Incidence and mortality rates of 14 site-specific infectious diseases in 10 diverse areas of China: findings from China Kadoorie Biobank, 2006-2018 by Huang, R, Kartsonaki, C, Turnbull, I, Pei, P, Chen, Y, Liu, J, Du, H, Sun, D, Yang, L, Barnard, M, Lv, J, Yu, C, Chen, J, Li, L, Chen, Z, Bragg, F

“…The observed burden of, and disparities in, site-specific infections can inform targeted prevention efforts.…”

Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults by Ho, Vanda W. T., Boon, Low Heng, Cui, Jianzhou, Juequn, Zhou, Shunmuganathan, Bhuvaneshwari, Gupta, Rashi, Tan, Nikki Y. J., Qian, Xinlei, Purushotorman, Kiren, Fong, Siew-Wai, Renia, Laurent, Ng, Lisa F. P., Angeli, Veronique, Chen, Jinmiao, Kennedy, Brian K., Ong, Catherine W. M., Macary, Paul A.

Subjects: Get full text

The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
Get full text

Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens by Barrett, JR, Silk, SE, Mkindi, CG, Kwiatkowska, KM, Hou, MM, Lias, AM, Kalinga, WF, Mtaka, IM, McHugh, K, Bardelli, M, Davies, H, King, LDW, Edwards, NJ, Chauhan, VS, Mukherjee, P, Rwezaula, S, Chitnis, CE, Olotu, AI, Minassian, AM, Draper, SJ, Nielsen, CM

“…Notably, a higher frequency of vaccine-specific (putatively long-lived) plasma cells was detected in the bone marrow of these delayed boosting vaccinees by ELISPOT and correlated strongly with serum IgG. …”

Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals by Goh, Yun Shan, Rouers, Angeline, Fong, Siew-Wai, Zhuo, Nicole Ziyi, Hor, Pei Xiang, Loh, Chiew Yee, Huang, Yuling, Neo, Vanessa Kexin, Kam, Isaac Kai Jie, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Lee, Raphael Tze Chuen, Pada, Surinder, Sun, Louisa Jin, Ong, Desmond Luan Seng, Somani, Jyoti, Lee, Eng Sing, Maurer-Stroh, Sebastian, Wang, Cheng-I., Leo, Yee Sin, Ren, Ee Chee, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

Get full text

Understanding lived experiences of bereaved parents of children with chronic life-threatening Illness : towards a culture-specific and meaning-oriented narrative E-writing intervention (NeW-I) for anticipatory grief support in Singapore by Dutta, Oindrila

“…This doctoral research is a first-of-its kind series of studies that comprehensively and holistically examined the lived experience of bereaved parents globally and in Singapore; building on this novel body of knowledge, it further developed and piloted a culture-specific and evidence-based intervention to support parent-caregivers of children with chronic life-threatening illness. …”
Get full text

Dialectic of digital enlightenment: reclaiming radical philosophy for our times by Nayak, Bhabani Shankar

Subjects:

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Schumacher, AE, Kyu, HH, Aali, A, Almidani, O, Bandyopadhyay, S, Basnyat, B, Maude, RJ, Bennett, D, Browne, AJ, Dolecek, C, Dunachie, SJ, Newton, CRJ, Rodriguez, JAB

“…Life expectancy was calculated using age-specific mortality rates and standard demographic methods. …”

16.355J / ESD.355J Advanced Software Engineering, Fall 2002 by Leveson, Nancy

Subjects: Get full text

16.842 Fundamentals of Systems Engineering, Fall 2009 by de Weck, Olivier

Subjects: Get full text

Design and Construction of Artificial Extracellular Matrix (aECM) Proteins from Escherichia coli for Skin Tissue Engineering by Low, Pearlie Si Jia, Tjin, Monica Suryana, Fong, Eileen

Subjects: Get full text
Get full text

21W.780 Communicating in Technical Organizations, Spring 2006 by Barrett, Edward C., Bentley, Frank

Subjects: Get full text

16.885J / ESD.35J Aircraft Systems Engineering, Fall 2003 by Hansman, Robert John, Liebeck, Robert H, Murman, Earll M., 1942-, Haggerty, Allen C

Subjects: Get full text

16.01-04 Unified Engineering I, II, III, & IV, Fall 2003-Spring 2004 by Hall, Steven Ray, Coleman, Charles P, Drela, Mark, Lundqvist, Ingrid Kristina, Spearing, S Mark, Waitz, Ian A, Young, Peter W

Subjects: Get full text

Improving the productivity of high-level synthesis by advancing reuseability and verifiability by Yang, Liwei

“…Following algorithmic specifications, designers perform architectural specification including hardware/software (HW/SW) partitioning. …”
Get full text

Discovery of stabilized functional mutants of human aquaporin 1 by Soh, Miao Yi

“…. ~ 5% of mutants from a total of 2816 screened from thirty-three 96-well plates were identified after a series of initial and verification screens. In future, we hope to characterize these mutants for increased stability as they may be useful in structural studies, drug discovery in human cancers related to AQP1 overexpression as well as in biotechnological applications, such as water purification, in particular.…”
Get full text

Feasibility of Vector Instruction-Set Semantics Using Abstract Monads by De Belen, Arthur Reiner

“…I answer this question with a tentative “yes”, backed by a partial specification in Haskell of a small but nontrivial subset of this vector extension, a translation of the same specification into Coq using hs-to-coq², and work towards demonstrating the utility of this specification.…”
Get full text

Conformational design characterization of a truncated diamine oxidase by Razali, Nur Nadia

“…High purification yield of 88% was obtained for mini protein fusion tagged (His-tagged + mature mini protein). …”
Get full text

Solublizing the insoluble by Ang, Grace Pei Ting

“…Biochemical and structural research on target proteins has often been hindered by the difficulties faced in protein purification as proteins are known to aggregate in unsuitable environments. …”
Get full text

Co-translational integration of the light harvesting complex II and its associated pigments into polymeric membranes by Zapf, Thomas

“…Centrifugal microfiltration in means of polymersome purification as well as the development of a novel silica nanoparticles based purification method are further presented in this work. …”
Get full text