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"kidney transplantation" » "liver transplantation" (Expand Search)
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"_ translocation" » "_ translation" (Expand Search), "_ transformation" (Expand Search), "_ transportation" (Expand Search)
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Predicting graft and patient outcomes following kidney transplantation using interpretable machine learning models
Published 2024“…This project uses interpretable methods to predict both graft failure and patient death using data from previously accepted kidney transplant offers. Using more than 25 years of transplant outcome data, we train and compare several survival analysis models in single risk settings. …”
Journal article -
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Injectable cell transplantation system for cytokine-based cancer immunotherapy
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Final Year Project (FYP) -
3
Therapeutic and immunomodulatory functions of the translocator protein in Alzheimer's disease
Published 2022“…Alzheimer’s disease (AD) is an age-associated neurodegenerative disease with no effective treatments. The translocator protein (TSPO) has been identified as a promising therapeutic target in AD, as TSPO ligands reduce the accumulation of beta-amyloid. …”
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Thesis-Doctor of Philosophy -
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Direct quantification of the translocation activities of Saccharomyces cerevisiae Pif1 helicase
Published 2020“…Besides its DNA helicase activity, ScPif1 is also known as a single-stranded DNA (ssDNA) translocase, while how ScPif1 translocates on ssDNA is unclear. Here, by measuring the translocation activity of individual ScPif1 molecules on ssDNA extended by mechanical force, we identified two distinct types of ssDNA translocation. …”
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Journal Article -
6
Identifying candidate proteins that undergo activity-dependent synapse to nucleus translocation in hippocampal neurons
Published 2017“…We also look for possible nuclear translocation in the form of nuclear localising protein motifs in their sequences. …”
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Final Year Project (FYP) -
7
Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons
Published 2015“…CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to regulate the transcription of CREB target genes. …”
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Journal Article -
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The history of Koi aquaculture in Singapore from 1965 to the present : translating translocated scientific knowledge from Japan into biosecurity
Published 2018“…In this thesis, I analysed the translocation of Japanese koi to Singapore from 1965 to 2018. …”
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Thesis -
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Structural study of ribosome : 1) structural basis of EF-G in translocation. 2) molecular mechanism of ribosome-dependent toxin YoeB in mRNA cleavage
Published 2015“…This process, known as translocation, is the most conserved part between prokaryotic and eukaryotic translation. …”
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Thesis -
10
Partially Oxidized Alginate as a Biodegradable Carrier for Glucose‐Responsive Insulin Delivery and Islet Cell Replacement Therapy
Published 2024“…Two approaches towards this goal are glucose‐responsive insulin delivery and islet cell transplantation therapy. Here, biodegradable, partially oxidized alginate carriers for glucose‐responsive nanoparticles or islet cells are developed. …”
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Global availability of medications and health technologies for kidney care: A multinational study from the ISN-GKHA
Published 2025“…Public funding (and free at point of delivery) for medications for dialysis and kidney transplantation was available in only 24% (n = 39) and 30% (n = 50) of countries worldwide, with the proportion increasing in line with country income levels. …”
Journal article -
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Material augmented plant development
Published 2021“…In addition, translocation after foliar application has never been studied. …”
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Final Year Project (FYP) -
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Injectable transplantation system for anticancer in-situ cell therapy
Published 2009“…In this project, we are aiming to evaluate the feasibility of remodeling immunosurveillance into the tumor site, with an engineering, more particularly, functional materials-mediated cell therapeutic strategy by designing an injectable cell transplantation system for anti-cancer therapy. The RAW 264.7 cells are encapsulated in dual-layer hydrogel composite which is in injectable size. …”
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Final Year Project (FYP) -
14
Ex vivo expansion and genetic manipulation of mouse hematopoietic stem cells in polyvinyl alcohol-based cultures
Published 2023“…HSCs are used clinically in stem cell transplantation therapies, which represent curative treatment for a range of blood diseases. …”
Journal article -
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A qualitative systematic review of anonymous/unspecified living kidney and liver donors' perspectives
Published 2023“…Methods: A systematic search was conducted on Medline, Embase, CINAHL, PsycINFO, and Web of Science database for qualitative literature regarding unspecified living donors’ motivations and experiences in liver and kidney transplantation. An inductive thematic analysis was conducted to generate themes and supportive subthemes. …”
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Journal Article -
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Root uptake and phytotoxicity of zinc oxide nanoparticles on the scirpus validus
Published 2013“…Validus to significantly uptake ENPs in the roots, and highlights the poor translocation of the ENPs from roots to shoots of the S. …”
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Final Year Project (FYP) -
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Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain
Published 2018“…However, unlike CRTC1, we provide evidence that CRTC2 in neurons do not undergo activity-dependent nuclear translocation. Chemical stimulation of acute brain slices to promote long-term potentiation (LTP) also did not trigger CRTC2 nuclear accumulation in hippocampal excitatory neurons. …”
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Thesis-Doctor of Philosophy -
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Afterword: ten pound poms
Published 2024“…By comparing the books to other, human migrants, those 'ten pound poms' who travelled from the UK to Australia contemporaneously with Emmerson's collecting, themes of belonging, migration and translocation are explored. Charles I's travelling library, the one object that Emmerson separated from his collection and donated to a UK institution, comes to symbolise these bibliographic energies.…”
Journal article -
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Materials approaches for next-generation encapsulated cell therapies
Published 2024“…However, attack from the host immune system represents a major challenge, requiring chronic immunosuppression to enable long-lived cell transplantation in vivo. Encapsulating cells in engineered biomaterials capable of excluding components of the host immune system while allowing for the transport of therapeutic proteins, oxygen, nutrients, metabolites, and waste products represents a potential solution. …”
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The role of transportin-1 in the ciliary targeting of membrane proteins
Published 2016“…We found that non-ciliary membrane reporters could passively diffuse to cilia via the lateral transport pathway and the translocation of membrane reporters through ciliary diffusion barrier could be facilitated by importin binding motifs/domains. …”
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Thesis