Left Atrial Appendage Occlusion: Current Stroke Prevention Strategies and a Shift Toward Data-Driven, Patient-Specific Approaches by Mendez, Keegan, Kennedy, Darragh G., Wang, Dee Dee, O’Neill, Brian, Roche, Ellen T.

“…We highlighted recent advances in computed tomography imaging, preprocedural planning, computational modeling, and novel additive manufacturing techniques, which represent the tools needed for a paradigm shift toward patient-centric LAA occlusion. …”
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Percutaneous Intratumoral Immunoadjuvant Gel Increases the Abscopal Effect of Cryoablation for Checkpoint Inhibitor Resistant Cancer by Som, Avik, Rosenboom, Jan‐Georg, Wehrenberg‐Klee, Eric, Chandler, Alana, Ndakwah, Gabrielle, Chen, Eric, Suggs, Jack, Morimoto, Joshua, Kim, Jonathan, Mustafa, Abdul Rehman, Marcos‐Vidal, Asier, Fintelmann, Florian J., Basu, Arijit, Langer, Robert, Traverso, Giovanni, Mahmood, Umar

“…To address these shortcomings, an injectable thermoresponsive gel‐based controlled release formulation is developed for the FDA‐approved Toll‐like‐receptor 7 (TLR7) agonist imiquimod (“Imigel”) that forms a tumor‐resident depot upon injection and contains a contrast agent for visualization under computed tomography (CT). The poly‐lactic‐<jats:italic>co</jats:italic>‐glycolic acid‐polyethylene glycol‐poly‐lactic‐<jats:italic>co</jats:italic>‐glycolic acid (PLGA‐PEG‐PLGA)‐based amphiphilic copolymer gel's underlying micellar nature enables high drug concentration and a logarithmic release profile that is additive with the neo‐antigen release from cryoablation, requiring only a single injection. …”
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Cake formation of bidisperse suspensions in dead-end microfiltration by Han, Qi, Trinh, Thien An, Chew, Jia Wei

“…The evolution of the cake during dead-end microfiltration of different compositions of bidisperse feeds was investigated using network modeling and three-dimensional (3D) optical coherence tomography (OCT) imaging. The foulant particles were latex of two different sizes (namely, 3 and 5 µm) and the membrane was polycarbonate track-etched with nominal diameter of 2 µm. …”
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Microfiltration of oil emulsions stabilized by different surfactants by Trinh, Thien An, Han, Qi, Ma, Yunqiao, Chew, Jia Wei

“…The Optical Coherence Tomography (OCT) was employed to quantify the evolution of fouling, and both the DLVO and XDLVO models were used to quantify the oil droplet-membrane and oil droplet-deposited layer interaction energies. …”
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Accuracy of thoracolumbar pedicle screw insertion based on routine use of intraoperative imaging and navigation by Sundaram, Pirateb Paramasivam Meenakshi, Oh, Jacob Yoong-Leong, Tan, Mark, Nolan, Colum Patrick, Yu, Chun Sing, Ling, Ji Min

“…Methods: Patients who had undergone thoracolumbar pedicle screws insertion using intraoperative imaging and navigation between 2009 and 2017 were retrospectively analyzed. Computed tomography (CT) images acquired after the insertion of pedicle screws were analyzed for breach of the pedicle wall. …”
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Fouling and mitigation mechanisms during direct microfiltration and ultrafiltration of primary wastewater by Hube, Selina, Wang, Jingwei, Sim, Lee Nuang, Ólafsdóttir, Dagmar, Chong, Tzyy Haur, Wu, Bing

“…Several types of MF and UF membranes were examined by threshold flux determination, and two types of membranes (MF, 0.08 μm; UF, 100 kDa) were chosen for exploring membrane fouling mechanisms at different feed pressures via both fouling resistance analysis and optical coherence tomography (OCT) observation. The results revealed that both MF and UF displayed three-stage fouling behaviors, i.e., initial intermediate pore blocking followed by two-stage cake filtration. …”
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Towards indicating human skin state in vivo using geometry-dependent spectroscopic contrast imaging by Ni, Guangming, Ge, Xin, Liu, Lin, Zhang, Jing, Wang, Xiangzhou, Liu, Juanxiu, Liu, Linbo, Liu, Yong

“…We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography (SμOCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of 700 - 950 nm. …”
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Targeted pancreatic beta cell imaging for early diagnosis by Cong, Goh Zheng, Ghosh, Krishna Kanta, Mishra, Sachin, Gulyás, Miklós, Kovács, Tibor, Máthé, Domokos, Padmanabhan, Parasuraman, Gulyás, Balázs

“…This includes membrane protein on pancreatic beta cells whereby specific probes are designed for different imaging modalities mainly magnetic resonance imaging, positron emission tomography and fluorescence imaging. Direct imaging of insulin is also explored though probes synthesized for such function are relatively fewer. …”
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Longitudinal assessment of the choroidal vascularity index in eyes with branch retinal vein occlusion-associated cystoid macular edema by Pant, Praruj, Kundu, Anita, Rathinavelu, Jay K., Wei, Xin, Agrawal, Rupesh, Stinnett, Sandra S., Kim, Jane S., Thomas, Akshay S., Fekrat, Sharon

“…In recent literature, choroidal vascularity index (CVI) has been proposed to be an enhanced depth imaging optical coherence tomography (EDI-OCT) metric that may help characterize choroidal vascular changes in the setting of retinal ischemia, and potentially prognose visual outcomes and treatment patterns for patients with BRVO-related CME. …”
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Deep learning-enabled 3D multimodal fusion of cone-beam CT and intraoral mesh scans for clinically applicable tooth-bone reconstruction by Liu, Jiaxiang, Hao, Jin, Lin, Hangzheng, Pan, Wei, Yang, Jianfei, Feng, Yang, Wang, Gaoang, Li, Jin, Jin, Zuolin, Zhao, Zhihe, Liu, Zuozhu

“…High-fidelity three-dimensional (3D) models of tooth-bone structures are valuable for virtual dental treatment planning; however, they require integrating data from cone-beam computed tomography (CBCT) and intraoral scans (IOS) using methods that are either error-prone or time-consuming. …”
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3D patient specific instrumentation for high tibial osteotomy by Wong, Gina Khay Fong

“…Bone models are created from computed tomography (CT) scans which are specimens provided by the Singapore General Hospital (SGH). …”
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Corrosion and stress corrosion cracking resistances of the 17-4 precipitation hardened martensitic stainless steel additively manufactured using binder jet printing by Xiong, Yida, Radhakrishnan, Jayaraj, Huang, Sheng, Chua, Yusheng, Shi, Wei, Ramamurty, Upadrasta

“…Detailed analyses (including the X-ray computed tomography) show that crack bridging induced by the δ-ferrite phase, which has superior corrosion resistance compared to the martensite, is the reason for the BJP alloy's SCC resistance. …”
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Multi-harmonic scanning near-field optical microscopy by Dong, Zhaogang

“…The system is demonstrated to have the capabilities of improving optical imaging resolution, identifying and reducing artifacts, and achieving near-field tomography. The key contributions of this PHD thesis can be summarized as follows: Firstly, a multi-harmonic SNOM technology is proposed by utilizing the intrinsic harmonics in the mechanical oscillation of the tuning fork probe. …”
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A network-based approach to interpreting pore blockage and cake filtration during membrane fouling by Han, Qi, Li, Weiyi, Trinh, Thien An, Liu, Xin, Chew, Jia Wei

“…Although limited fouling cases were examined in the current study, it is expected that the network model developed here can be readily applied to study more complex phenomena involved in a membrane filtration process (e.g., shear-induced diffusion), and the associated insights would be significantly enhanced when coupled with more advanced fouling characterization techniques (e.g., Optical Coherence Tomography).…”
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Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting by McAteer, MA, McGowan, DR, Cook, GJR, Leung, HY, Ng, T, O’Connor, JPB, Aloj, L, Barnes, A, Blower, PJ, Brindle, KM, Braun, J, Buckley, C, Darian, D, Evans, P, Goh, V, Grainger, D, Green, C, Hall, MG, Harding, TA, Hines, CDG, Hollingsworth, SJ, Cristinacce, PLH, Illing, RO, Lee, M, Patel, N, Higgins, GS

“…Background: The clinical translation of positron emission tomography (PET) radiotracers for cancer management presents complex challenges. …”

18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…This includes the application of organofluorine in both medicinal chemistry and positron emission tomography. <b>Chapter 2</b> describes a novel silver-mediated ¹⁸F-labelling of Ar-SCF3, Ar OCF3 and Ar-OCF2H, including [¹⁸F]Riluzole, the ¹⁸F labelled version of a drug for treatment of amyotrophic lateral sclerosis (ALS). …”

Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs by Liu, Xili, Moscvin, Maria, Oh, Seungeun, Chen, Tianzeng, Choi, Wonshik, Evans, Benjamin, Rowell, Sean M., Nadeem, Omar, Mo, Clifton C., Sperling, Adam S., Anderson, Kenneth C., Yaqoob, Zahid, Bianchi, Giada, Sung, Yongjin

“…For the dry mass measurement, we use two types of phase-sensitive optical microscopy techniques: digital holographic tomography and computationally enhanced quantitative phase microscopy. …”
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In-situ monitoring of oil emulsion fouling in ultrafiltration via electrical impedance spectroscopy (EIS): influence of surfactant by Tian, Ju, Trinh, Thien An, Kalyan, Muppalla Naga, Ho, Jia Shin, Chew, Jia Wei

“…For instance, a recent study showed that the fouling trends revealed by optical coherence tomography (OCT) were incongruent with the flux decline trends. …”
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Simultaneous super-resolution and classification of lung disease scans by Heba M. Emara, Mohamed R. Shoaib, Walid El-Shafai, Mohamed Elwekeil, Ezz El-Din Hemdan, Mostafa M. Fouda, Taha E. Taha, Adel S. El-Fishawy, El-Sayed M. El-Rabaie, Fathi E. Abd. El-Samie

“…Chest X-ray and computed tomography (CT) have the potential to serve as effective screening tools for lower respiratory infections, but the use of artificial intelligence (AI) in these areas is limited. …”
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Towards depth-resolved multi-cubic-centimeter field of view endoscopic camera for intraoperative nerve identification. by Yoon, Yong-Chul

“…Polarization-based optical coherence tomography (OCT) approaches to nerve visualization would inherently mitigate each of these translational challenges. …”
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