RNA interference silencing of interleukin-6 in mesenchymal stromal cells and antitumour efficacy against multiple myeloma cells by Teoh, Hoon Koon

“…Studies demonstrated that mesenchymal stromal cells (MSC) from bone marrow (BM) stroma produced high concentrations of interleukin-6 (IL-6) that promoted multiple myeloma growth. …”
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Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity by Syed Moiz Ahmed

“…I attribute this wide-spread protection across various cell lines tested in this study to the constrainment of sc DNA and/or catalytic activation of TOP2A mediated by HMGA2, which, remarkably, could provide a mechanistic explanation for the recent observation of poor clinical outcomes in bone-marrow derived mononuclear cells of acute myeloid leukemia patients that express HMGA2. …”
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3D content recovery and complexity reduction by Tan, Cheen Hau

“…To alleviate this problem, we exploit the fact that human bones are rigid and constrain inter-joint distances of connected joints. …”
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Self-learning shape recognition in medical images by Ma, Jingting

“…Experiments are conducted using two representative datasets, a set of 30 public CT kidneys and a set of 49 internal MRI ankle bones. Embedded into an existing segmentation framework, experimental results show that SSM built with the proposed RKPCA outperforms the state-of-the-art modeling techniques in terms of model quality and segmentation accuracy. …”
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