Predicting graft and patient outcomes following kidney transplantation using interpretable machine learning models by Salaun, A, Knight, S, Wingfield, L, Zhu, T

“…Clinical decision support tools predicting transplant outcomes are lacking. This project uses interpretable methods to predict both graft failure and patient death using data from previously accepted kidney transplant offers. …”

Uterus transplants and Mexico’s rule of law by Palacios-González, C, Mendoza Cárdenas, HA

“…Uterus transplantation is a new fertility treatment for some women who lack a functioning uterus. …”

Injectable transplantation system for anticancer in-situ cell therapy by Sheng, Nan.

“…In this project, we are aiming to evaluate the feasibility of remodeling immunosurveillance into the tumor site, with an engineering, more particularly, functional materials-mediated cell therapeutic strategy by designing an injectable cell transplantation system for anti-cancer therapy. The RAW 264.7 cells are encapsulated in dual-layer hydrogel composite which is in injectable size. …”
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Robotic inspection and repair of gas and fluid transplant structures by Low, Eicher., Nickols, Francis Malcolm John.

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Injectable cell transplantation system for cytokine-based cancer immunotherapy by Gerard Nathanael Adrianus.

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Differential response of the microbiome of pocillopora acuta to reciprocal transplantation within singapore by Deignan, Lindsey Kane, McDougald, Diane

“…Amplicon sequencing (16S rRNA) was used to assess the coral microbiomes at 1, 2, 4, and 10 days post-transplantation. Coral microbiomes responded rapidly to transplantation, becoming similar to those of the local corals at the destination reef within one day at Raffles and within two days at Kusu. …”
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Translational assessment of a genetic engineering methodology to improve islet function for transplantation by van Krieken, Pim P., Voznesenskaya, Anna, Dicker, Andrea, Xiong, Yan, Park, Jae Hong, Lee, Jeong Ik, Ilegems, Erwin, Berggren, Per-Olof

“…Background: The functional quality of insulin-secreting islet beta cells is a major factor determining the outcome of clinical transplantations for diabetes. It is therefore of importance to develop methodological strategies aiming at optimizing islet cell function prior to transplantation. …”
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Understanding liver transplantation outcomes through the lens of its tissue-resident immunobiome by Prosser, AC, Klenerman, P, Lucas, M

“…The importance of donor- and recipient-derived TRLs after transplantation is becoming increasingly recognized, although it has not been examined in detail after liver transplantation. …”

Investigation of CD27-CD70 co-stimulation in human regulatory T cells for enhanced cellular therapy in transplantation by Arroyo Hornero, RC

“…<p>CD4+FOXP3+ regulatory T cells (Tregs) are essential for maintaining immune homeostasis and are a focus of investigation in the treatment of transplant rejection and autoimmune diseases. Current clinical protocols for Treg cellular therapy production are heavily reliant on in vitro expansion techniques. …”

Naïve B cells followed by aquaporin-4 antibodies characterise the onset of neuromyelitis optica: evidence from stem cell transplantation by McNaughton, P, Payne, R, Michael, S, Leahy, T, Nicols, A, Fower, A, Hambleton, S, Pang, K, Gennery, A, Irani, SR

21A.216J / SP.622J / WGS.622J Dilemmas in Bio-Medical Ethics: Playing God or Doing Good?, Spring 2005 by James, Erica

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Clinical course, immunogenicity, and efficacy of BNT162b2 mRNA vaccination against SARS-CoV-2 infection in liver transplant recipients by Tan, Eunice X., Lim, Wen Hui, Thong, Elizabeth, Chavatte, Jean-Marc, Zhang, Jinyan, Lim, Jonathan, Jin, Jocelyn Y., Lim, Daniel R. X., Kang, Jaclyn Y. T., Tang, Ansel Shao Pin, Chan, Kai En, Tan, Caitlyn, Tan, Shi Ni, Nah, Benjamin, Huang, Daniel Q., Wang, Lin-Fa, Tambyah, Paul A., Somani, Jyoti, Young, Barnaby Edward, Muthiah, Mark D.

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Antigen–antibody complex density and antibody-induced HLA protein unfolding influence Fc-mediated antibody effector function by Murali, TM, Gu, Y, Minhat, RA, Yap, J, Wood, KJ, Wang, C, Gascoigne, NRJ, Anantharaman, V, MacAry, PA

“…Donor-specific antibodies (DSAs) targeting mismatched human leukocyte antigen (HLA) molecules are one of the principal threats to long-term graft survival in solid organ transplantation. However, many patients with long-term circulating DSAs do not manifest rejection responses, suggesting a degree of heterogeneity in their pathogenicity and related functional activity. …”

Wearable bioadhesive ultrasound shear wave elastography by Liu, Hsiao-Chuan, Zeng, Yushun, Gong, Chen, Chen, Xiaoyu, Kijanka, Piotr, Zhang, Junhang, Genyk, Yuri, Tchelepi, Hisham, Wang, Chonghe, Zhou, Qifa, Zhao, Xuanhe

“…BAUS-E holds promise for clinical applications, particularly in patients after organ transplantation or postoperative care in the intensive care unit (ICU).…”
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Telomere biology disorders by Kam, Michelle L. W., Nguyen, Trang T. T., Ngeow, Joanne Yuen Yie

“…There is no specific cure and the only treatment is organ transplantation, which has poor outcomes. This review summarises the current literature and discusses gaps in understanding and areas of need in managing TBD.…”
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Global availability of medications and health technologies for kidney care: A multinational study from the ISN-GKHA by Kelly, DM, Jones, ESW, Barday, Z, Arruebo, S, Caskey, FJ, Damster, S, Donner, J, Jha, V, Levin, A, Nangaku, M, Saad, S, Tonelli, M, Ye, F, Okpechi, IG, Bello, AK, Johnson, DW

“…Public funding (and free at point of delivery) for medications for dialysis and kidney transplantation was available in only 24% (n = 39) and 30% (n = 50) of countries worldwide, with the proportion increasing in line with country income levels. …”

A qualitative systematic review of anonymous/unspecified living kidney and liver donors' perspectives by Lim, Wen Hui, Chan, Kai En, Ng, Cheng Han, Tan, Darren Jun Hao, Tay, Phoebe Wen Lin, Chin, Yip Han, Yong, Jie Ning, Xiao, Jieling, Fu, Clarissa Elysia, Nah, Benjamin, Tiong, Ho Yee, Syn, Nicholas, Devi, Kamala, Griva, Konstadina, Mak, Loey Lung Yi, Huang, Daniel Q., Fung, James, Siddiqui, Mohammad Shadab, Muthiah, Mark, Tan, Eunice X. X.

“…Methods: A systematic search was conducted on Medline, Embase, CINAHL, PsycINFO, and Web of Science database for qualitative literature regarding unspecified living donors’ motivations and experiences in liver and kidney transplantation. An inductive thematic analysis was conducted to generate themes and supportive subthemes. …”
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Ex vivo expansion and genetic manipulation of mouse hematopoietic stem cells in polyvinyl alcohol-based cultures by Khoo, HM, Meaker, GA, Wilkinson, AC

“…Self-renewing multipotent hematopoietic stem cells (HSCs) are an important cell type due to their abilities to support hematopoiesis throughout life and reconstitute the entire blood system following transplantation. HSCs are used clinically in stem cell transplantation therapies, which represent curative treatment for a range of blood diseases. …”

Long term survival of human skeletal myoblast cells in a porcine heart model of chronic ischemia by Jiang, Shujia

“…Our project is intended to ascertain the feasibility, usefulness and survival of human skeletal myoblast (HSM) as donor cells for transplantation into damaged myocardium for cardiac repair. …”
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Partially Oxidized Alginate as a Biodegradable Carrier for Glucose‐Responsive Insulin Delivery and Islet Cell Replacement Therapy by Volpatti, Lisa R, Bochenek, Matthew A, Facklam, Amanda L, Burns, Delaney M, MacIsaac, Corina, Morgart, Alexander, Walters, Benjamin, Langer, Robert, Anderson, Daniel G

“…Two approaches towards this goal are glucose‐responsive insulin delivery and islet cell transplantation therapy. Here, biodegradable, partially oxidized alginate carriers for glucose‐responsive nanoparticles or islet cells are developed. …”
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