A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling by Deng, H, Zhang, J, Wang, Y, Joshi, D, Pi, X, De Val, S, Schwartz, MA

“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. …”

Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging by Jakobsen, NA, Turkalj, S, Zeng, AGX, Stoilova, B, Metzner, M, Rahmig, S, Nagree, MS, Shah, S, Moore, R, Usukhbayar, B, Angulo Salazar, M, Gafencu, G-A, Kennedy, A, Newman, S, Kendrick, BJL, Taylor, AH, Afinowi-Luitz, R, Gundle, R, Watkins, B, Wheway, K, Beazley, D, Murison, A, Aguilar-Navarro, AG, Flores-Figueroa, E, Dakin, SG, Carr, AJ, Nerlov, C, Dick, JE, Xie, SZ, Vyas, P

“…To gain insight into how CH mutations enable gradual clonal expansion, we used single-cell multi-omics with high-fidelity genotyping on human CH bone marrow (BM) samples. Most of the selective advantage of mutant cells occurs within HSCs. …”

3.3–4.3 GHz efficient continuous class-F gallium nitride power amplifier based on simplified real frequency technique and harmonic tuning by Sadeque, Golam, Yusoff, Zubaida, Roslee, Mardeni, Hashim, Shaiful Jahari, Mohd Marzuki, Azah Syafiah, Lees, Jonathan, Zubir, Farid, Al-Bawri, Samir Salem

“…The linearity of the RFPA with a two-tone signal is measured and the value is less than -22 dBc all over the band. © 2024 Sadeque et al. …”
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Optimisation of stamp compliance for nanoimprint lithography : an experimental and simulation investigation of deformation of Polydimethylsiloxane (PDMS) and Ultraviolet Curable Po... by Ong, Zongjue

“…This simulation is used to predict the deformation of the mold layer for nano-­‐imprint processes under variable conditions such as: 1) Different loading pressure 2) Different modulus of material 3) Different aspect ratio of structure 4) Bulging behavior with different materials For simulation to be accurate, mechanical properties of the materials are obtained by doing tensile tests on five dog-­‐bone samples of each material to acquire the engineering stress–strain curve. …”
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Glorious autarky? Foreign resources and the British fiscal-military state, 1688-1815 by Graham, A

“…Easy access to these resources enabled ministers to retain a bare-bones military and naval establishments in peacetime and then, in wartime, to ‘surge’ the state by using off- the-shelf foreign military labour to hold the line while British forces were recruited. …”

Mycoplasma iowae infection in young Turkeys by Bradbury, Janet M., Ideris, Aini, OO, Tin Tun

“…One group was infected orally at one day of age and some birds developed bone and joint abnormalities but another group, infected via both the thoracic air sac and the foot pad, also at one day of age, developed a higher incidence of these abnormalities, which included chondrodystrophy, rotated tibia, deviated toes and, in a few cases, erosion of the articular cartilage of the hock joint. …”
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Electrospun nanofibers of collagen and chitosan for tissue engineering and drug delivery applications: A review by Ramakrishnan, Praveen, Ramprasath, Ramakrishnan, Jalaludeen, Abdulkadhar Mohamed, R., Jayakumar, Gimbun, Jolius, Balu, Ranganathan, S.B., Mohamed, T.M., Sridhar, Gunasekaran, Sivagaami Sundari, Davoodbasha, MubarakAli, Thajuddin, Nooruddin, Gnanasekaran, Lalitha, Sundaram, Thanigaivel

“…Studies concerning the medical applications of these nanofibers, such as wound healing, skin regeneration, bone tissue engineering, and neural repair, were also reviewed. …”
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Microglia and CD206⁺ border-associated mouse macrophages maintain their embryonic origin during Alzheimer's disease by Wu, Xiaoting, Saito, Takashi, Saido, Takaomi C., Barron, Anna M., Ruedl, Christiane

“…We used a novel inducible AD mouse model to investigate the contribution of bone marrow (BM) cells to the pool of fetal-derived brain macrophages during the development of AD. …”
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Mechano-responsive hydrogel for direct stem cell manufacturing to therapy by Shou, Yufeng, Liu, Ling, Liu, Qimin, Le, Zhicheng, Lee, Khang Leng, Li, Hua, Li, Xianlei, Koh, Dion Zhanyun, Wang, Yuwen, Liu, Tong Ming, Yang, Zheng, Lim, Chwee Teck, Cheung, Christine, Tay, Andy

“…Bone marrow-derived mesenchymal stem cell (MSC) is one of the most actively studied cell types due to its regenerative potential and immunomodulatory properties. …”
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Capturing the fantastic voyage of monocytes through time and space by Teh, Ye Chean, Ding, Jeak Ling, Ng, Lai Guan, Chong, Shu Zhen

“…After birth, monocytes arise from bone marrow (BM)-derived HSCs and are released into the circulation upon their maturation, where they survey peripheral tissues and maintain endothelial integrity. …”
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Chemical analysis of silica doped hydroxyapatite biomaterials consolidated by a spark plasma sintering method by Xu, Jinling, Khor, Khiam Aik

“…HA was prepared with 0, 1, 3 and 5 wt% silica, which are comparable to the measured silicon content of natural bone. After spray drying into micron sized powders, the silica doped HA (SiHA) powders were consolidated at 1000 C with a dwell time of 3 min using a spark plasma sintering (SPS) technique. …”
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Investigating molecular vulnerabilities in TP53-mutant transformed myeloproliferative neoplasms by Paterson, A

“…To validate the selective requirement of PCBP2 in <em>TP53</em>-mutant LSC, I adopted a human bone marrow organoid model which I showed to outperform liquid culture conditions in supporting the survival and proliferation of <em>TP53</em>-sAML samples. …”

Kinematic analysis of an upper extremity stroke rehabilitation orthosis by Yang, Fang

“…This method also has some deficiencies, due to lack of the actual hand anatomy data for Singapore’s stroke patient, especially the joint angle of each finger bone, some assumptions and estimations are made. …”
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Development of bioactive PCL films using low temperature solvent free method by Lim, Lynette Sihui

“…In conclusion, based on the evaluation of the results, 10% MgCl2 has the potential to be developed as a bone scaffold.…”
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Molecular genetics of Dupuytren’s contracture by Aissvarya, Shankar, Ling, King-Hwa, Arumugam, Manohar, Thilakavathy, Karuppiah

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Mechanism of damnacanthal induced apoptosis in CEM-SS cell line by Gopalsamy, Banulata, Saiful Yazan, Latifah, Abdul Hamid, Hisyam

“…Leukaemia, is cancer of organs that is responsible to produce blood specifically the lymphatic system and bone marrow. Due to the harsh effects of currently used cancer drugs, damnacanthal, an anthraquinone obtained from the roots of Morinda elliptica is tested as a potential anticancer agent. …”
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Fracture energy and mechanical properties of toughened epoxy resin with eggshell powder by Fong, Collin, Sugiman, Sugiman, Chin, Desmond, Ahmad, Hilton

“…The material properties and fracture energy of toughened epoxy with eggshell powder (TEEP) were measured and investigated. Dog-bone specimens were fabricated to investigate the mechanical properties of TEEP (i.e. elastic modulus, Poisson’s ratios and tensile strength) and tested under quasi-static tensile loading. …”
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An implantable piezoelectric ultrasound stimulator (ImPULS) for deep brain activation by Hou, Jason F, Nayeem, Md Osman Goni, Caplan, Kian A, Ruesch, Evan A, Caban-Murillo, Albit, Criado-Hidalgo, Ernesto, Ornellas, Sarah B, Williams, Brandon, Pearce, Ayeilla A, Dagdeviren, Huseyin E, Surets, Michelle, White, John A, Shapiro, Mikhail G, Wang, Fan, Ramirez, Steve, Dagdeviren, Canan

“…Ultrasound can aid in energy propagation, but transcranial ultrasound stimulation in the deep brain has limited spatial resolution caused by bone and tissue scattering. Here, we report an implantable piezoelectric ultrasound stimulator (ImPULS) that generates an ultrasonic focal pressure of 100 kPa to modulate the activity of neurons. …”
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涂涂写写 = Alchemy of color and brushwork by Ng, Woon Lam

“…As brushwork strengthens the form, the three attributes of colors (namely tone, hue and chroma) are fine-tuned to either work with or against the results of the brushwork. …”
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The impact of the exercise on the social mentality of the Chinese people by Ji, Shuyu, Zhang, Kaiqi, Xu, Ludan, Wang, Xiaolin, Dong, Delong, Yang, Xiannan

“…It reflects an underlying emotional tone and cumulative value attributed to exercise by individuals, forming a broad, macro-level socio-psychological relationship in alignment with the conceptual definition of societal mentality. …”
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