DNA extraction methodologies for ultra long nanopore sequencing to determine chromosome specific rodent telomere lengths by Kidd, Elliot, Mooruth, Ravi, Meimaridou, Eirini, Walley, Andrew, Fairbrother, Una

“…Direct sequencing of highly repetitive stretches of DNA is difficult, using specific DNA extraction techniques and adaptive sampling and tagging approaches for targeted enrichment has generated chromosome specific ultralong reads in rodents.…”
Get full text

An epitope-specific LGI1-autoantibody enhances neuronal excitability by modulating Kv1.1 channel by Extrémet, J, El Far, O, Ankri, N, Irani, SR, Debanne, D, Russier, M

“…Patient-derived recombinant monoclonal antibodies (mAbs) are ideal reagents to study whether domain-specific LGI1-autoantibodies induce epileptiform activities in neurons and their downstream mechanisms. …”

Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…To better understand ventricle-specific molecular changes influencing heart failure development, we first performed unbiased quantitative mass spectrometry on pre-mortem non-diseased human myocardium to compare the metabolome and proteome between the normal left and right ventricles. …”

Maternal Death Surveillance and Response in Sudan: an evidence-based, context-specific optimisation to improve maternal care by Altijani Osman Abbakar, N

Structural dynamics of the ubiquitin specific protease UPS30 in complex with a cyanopyrrolidine-containing covalent inhibitor by O’Brien, DP, Jones, HBL, Shi, Y, Guenther, F, Vendrell, I, Viner, R, Brennan, PE, Mead, E, Zarganes-Tzitzikas, T, Davis, JB, Pinto-Fernández, A, England, KS, Murphy, EJ, Turnbull, AP, Kessler, BM

A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment by Viz-Lasheras, S, Gómez-Carballa, A, Bello, X, Rivero-Calle, I, Dacosta, AI, Kaforou, M, Habgood-Coote, D, Cunnington, AJ, Emonts, M, Herberg, JA, Wright, VJ, Carrol, ED, Paulus, SC, Zenz, W, Kohlfürst, DS, Schweintzger, N, Van der Flier, M, de Groot, R, Schlapbach, LJ, Agyeman, P, Pollard, AJ, Fink, C, Kuijpers, TT, Anderson, S

“…Current diagnostic tests are time-consuming and have low specificity, leading clinicians to administer empirical antibiotics. …”

Identification and validation of novel breed-specific biomarker for the purpose of village chicken authentication using genomics approaches by Nematbakhsh, Sara, Pei, Chong Pei, Nordin, Noordiana, Selamat, Jinap, Idris, Lokman Hakim, Abdull Razis, Ahmad Faizal

“…Therefore, developing a breed-specific authentication method is crucial for preventing food fraud in the poultry industry. …”
Get full text

Constructing quantum angular momentum l̂3 in a specific direction by using the U(1) group by Rosli, Ahmad Aqwa, Mohd Shah, Nurisya

“…The purpose of this work is to investigate the mathematical structure of finite quantum angular momentum in a specific direction L3 which can be constructed from the representation of the U(1) group. …”
Get full text

Analyzing the challenges of developing English for Specific Purpose (ESP) courses for Sino-Foreign Cooperative Educational Programs by Huang, Zizhe, Mustakim, Siti Salina, Ghazali, Norliza

“…The development of English for Specific Purposes (ESP) courses is directly related to the quality of talent cultivation in Sino-foreign cooperative educational programs. …”
Get full text

Effects of functional training on tennis-specific physical fitness and functional movement screen in junior tennis players by Xiao, Wensheng, Bai, Xiaorong, Soh, Kim Geok, Zhang, Yang

“…At baseline, after six weeks, and after 12 weeks (T12), the participants' tennis-specific physical fitness and functional movement screen (FMS) were evaluated. …”
Get full text

Bioinformatics tools assist in the screening of potential porcine-specific peptide biomarkers of gelatin and collagen for halal authentication by Abdul Shukor, Muhd Syarafuddin, Abdullah, Mohd Faiz Foong, Zainal Abidin, Siti Aimi Sarah, Yuswan, Mohd Hafis, Mohd Ismail, Azilawati

“…This study aims to identify the specific peptide biomarkers by employing bioinformatics technique which can be applied to identify gelatin and collagen sources with the aid of mass spectrometry. …”
Get full text

A formal methodology for verifying side-channel vulnerabilities in cache architectures by Jiang, Ke, Zhang, Tianwei, Sanan, David, Zhao, Yongwang, Liu, Yang

Subjects: Get full text

Heteroatom-doped microporous carbon nanosheets derived from pentaerythritol-melamine for supercapacitors and CO₂ capture by Hu, Xiaochun, Luo, Yuqing, Wu, Xianyue, Niu, Jiabin, Tan, Mingwu, Sun, Zhiqiang, Liu, Wen

Subjects: Get full text

Surface modification of oriented glass fibers for improving the mechanical properties and flame retardancy of polyamide 12 composites printed by powder bed fusion by Hou, Yanbei, Gao, Ming, An, Ran, Tey, Wei Shian, Li, Boyuan, Chen, Jiayao, Zhao, Lihua, Zhou, Kun

“…This work presents a feasible and practical approach for addressing these two issues, by surface modification of GF with layered double hydroxide (LDH) to synthesize LDH@GF hybrids. …”
Get full text

Poly(ß-hydroxy thioether)s: synthesis through thiol-epoxy ‘click’ reaction and post-polymerization modification to main-chain polysulfonium salts by Stuparu, Mihaiela Corina, Khan, Anzar

Get full text

N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 by Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.

“…N6-Methyladenosine (m6A) is currently one of the most intensively studied post-transcriptional modifications in RNA. Due to its critical role in epigenetics and physiological links to several human diseases, it is also of tremendous biological and medical interest. …”
Get full text
Get full text

Computational analysis and prediction of specific genomic regions forming R-loop structure and chromosomal variations associated with cancer by Wongsurawat, Thidathip

“…Integrative genomics analyses suggested that RLFSs could play a role in gene regulation, AID/APOBEC-mediated editing/mutagenesis, alternative splicing, and epigenetic modifications, and also associate with mutations in cancer, neurodegenerative diseases and mental disorders. …”
Get full text

Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells by Fang, Zijian, Chen, Shiqian, Manchanda, Yusman, Bitsi, Stavroula, Pickford, Philip, David, Alessia, Shchepinova, Maria M., Corrêa, Ivan R., Jr., Hodson, David J., Broichhagen, Johannes, Tate, Edward W., Reimann, Frank, Salem, Victoria, Rutter, Guy A., Tan, Tricia, Bloom, Stephen R., Tomas, Alejandra, Jones, Ben

“…These observations provide insights into how ligand- and genotype-specific factors can influence GLP-1R trafficking.…”
Get full text

Growth hormone increases BDNF and mTOR expression in specific brain regions after photothrombotic stroke in mice by Sanchez-Bezanilla, Sonia, Beard, Daniel J., Hood, Rebecca J., Åberg, N. David, Crock, Patricia, Walker, Frederick R., Nilsson, Michael, Isgaard, Jörgen, Ong, Lin Kooi

“…These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.…”
Get full text

Investigating the signaling properties of myeloid specific integrin αMβ2 (CD11BCD18) by Ong, Li Teng

“…Apart from its well-established role as a phagocytic receptor, the myeloid specific integrin αMβ2 (CD11bCD18) is involved in cell migration, leukocyte survival and immune tolerance. …”
Get full text