Immuno-protective effect of commercial IBD vaccines against emerging novel variant infectious bursal disease virus in specific-pathogen-free chickens by Aliyu, Hayatuddeen Bako, Hamisu, Tasiu Mallam, Hair-Bejo, Mohd, Omar, Abdul Rahman, Ideris, Aini

“…Objective: This study examined the immune protection of immune-complex (Vaccine A) and attenuated live (Vaccine B) IBD vaccines in specific-pathogen-free (SPF) chickens against a novel Malaysian variant IBD virus (vaIBDV) challenge. …”
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Sequence- and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analog by Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Meng, Zhenyu, Ong, Alan Ann Lerk, Wang, Zhenzhang, Lu, Yunpeng, Xia, Kelin, Prabakaran, Mookkan, Chen, Gang

“…We have successfully developed nucleobase-modified dsRNA-binding PNAs (dbPNAs) to facilitate structure-specific and selective recognition of dsRNA over single-stranded RNA (ssRNA) and dsDNA regions at near-physiological conditions. …”
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Exploring the induction of preproinsulin-specific Foxp3+ CD4+ Treg cells that inhibit CD8+ T cell-mediated autoimmune diabetes by DNA vaccination by Stifter, Katja, Schuster, Cornelia, Schlosser, Michael, Boehm, Bernhard Otto, Schirmbeck, Reinhold

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Incidence and mortality rates of 14 site-specific infectious diseases in 10 diverse areas of China: findings from China Kadoorie Biobank, 2006-2018 by Huang, R, Kartsonaki, C, Turnbull, I, Pei, P, Chen, Y, Liu, J, Du, H, Sun, D, Yang, L, Barnard, M, Lv, J, Yu, C, Chen, J, Li, L, Chen, Z, Bragg, F

“…The observed burden of, and disparities in, site-specific infections can inform targeted prevention efforts.…”

Mapping epigenetic modifications by sequencing technologies by Chen, X, Xu, H, Shu, X, Song, C-X

“…With the rapid development of sequencing technologies, scientists are able to detect specific epigenetic modifications with various quantitative, high-resolution, whole-genome/transcriptome approaches. …”

Surface modification and characterization of polypropylene fibers by Tan, Terry Jian Hong.

“…This surface modification comes with physical etching of the surface as well as alterations to the chemical characteristics of the fiber surface. …”
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Bio-modification of sand for cement grouting by Ng, Samuel Joel Rui Ming

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Electrochemical modification of electrodes with metal nanoparticles by Mavrokefalos, C

“…The electrochemical activity of these materials was investigated in order firstly to expand the knowledge of diamond electrochemistry and secondly to establish an understanding of how the electrochemical modification with metal nanoparticles of core-shell structure impacts their electrochemical performance.…”

Elucidating the effects of DNA modification on transcription by Yavorska, O

“…<p>DNA modifications play important roles in genome function of vertebrates. 5-methylcytosine (mC) has been extensively studied over the last 50 years as the most common covalent DNA modification, present at roughly 70% of CpGs in the human genome. …”

Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults by Ho, Vanda W. T., Boon, Low Heng, Cui, Jianzhou, Juequn, Zhou, Shunmuganathan, Bhuvaneshwari, Gupta, Rashi, Tan, Nikki Y. J., Qian, Xinlei, Purushotorman, Kiren, Fong, Siew-Wai, Renia, Laurent, Ng, Lisa F. P., Angeli, Veronique, Chen, Jinmiao, Kennedy, Brian K., Ong, Catherine W. M., Macary, Paul A.

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The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
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Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens by Barrett, JR, Silk, SE, Mkindi, CG, Kwiatkowska, KM, Hou, MM, Lias, AM, Kalinga, WF, Mtaka, IM, McHugh, K, Bardelli, M, Davies, H, King, LDW, Edwards, NJ, Chauhan, VS, Mukherjee, P, Rwezaula, S, Chitnis, CE, Olotu, AI, Minassian, AM, Draper, SJ, Nielsen, CM

“…Here, using flow cytometry – including agnostic definition of B cell populations with the clustering tool CITRUS – we report enhanced induction of DBPRII-specific plasma cell and memory B cell responses in protein/adjuvant versus viral vector vaccinees. …”

Role of posttranslational modifications of histone proteins in epigenetics by Raj, R

“…<p>Nature has evolved an additional level of genetic regulation by-passing direct changes in genetic code through the means of posttranslational modifications (PTMs) of nucleobases and histone proteins. …”

Model reduction and stochastic analysis of the histone modification circuit by Bruno, Simone, Williams, Ruth J., Del Vecchio, Domitilla

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Residual soil modification using ureolytic bacteria and lime / by Low, Yee Hwa 1991-, author 644926, Khairul Anuar Kassim, supervisor 562339, Fakulti Kejuruteraan Awam 8022

Biophysical studies of oligonucleotides containing duplex stabilising modifications by Marafini, P

“…To enable easier access to this modification, a reductive amination labelling strategy was developed to produce pyrene-functionalised nucleobase analogues which allowed an easier synthesis of X-pyrene. …”

Investigating the impact of ligand modification on luminescent lanthanide complexes by Simms, CH

“…It describes the various methods in which ligand choice and modification has allowed for the development of responsive luminescent lanthanide probes.…”

Effect of dye modification on the sorption of copper by coconut husk by Low, K. S., Lee, C. K., Wong, S. L.

“…The equilibrium data obey the Langmuir isotherms for the natural and dye-coated husk-Cu systems. Dye modification led to an enhancement in Cu sorption.…”

Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals by Goh, Yun Shan, Rouers, Angeline, Fong, Siew-Wai, Zhuo, Nicole Ziyi, Hor, Pei Xiang, Loh, Chiew Yee, Huang, Yuling, Neo, Vanessa Kexin, Kam, Isaac Kai Jie, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Lee, Raphael Tze Chuen, Pada, Surinder, Sun, Louisa Jin, Ong, Desmond Luan Seng, Somani, Jyoti, Lee, Eng Sing, Maurer-Stroh, Sebastian, Wang, Cheng-I., Leo, Yee Sin, Ren, Ee Chee, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

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Modification of the contact surfaces for improving the puncture resistance of laminar structures by Wang, Pengfei, Yang, Jinglei, Li, Xin, Liu, Mao, Zhang, Xin, Sun, Dawei, Bao, Chenlu, Gao, Guangfa, Yahya, Mohd Yazid, Xu, Songlin

“…The coated -surfaces improved the specific energy dissipation by approximately 15~40% relative to the dry-contact configuration for both single-layer and double-layer configurations, and specific energy dissipations of double-layer configurations were 20~30% higher than those of the single-layer configurations. …”
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