Enhancing the photo-electrocatalytic properties of g-C3N4 by boron doping and ZIF-8 hybridization by Atta, Mahmood Riyadh, Maizatul Shima, Shaharun, Khan, Maksudur Rahman Md, Bawadi, Abdullah, Al-Mahmodi, Akram Fadhl, Nur Diyan, Mohd Ridzuan, Munusamy, Thurga Devi, Jun Wei, Lim

“…As a result, merging these modifications noticeably enhanced the photo-electrocatalytic activity and light sensitivity of the main catalyst, which opens a wider range of applications and future research.…”
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Cryogelation of human hair keratins by Chua, Huei Min

“…Nonetheless, conventional methods to translate HHK proteins into meaningful three-dimensional (3D) constructs often require chemical modifications or cross-linking additives. Such processing routes can be complicated and may compromise the resultant biocompatibility of the scaffolds. …”
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Information retrieval and multimodal sentiment analysis for climate change by Duong, Cuc Thi Kim

“…The Intergovernmental Panel on Climate Change (IPCC) has affirmed that human activities persist in elevating the global mean temperature, altering extreme weather patterns like heatwaves, droughts, tropical cyclones, and heavy rainfall. These climatic modifications pose significant economic and social threats if not promptly and effectively addressed. …”
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MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors by Kim, HaEun, Lebeau, Benjamin, Papadopoli, David, Jovanovic, Predrag, Russo, Mariana, Avizonis, Daina, Morita, Masahiro, Afzali, Farzaneh, Ursini-Siegel, Josie, Postovit, Lynne-Marie, Witcher, Michael, Topisirovic, Ivan

“…However, the relationship between the mechanistic target of rapamycin (mTOR), which is a pivotal metabolic regulator, and epigenetic modifications remains poorly understood. Our results show that mTORC1 activation caused by the abrogation of its negative regulator tuberous sclerosis complex 2 (TSC2) coincides with increased levels of the histone modification H3K27me3 but not H3K4me3 or H3K9me3. …”
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Layer-by-layer assembled micro and nano carriers for drug delivery applications by Mutukumaraswamy Shaillender

“…To summarize, this thesis illustrates the modifications of the LbL concept in different applications such as protein delivery, gene delivery, controlled release, and passive targeting. …”
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Structural and functional studies of C-nucleoside formation enzymes by Li, W

“…In the 20th century, industrialisation and scientific knowledge saw a boom in active single compounds isolated from nature and used to treat disease directly or after relatively minor chemical modification. However, by the end of the 20th century this approach had fallen out from favour. …”

The influence of pregnancy complications on fetal and neonatal cardiovascular development by Aye, C

“…Higher blood pressure has also been observed in those born preterm in addition to specific cardiac modifications in young adulthood.</p> <p>Through detailed cardiovascular phenotyping, this thesis investigates the effects of exposure to <em>in utero</em> maternal hypertension and/or a preterm birth on offspring cardiovascular development in the antenatal and early postnatal period in a newly established cohort of infants. …”

Online estimation of key battery states for management of vanadium redox flow battery by Wei, Zhongbao

“…The proposed peak power estimator is verified with a “two-step verification” method. The influence of prediction time horizon on the peak power is also analyzed. …”
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Conformational design characterization of a truncated diamine oxidase by Razali, Nur Nadia

“…Quality assessments of the native and mini protein were also conducted using several types of verification software. Subsequently, a number of model structures were generated using a biomolecular method where the native and mini protein has been successfully cloned into vector pET102/TOPO during the first stage. …”
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Evaluation of keratin templates on dermal regeneration of full-thickness burns by Moay, Zi Kuang

“…All in all, HHK foams are capable as dermal substitutes to treat full-thickness burn wounds through promoting earlier angiogenesis in the surrounding tissue, though it would require further modifications to improve its potential of being an ideal dermal substitute.…”
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Development of high-affinity peptide-drug conjugates for investigating the TRIM24 PHD and bromodomain by Platt, MA

“…<p>Tripartite motif-containing protein 24 (TRIM24) is an epigenetic transcriptional regulator involved in reading histone 3 (H3) methylated (KMe_<em>x</em>) and acetylated (KAc) lysine post-translational modifications (PTMs) through an adjacent plant homeodomain-bromodomain (PHD-BRD) cassette, respectively. …”

Advanced data analytics for future smart grid stability assessment by Ren, Chao

“…Fourthly, in order to accurately quantify the robustness of the ML-based model under adversarial perturbations on safety-critical power system stability problem, an adversarial robustness verification method for data-driven stability models is proposed. …”
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Part I Targeting RNA duplexes with modified triplex-forming oligonucleotides Part II Allostery within a Watson-Crick RNA duplex and its application in studying RNA recognition by R... by Zhou, Yuan

“…UV-absorbance-detected thermal melting studies reveal that the LNA and 2-thio U modifications in TFOs strongly enhance triplex formation with both parental RNA and DNA duplex regions. …”
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Studies of insulin transport across intestinal epithelium using nano-encapsulation for oral delivery by Zhang, Yiming

“…The studies of insulin transport across intestinal epithelial cells were investigated from three general areas; interaction of empty liposomes with intestinal epithelial Caco-2 cells, cellular interaction and transport of insulin loaded liposomes with appropriated surface modifications across Caco-2 cells, loading of insulin onto surface of liposomes for enhanced transport, improved loading, and sustained release. …”
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Space charge induced beam loss on a high intensity proton synchrotron by Pine, B

“…One such feature is the conformal rectangular vacuum vessel, which takes the shape of the design beam envelope with certain modifications. This vacuum vessel has a complex effect on beam image fields.…”

Physical unclonable function based solutions to unification of user, device and data authentication by Zheng, Yue

“…At a time of rampant public media manipulation and ease of fake image/video fabrication, verification of benign and malicious image transformations is necessary but not sufficient for fact checking of visual artefacts presented in the court of law. …”
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Clustering-based solutions for energy efficiency, adaptability and resilience in IoT networks by Shivaraman, Nitin

“…E.g. fault-resilient solutions use complex computations for verification of devices and data that inadvertently reduce the energy efficiency in a resource-constrained environment. …”
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Priorities to inform research on marine plastic pollution in Southeast Asia by Omeyer, Lucy C. M., Duncan, Emily M., Aiemsomboon, Kornrawee, Beaumont, Nicola, Bureekul, Sujaree, Cao, Bin, Carrasco, Luis R., Chavanich, Suchana, Clark, James R., Cordova, Muhammad R., Couceiro, Fay, Cragg, Simon M., Dickson, Neil, Failler, Pierre, Ferraro, Gianluca, Fletcher, Stephen, Fong, Jenny, Ford, Alex T., Gutierrez, Tony, Shahul Hamid, Fauziah, Hiddink, Jan G., Hoa, Pham T., Holland, Sophie I., Jones, Lowenna, Jones, Nia H., Koldewey, Heather, Lauro, Federico M., Lee, Charlotte, Lewis, Matt, Marks, Danny, Matallana-Surget, Sabine, Mayorga-Adame, Claudia G., McGeehan, John, Messer, Lauren F., Michie, Laura, Miller, Michelle A., Mohamad, Zeeda F., Nor, Nur Hazimah Mohamed, Müller, Moritz, Neill, Simon P., Nelms, Sarah E., Onda, Deo Florence L., Ong, Joyce J. L., Pariatamby, Agamuthu, Phang, Sui C., Quilliam, Richard, Robins, Peter E., Salta, Maria, Sartimbul, Aida, Shakuto, Shiori, Skov, Martin W., Taboada, Evelyn B., Todd, Peter A., Toh, Tai Chong, Valiyaveettil, Suresh, Viyakarn, Voranop, Wonnapinij, Passorn, Wood, Louisa E., Yong, Clara L. X., Godley, Brendan J.

“…Using an inductive method, 21 research questions emerged under five non-predefined key themes, grouping them according to which: (1) characterise marine plastic pollution in Southeast Asia; (2) explore its movement and fate across the region; (3) describe the biological and chemical modifications marine plastic pollution undergoes; (4) detail its environmental, social, and economic impacts; and, finally, (5) target regional policies and possible solutions. …”
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AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

“…We show that the molecules selected by the AtomNet® model are novel drug-like scaffolds rather than minor modifications to known bioactive compounds. Our empirical results suggest that computational methods can substantially replace HTS as the first step of small-molecule drug discovery.…”
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Strategies to modulate Amorphous Oxide Semiconductor properties for low temperature transparent transistors by Kulkarni, Mohit Rameshchandra

“…Another method for selective on-demand modification of TFT properties using chemical surface treatment was also explored in the dissertation. …”
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