Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction by Wood, GK, Sargent, BF, Ahmad, Z, Tharmaratnam, K, Dunai, C, Egbe, FN, Martin, NH, Facer, B, Pendered, SL, Rogers, HC, Hübel, C, van Wamelen, DJ, Bethlehem, RAI, Giunchiglia, V, Hellyer, PJ, Trender, W, Kalsi, G, Needham, E, Easton, A, Jackson, TA, Cunningham, C, Upthegrove, R, Pollak, TA, Hotopf, M, Miller, KL, Jezzard, P, Smith, SM, Husain, M, Vincent, A

“…The spectrum, pathophysiology and recovery trajectory of persistent post-COVID-19 cognitive deficits are unknown, limiting our ability to develop prevention and treatment strategies. …”

Remote digital cognitive assessment reveals cognitive deficits related to hippocampal atrophy in autoimmune limbic encephalitis: a cross-sectional validation study by Shibata, K, Attaallah, B, Tai, X-Y, Trender, W, Hellyer, PJ, Hampshire, A, Irani, SR, Manohar, SG, Husain, M

“…<p><strong>Background:</strong> Autoimmune limbic encephalitis (ALE) is a neurological disease characterised by inflammation of the limbic regions of the brain, mediated by pathogenic autoantibodies. Because cognitive deficits persist following acute treatment of ALE, the accurate assessment of long-term cognitive outcomes is important for clinical assessments and trials. …”

Gradient bandgap-tunable perovskite microwire arrays toward flexible color-cognitive devices by Fu, Yue, Yuan, Meng, Zhao, Yingjie, Dong, Meiqiu, Guo, Yangwu, Wang, Kui, Jin, Chunqi, Feng, Jiangang, Wu, Yuchen, Jiang, Lei

“…Furthermore, the integrated flexible color-cognitive devices are demonstrated for accurately recognizing similar colors, which can be applied in color blindness correction. …”
Get full text

Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol by Svensson, Jonas E., Bolin, Martin, Thor, Daniel, Williams, Pete A., Brautaset, Rune, Carlsson, Marcus, Sörensson, Peder, Marlevi, David, Spin-Neto, Rubens, Probst, Monika, Hagman, Göran, Morén, Anton Forsberg, Kivipelto, Miia, Plavén-Sigray, Pontus

“…Results from mouse models of Alzheimer’s disease have shown beneficial effects of rapamycin, including preventing or reversing cognitive deficits, reducing amyloid oligomers and tauopathies and normalizing synaptic plasticity and cerebral glucose uptake. …”
Get full text

Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y., Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah-Leong, Arumugam, Thiruma V.

“…Conclusions: These findings provide an understanding of how IF may protect the brain against damage caused by CCH and show promise in offering potential beneficial effects in mitigating the neuropathology and cognitive deficits in VaD.…”
Get full text

Study on the implementation intention of health protection behavior of college students in epidemic situation of infectious diseases by Ye, He, Mahamed, Mastura, Sha'ri, Sharil Nizam

“…The existence of cognitive deficit and optimism bias results in the failure of the predictive power of the element of threat assessment on the willingness to carry out health behaviors, however, perceived severity can have a negative effect on health behavior intention through the mediation of the “Avoidance” concept. …”
Get full text