Developing small molecule ligands for the study of bromodomain-histone interactions by Brand, M

“…The histone code refers to different combinations of epigenetic marks, each mediating transcription in a specific manner. Bromodomains are acetyl-lysine readers of the histone protein which interact selectively with acetylated lysine residues on histones. …”

Integration of genetic data and genomic annotation in the analysis of genome wide association studies by Ng, E

“…Some of these associations were cell specific and/or context specific. Many of these CNVs contained SNPs which are lead SNPs in GWAS studies on a variety of different phenotypes.…”

Transcriptomics of manually isolated Amborella trichopoda egg apparatus cells by Flores-Tornero, María, Proost, Sebastian, Mutwil, Marek, Scutt, Charles P., Dresselhaus, Thomas, Sprunck, Stefanie

“…Our transcriptomics data revealed Amborella-specific genes and genes conserved in eudicots and monocots. …”
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Smart notification system for nursing homes by Yap, Jovin Kuang Yong

“…Secondly, various works specific to facilitating the day-to-day duty were also implemented. …”
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Spouse and partner immigration to the United Kingdom: history and current issues in British immigration policy by Hutton, J

“…</li> </ul> <p>More specifically, this project is intended to provide a comparative empirical analysis and theoretical explanations of the subject. …”

Communication in the workplace: request mitigations in Instant Messaging (IM) among native Malay speakers by Petani Mohd Noor, Marlyna Maros, Kesumawati Abu Bakar, Normalis Amzah

“…One effective strategy is using external modifications or supportive moves to mitigate requests. …”
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CPU availability predictor and machine recommender for a desktop grid by Shafazand, Mohammad Yaser

“…Many have successfully researched on processes, techniques and methodologies for accurate resource availability predictions in grid computing, but only some have specifically considered the desktop grid. The overhead of the predictor systems in these environments are also less studied. …”
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Exploring Optoelectronic Properties of Twisted and Intercalated Niobium Oxide Dihalides by Luo, Ashley

“…2D materials, or layers of one-atom thick crystalline solids, offer a flexible solution for a variety of applications that require certain characteristics. As a result of modifications in physical and chemical design involving 2D materials such as stacking, twisting and ion intercalation, properties such as electrical conductivity, spin diffusion length, thermal conductivity, and mechanical strength observe more degrees of freedom than in their bulk material counterpart. …”
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Functional characterization of orexin system by Chua, Peiling

“…In conclusion, the cloning process should be continued so that we would be able to conduct experiments to elucidate orexin’s antidepressant-like effects and perhaps the different effects brought by both orexin receptors. Also, more modifications should be done to the forced swimming test experiments in order to generate a good behavioral paradigm.…”
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Change method signature refactoring plug-in for eclipse C/C++ development tooling by Le, Truc Viet.

“…The plug-in is able to generate the desirable modifications to the source code. However, minor shortcomings do exist in terms of user interface and complex refactorings. …”
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Effect of queuing and priority rules in semiconductor testing workstation by Hadi, Ferdinand

“…Several modeling modifications are needed to obtain the best output. Therefore, optimization in the system can be carried out. …”
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Development of an inducible single lentiviral vector-based microRNA knockdown construct. by Ip, Jun Yu.

“…The current limitation in studying the biological functions of miRNAs lie in the lack of an inducible system that conditionally knockdown miRNA expression. With some modifications of a previously described inducible system that repress gene expression, we developed a lentivector-based, conditional gene expression system for drug-controllable expression of antimiRs, using miR-138 as our model of study. …”
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Characterization of sarcomeric protein changes during mouse heart failure progression by Lam, Do Thuy Uyen Ha

“…Following an MI event, the heart undergoes extensive remodelling where there is modification to the proteins especially the sarcomeric proteins responsible for the contractility function in cardiomyocytes. …”
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Stem cell genome-to-systems biology by Chia, Na Yu, Ng, Huck-Hui

“…With the elucidation of protein–protein interaction, protein–DNA regulation, microRNA involvement as well as the epigenetic modifications, it is possible to comprehend the defining features of stem cells at the system level.…”
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Evoked resonant neural activity long-term dynamics can be reproduced by a computational model with vesicle depletion by Sermon, JJ, Wiest, C, Tan, H, Denison, T, Duchet, B

“…We make biophysically-motivated modifications to the Kuramoto model and fit its parameters to the slow dynamics of ERNA obtained from data. …”

Non-uniform deblurring for shaken images by Whyte, O, Sivic, J, Zisserman, A, Ponce, J

“…This model is able to capture non-uniform blur in an image due to camera shake using a single global descriptor, and can be substituted into existing deblurring algorithms with only small modifications. To demonstrate its effectiveness, we apply this model to two deblurring problems; first, the case where a single blurry image is available, for which we examine both an approximate marginalization approach and a maximum a posteriori approach, and second, the case where a sharp but noisy image of the scene is available in addition to the blurry image. …”

Flexural-torsional buckling behaviour and resistances of fixed-ended press-braked S690 high strength steel angle section columns by Zhang, Lulu, Liang, Yating, Zhao, Ou

“…The obtained test and numerical data were then used to evaluate the accuracy of the relevant codified design rules, given in the European code, North American specification and Australian/New Zealand standard, and a recently proposed DSM-based design approach. …”
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Association between a selective 5-HT4 receptor agonist and incidence of major depressive disorder: emulated target trial by de Cates, AN, Harmer, CJ, Harrison, PJ, Cowen, PJ, Emmanuel, A, Travis, S, Murphy, SE, Taquet, M

“…Robustness of the results to changes in model and population specification was tested. Secondary outcomes included a first diagnosis of six other neuropsychiatric disorders. …”

Does belief in supernatural agents moderate the association between interpersonal conflict at work and worker well-being? by Jung, Jong Hyun, Choi, Gayoung, Ang, Shannon

“…In addition, belief in angelic intervention and belief in supernatural evil moderate the association. Specifically, the positive association between interpersonal conflict at work and anxiety is weaker for those who report the belief in angelic intervention. …”
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Medical informatics in medical research - the Severe Malaria in African Children (SMAC) Network's experience by Olola, CHO, Missinou, MA, Issifou, S, Anane-Sarpong, E, Abubakar, I, Gandi, JN, Chagomerana, M, Pinder, M, Agbenyega, T, Kremsner, PG, Newton, CRJC, Wypij, D, Taylor, TE

“…After prototyping, relational database management systems were implemented for data entry and verification, data submission and quality assurance monitoring.…”