The importance of understanding individual differences in Down syndrome by Karmiloff-Smith, Annette, Al-Janabi, Tamara, D'Souza, Hana, Groet, Jurgen, Massand, Esha, Mok, Kin, Startin, Carla, Fisher, Elizabeth, Hardy, John, Nizetic, Dean, Tybulewicz, Victor, Strydom, Andre

“…In this article, we first present a summary of the general assumptions about Down syndrome (DS) still to be found in the literature. …”
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Mitochondrial dysfunction in Down Syndrome: from pathology to therapy by Tan, Kai-Leng, Lee, Han-Chung, Cheah, Pike-See, Ling, King-Hwa

“…Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). …”
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Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome by Alford, KA, Slender, A, Vanes, L, Li, Z, Fisher, EMC, Nizetic, D, Orkin, SH, Roberts, I, Tybulewicz, VLJ

“…Trisomy of human chromosome 21 (Hsa21) results in Down syndrome (DS), a disorder that affects many aspects of physiology, including hematopoiesis. …”

The Things You Can See Only When You Slow Down / by Sunim, Haemin, author 655915

“…The Things You Can See Only When You Slow Down telah terjual lebih daripada tiga juta naskah di Korea Selatan dan menduduki tempat pertama dalam senarai buku terlaris selama 41 minggu berturut-turut.…”

Cross-Shelf Exchange Driven by Dense Flow Down a Canyon by Mier, Christian M.

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PLATON: top-down R-tree packing with learned partition policy by Yang, Jingyi, Cong, Gao

“…To address the limitations of existing R-tree packing methods, we propose PLATON, a top-down R-tree packing method with learned partition policy that explicitly optimizes the query performance with regard to the given data and workload instance. …”
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Global signal of top-down control of terrestrial plant communities by herbivores by Jia, Shihong, Wang, Xugao, Yuan, Zuoqiang, Lin, Fei, Ye, Ji, Hao, Zhanqing, Luskin, Matthew Scott

“…The theory of “top-down” ecological regulation predicts that herbivory suppresses plant abundance, biomass, and survival but increases diversity through the disproportionate consumption of dominant species, which inhibits competitive exclusion. …”
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Strange Things in Bottom-to-Strange Decays: The Standard Model Turned Upside Down? by Andersson, Martin, Marshall, Alexander Mclean, Petridis, Konstantinos A., Smith, Eluned

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Low-temperature specific heat capacity of water-ammonia mixtures down to the eutectic by Chua, Bing Hong, Gloesener, Elodie, Choukroun, Mathieu, Vu, Tuan H., Melwani Daswani, Mohit, Journaux, Baptiste, Styczinski, Marshall J., Vance, Steven D.

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Small towing tank for accurate testing of significantly scaled-down ship models by Chung, Hau Kim.

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Why shoot it down now? : understanding China's missile firing into outer space by Horta, Loro

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Understanding perspectives and research trends in down syndrome neuropathogenesis: a bibliometric analysis by Huang, Tan, Lam, Xin-Jieh, Lim, Chong-Teik, Jusoh, Norhazlin, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa

“…Down syndrome (DS), characterised by compromised brain development and intellectual challenges, often manifests Alzheimer's disease (AD) -like symptoms. …”
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Nanosphere lithography for ordered-arrayed semiconductor nanowire formation via top-down method by Low, Guorong.

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Knocking down MEG3 long non-coding RNA to Counteract Necroptosis in vitro by Kemp, E

Development of a cellulose-based 96-well plate vertical flow pull-down assay by Cheng, Hoi Lok, Jia, Huan, Lim, Sing Mei, Ng, Say Yong, Kongsuphol, Patthara, McBee, Megan E., Sikes, Hadley D.

“…Here, we present the development of a high-throughput cellulose-based 96-well plate vertical flow pull-down assay that can process 96 tests, is easy to prepare, and can be customized for different detection targets. …”
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REST targets JAK–STAT and HIF-1 signaling pathways in human Down syndrome brain and neural cells by Huang, Tan, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa

“…Down syndrome (DS) is the most frequently diagnosed chromosomal disorder of chromosome 21 (HSA21) aneuploidy, characterized by intellectual disability and reduced lifespan. …”
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Variable-Inverter-Rectifier-Transformer: A Hybrid Electronic and Magnetic Structure Enabling Adjustable High Step-Down Conversion Ratios by Moon, Intae, Ranjram, Mike Kavian, Perreault, David J

“…This functionality is valuable in converters with wide operating voltage ranges and high step-up/down, as it offers a means to reduce copper loss within the transformer while also facilitating voltage doubling and quadrupling. …”
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Forecasting item-level demands : an analytical evaluation of top-down versus bottom-up forecasting in a production-planning framework by Viswanathan, S., Widiarta, Handik, Piplani, Rajesh

“…We compare the performance of top–down (TD) and bottom–up (BU) strategies for forecasting the demand of an item that belongs to a product family. …”
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Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing by Rujitanaroj, Pim-On, Jao, Brian, Yang, Junghoon, Wang, Feng, Anderson, James M., Wang, Jun, Chew, Sing Yian

“…In this study, we investigated the efficacy of siRNA–poly(caprolactone-co-ethylethylene phosphate) nanofibers in controlling fibrous capsule formation through the down-regulation of collagen type I (COL1A1) in vitro and in vivo. …”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

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