocean currents. …”
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