Visual Acuity Outcomes and Influencing Factors in a Cohort of UK Real-World Diabetic Macular Oedema Patients During the First Two Years of Anti-VEGF Treatment by Wen, Qing, Karcher, Helene, Wright, David M., Sinha, Samriddhi Buxy, Chakravarthy, Usha, Santos, Catarina, Igwe, Franklin, Salongcay, Recivall, Curran, Katie, Peto, Tunde

“…In the first year, the median annual injection number and interval were 6.0 (IQR 5.0–8.0) and 6.1 weeks (IQR 5.4–7.8), respectively, and in the second year, they were 3.0 (IQR 2.0–5.0) and 10.0 weeks (IQR 6.5–20.1). …”
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Classifying vulnerability to sleep deprivation using baseline measures of psychomotor vigilance by Kwoh, Chee Keong, Gooley, Joshua J., Patanaik, Amiya, Chua, Eric C. P., Chee, Michael W. L.

“…Participants were categorized as vulnerable or resistant to sleep deprivation, based on a median split of lapses that occurred following sleep deprivation. …”
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Exposure to Pb-halide perovskite nanoparticles can deliver bioavailable Pb but does not alter endogenous gut microbiota in zebrafish by Patsiou, Danae, del Rio-Cubilledo, Cristina, Catarino, Ana Isabel, Summers, Stephen, Afiq Mohd Fahmi, Boyle, David, Fernandes, Teresa F., Henry, Theodore B.

“…Zebrafish larvae were exposed to five Pb-halide perovskite NPs in parallel with Pb(NO3)2 exposures, and zebrafish adults were exposed to the three perovskite NPs that caused the strongest effect and Pb(NO3)2. No median lethal concentration (LC50) was observed for zebrafish larvae exposed to up to 200 mg/L of perovskite NPs for 96 h. …”
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Infectious diseases acquired by international travellers visiting the USA by Stoney, Rhett J, Esposito, Douglas H., Kozarsky, Phyllis, Hamer, Davidson H., Grobusch, Martin P., Gkrania-Klotsas, Effrossyni, Libman, Michael, Gautret, Philippe, Lim, Poh Lian, Leder, Karin, Schwartz, Eli, Sotir, Mark J., Licitra, Carmelo

“…Results: There were 1222 ill non-US-resident travellers with 1393 diagnoses recorded during the 20-year analysis period. Median age was 40 (range 0–86 years); 52% were female. …”
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Real-world effectiveness of sotrovimab and remdesivir for early treatment of high-risk hospitalized COVID-19 patients: a propensity score adjusted retrospective cohort study by Koh, Lin Pin, Chua, Siang Li, Vasoo, Shawn, Toh, Matthias Paul Han Sim, Cutter, Jeremy Nicholas, Nah, Puay Hoon, Leo, Yee Sin, Tay, Jun Xin, Young, Barnaby Edward, Lye, David C., Ong, Sean W. X.

“…Of 1118 patients, 841 were in the control group, 106 in the sotrovimab group and 169 in the remdesivir group. The median age was 63 years (IQR 46-74 years) and 505 (45.2%) were female. …”
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Lipid-mediated resolution of inflammation and survival in amyotrophic lateral sclerosis by Yildiz, O, Hunt, GP, Schroth, J, Dhillon, G, Spargo, TP, Al-Chalabi, A, Koks, S, Turner, MR, Shaw, PJ, Henson, SM, Iacoangeli, A, Malaspina, A

“…Higher GPR32 and GPR18 median expression in blood mononuclear cells was associated with longer survival, with GPR32 expression in classical monocytes (hazard ratio: 0.11, P = 0.003) and unswitched memory B cells (hazard ratio: 0.44, P = 0.008) showing the most significant association, along with known clinical predictors. …”

Diagnostic performance of GENEDIA W and ActiveXpress+ COVID-19 antigens tests among symptomatic individuals in Peru and The United Kingdom by Palomino-Padilla, S, Finch, L, de Vos, M, Savage, H, Villa-Castillo, L, Hayward, G, Cook, E, LSTM diagnostics group, UTB-IMTAvH group, CONDOR steering group, Escadafal, C, Body, R, Adams, ER, Ugarte-Gil, C, Cubas-Atienzar, AI

“…The UK cohort had lower median Ct values compared to that of Peru during both evaluations. …”

Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors for new-onset gastric cancer and gastric diseases in patients with type 2 diabetes mellitus: a population-bas... by Chou, OHI, Chauhan, VK, Chung, CTS, Lu, L, Lee, TTL, Ng, ZMW, Wang, KKW, Lee, S, Liu, H, Pang, RTK, Kaewdech, A, Cheung, BMY, Tse, G, Zhou, J

“…</p> <p><strong>Results: </strong>A total of 62,858 patients (median age: 62.2&nbsp;years old [SD: 12.8]; 55.93% males; SGLT2I: n&thinsp;=&thinsp;23,442; DPP4I: n&thinsp;=&thinsp;39,416) were included. …”

Efficacy of five insecticides against bagworm, Metisa plana Walker and their side effects on oil palm pollinator, Elaeidobius kamerunicus Faust by Syed Mohamed, Syed Mazuan

“…Stihl SR420 mistblower was characterised by having 1.2L / min flow rate, produced volume median diameter of 80μm, and achieved productivity of approximately of 2.58 hectares per man day. …”
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Correlative light and electron microscopy of telomeric repeat-binding factor 1 in mammalian cells by von Otter, Eric

“…EM analysis of cell sections shows that telomeres have a median diameter of 156 nm and 196 nm in HT1080 and MEFs, respectively. …”
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Cytogenetic and molecular aberrations of multiple myeloma patients : a single-center study in Singapore by Ng, Yit Jun, Tan, Yu Min, See, Karen Hsu Shien, Choo, Natasha Swee Lian, Lim, Sherry Xin Er, Lim, Alvin Soon Tiong, Lim, Tse Hui, Yee, Yenny, Lau, Lai Ching, Tien, Sim Leng, Sathish, Kumar, Tan, Daryl Chen Lung

“…Methods-Forty-five newly-diagnosed, morphologically confirmed patients comprising 18 males and 27 females, aged 46-84 years (median 65 years) were investigated by karyotyping and fluorescence in situ hybridization (FISH). …”
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Long Covid: a global health issue – a prospective, cohort study set in four continents by Pazukhina, E, Garcia-Gallo, E, Reyes, LF, Kildal, AB, Jassat, W, Dryden, M, Holter, JC, Chatterjee, A, Gomez, K, Søraas, A, Puntoni, M, Latronico, N, Bozza, FA, Edelstein, M, Gonçalves, BP, Kartsonaki, C, Kruglova, O, Gaião, S, Chow, YP, Doshi, Y, Duque Vallejo, SI, Ibáñez-Prada, ED, Fuentes, YV, Hastie, C, O'Hara, ME, Balan, V, Menkir, T, Merson, L, Kelly, S, Citarella, BW, Semple, MG, Scott, JT, Munblit, D, Sigfrid, L

“…<p><strong> Results </p></strong>Of 11 860 participants (median age: 52 (IQR: 41–62) years; 52.1% females), 56.5% were from HICs and 43.5% were from LMICs. …”

Cardiovascular risk factors in childhood and adulthood and cardiovascular disease in Middle Age by Kartiosuo, N, Raitakari, OT, Juonala, M, Viikari, JSA, Sinaiko, AR, Venn, AJ, Jacobs, DR, Urbina, EM, Woo, JG, Steinberger, J, Bazzano, LA, Daniels, SR, Magnussen, CG, Rahimi, K, Dwyer, T

“…The mean (SD) age at CVD event or censoring was 49.2 (7.0) years. The median (IQR) follow-up time was 23.6 (18.7-30.2) years. …”

Risk prediction models to guide antibiotic prescribing : a study on adult patients with uncomplicated upper respiratory tract infections in an emergency department by Wong, Joshua Guoxian, Aung, Aung-Hein, Lian, Weixiang, Lye, David Chien, Ooi, Chee-Kheong, Chow, Angela

“…Decision trees, LASSO and logistic regression models were built to predict when antibiotics were not needed. Results: The median age of the cohort was 36 years old, with 61.2% being male. …”
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Learning from nature : experimental observation of mimosa pudica by Zhang, Yi

“…The five-number summary includes: the minimum (0th percentile or Q0), the first quartile (25th percentile or Q1), the sample median (50th percentile or Q2), the third quartile (75th percentile or Q3), and the maximum (100th percentile or Q4). …”
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Preliminary assessment of the Healthy Early Life Moments (HELMS) webinars in empowering Developmental Origins of Health and Disease (DOHaD) concept among healthcare professionals -... by Ku, Chee Wai, Ng, Roderica R. G., Chang, Ting Yu, Lim, Celeste H. F., Zheng, Ruther Teo, Ma, Weini, Chua, Mei Chien, Chan, Jerry K. Y., Yap, Fabian, Loy, See Ling

“…We also collected and analyzed data on webinar registration and attendance, participants’ profession and organizational affiliations, and post-webinar survey responses. Results: The median webinar attendance rate was 59.6 % (25th–75th percentile: 58.4–60.8 %). …”
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Transition probabilities of diabetic retinopathy and death in an Asian population with diabetes by Seshasai, Sudarshan, He, Feng, Lam, Betty, Hamzah, Haslina, Cheng, Ching-Yu, Li, Jialiang, Wong, Tien Yin, Tan, Gavin Siew Wei, Sabanayagam, Charumathi

“…A multistate Markov model adjusted for age, sex, systolic blood pressure (SBP), diabetes duration, HbA1c, and body mass index (BMI) was applied to estimate annual transition probabilities between four DR states (no, mild, moderate, and severe/proliferative) and death, and the mean sojourn time in each state. Results: The median assessment interval was 12 months, with most patients having 3 assessments. …”
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Acute inflammatory diseases of the central nervous system after SARS-CoV-2 vaccination by Francis, AG, Elhadd, K, Camera, V, Ferreira Dos Santos, M, Rocchi, C, Adib-Samii, P, Athwal, B, Attfield, K, Barritt, A, Craner, M, Fisniku, L, Iversen, AKN, Leach, O, Matthews, L, Redmond, I, O'Riordan, J, Scalfari, A, Tanasescu, R, Wren, D, Huda, S, Leite, MI, Fugger, L, Palace, J

“…</p> <p><strong>Results:&nbsp;</strong>Of 25 patients identified (median age 38 years, 14 female), 12 (48%) had MOG antibodies (MOGIgG+), 2 (8%) had aquaporin 4 antibodies (AQP4IgG+), and 11 (44%) had neither. …”

Atmospheric characterization of cold exoplanets using a 1.5-m coronagraphic space telescope by Maire, Anne-Lise, Galicher, Raphael, Boccaletti, Anthony, Baudoz, Pierre, Schneider, Jean, Stam, Daphne, Cahoy, Kerri, Traub, Wes

“…We find that the characterization of the main planetary properties (identification of molecules, effect of metallicity, presence of clouds and type of surfaces) would require a median signal-to-noise ratio of at least 30. In the case of a solar-type star <10 pc, SPICES will be able to study Jupiters and Neptunes up to -5 and -2 AU respectively, because of the drastic flux decrease with separation. …”
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Event rates and incidence of post-COVID-19 condition in hospitalised SARS-CoV-2 positive children and young people and controls across different pandemic waves: exposure-stratified... by Pazukhina, E, Rumyantsev, M, Baimukhambetova, D, Bondarenko, E, Markina, N, El-Taravi, Y, Petrova, P, Ezhova, A, Andreeva, M, Iakovleva, E, Bobkova, P, Pikuza, M, Trefilova, A, Abdeeva, E, Galiautdinova, A, Filippova, Y, Bairashevskaia, A, Zolotarev, A, Bulanov, N, DunnGalvin, A, Chernyavskaya, A, Kondrikova, E, Kolotilina, A, Gadetskaya, S

“…</p> <br> <p><strong>Results:</strong> Of 2595 CYP with confirmed COVID-19, 1707 (65.7%) participated in follow-up interviews, with 1183/1707 (69%) included in the final ‘matched’ analysis. The median follow-up time post-discharge was 6.7 months. …”