Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol by Svensson, Jonas E., Bolin, Martin, Thor, Daniel, Williams, Pete A., Brautaset, Rune, Carlsson, Marcus, Sörensson, Peder, Marlevi, David, Spin-Neto, Rubens, Probst, Monika, Hagman, Göran, Morén, Anton Forsberg, Kivipelto, Miia, Plavén-Sigray, Pontus

“…The primary endpoint will be change in cerebral glucose uptake, measured using [18F]FDG positron emission tomography. Secondary endpoints include changes in cognitive measures, markers in cerebrospinal fluid as well as cerebral blood flow measured using magnetic resonance imaging. …”
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3D printed bio-models for medical applications by Yap, Yee Ling, Tan, Edgar Yong Sheng, Tan, Joel Heang Kuan, Peh, Zhen Kai, Low, Xue Yi, Yeong, Wai Yee, Tan, Colin Siang Hui, Laude, Augustinus

“…Design/methodology/approach - Different data sources including engineering drawing, computed tomography (CT), and optical coherence tomography (OCT) were converted to a printable data format. …”
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Development of algorithms for high performance digital image processing with applications to medical imaging by Zhang, Cishen

“…We have conducted research in two areas of medical imaging which are ultrasound imaging and computed tomography (CT) imaging. In ultrasound imaging, we introduce a new tissue model where the inclusion of more realistic physical analysis in the received pulse-echo pressure field shows that there are two different natures of noise sources existing in the received ultrasound RF echo. …”
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Multi-harmonic scanning near-field optical microscopy by Dong, Zhaogang

“…By multiplying the second harmonic SNOM signal and the topography signal, topographical artifact is calculated and reduced from the original DC SNOM signal. …”
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Deformation and its surface expression in stressed planetary materials by Seltzer, Cassandra

“…This work models how tidal stresses interact with local topographic stresses to create fracture across Titan’s crust, creating pathways for sediment generation and fluid transport.…”
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The development of orogenic plateaus : Plateaus: case studies examining relationships between tectonics, crustal strength, surface deformation, and plateau morphology by Cook, Kristen Lee

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Migration and phenotype control of human dermal fibroblasts by electrospun fibrous substrates by Chen, Huizhi, Lui, Yuan Siang, Tan, Zhen Wei, Lee, Justin Yin Hao, Tan, Nguan Soon, Tan, Lay Poh

“…To design functional scaffolds, it is important to explore the interactions between scaffold topographic features and cellular responses, especially directional migration and phenotypic changes, which are critical functional aspects during wound healing. …”
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Epstein-Barr viral latent and early antigen serology in nasopharyngeal carcinoma by Tan, Timothy Ter Ming.

“…Clinically, it can be detected by an experienced medical practitioner using fibreoptic endoscopy, computer-assisted tomography or through serological tests. Serological testing detects the presence of specific antibodies to the Epstein-Barr virus, which is a crucial aetiological factor in the pathogenesis of the disease. …”
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Imaging sodium dendrite growth in all‐solid‐state sodium batteries using 23Na T2‐weighted magnetic resonance imaging by Rees, GJ, Spencer Jolly, D, Ning, Z, Marrow, T, Pavlovskaya, GE, Bruce, P

“…A spalling dendritic morphology is observed and confirmed by more conventional post‐mortem analysis; X‐ray tomography and scanning electron microscopy. A significantly larger 23Na T2 for the dendritic growth, compared with the bulk metal electrode, is attributed to increased sodium ion mobility in the dendrite. 23Na T2‐contrast MRI of metallic sodium offers a clear, routine method for observing and isolating microstructural growths and can supplement the current suite of techniques utilised to analyse dendritic growth in all‐solid‐state cells.…”

Correlative light and electron microscopy of telomeric repeat-binding factor 1 in mammalian cells by von Otter, Eric

“…Analysis of the ultrastructure of telomeres by electron tomography reveals a mesoporous meshwork of interconnected chromatin fibers and globular domains. …”
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Piecewise damage model for SiC/SiC composites with multilevel experimental validation by Shi, D, Wang, Z, Marrow, J, Liu, C, Wan, F, Yang, X

“…First, the geometric information of the microstructure was acquired using scanning electron microscopy (SEM) and X-ray computed tomography (X-CT). High-precision and total-factor finite element models were established, and a piecewise damage model was introduced to simulate in detailing the initiation and propagation of damage. …”

A multimodal multidomain multilingual medical foundation model for zero shot clinical diagnosis by Liu, F, Li, Z, Yin, Q, Huang, J, Luo, J, Thakur, A, Branson, K, Schwab, P, Yin, B, Wu, X, Zheng, Y, Clifton, DA

“…Typically, clinical diagnosis using radiology images involves disease reporting and classification, where the former is a multimodal task whereby textual reports are generated to describe clinical findings in images, as are common in various domains, e.g., chest X-ray or computed tomography. Existing approaches are mainly supervised, the quality of which heavily depends on the volume and quality of available labeled data. …”

Nonlinear optical imaging investigations at the micro-scale by Lim, Ken Choong

“…Furthermore, the NLSM was used to perform 3D tomographic imaging on electroluminescent displays printed on a plastic substrate. …”
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Long-term slip rate of the southern San Andreas Fault from 10Be-26Al surface exposure dating of an offset alluvial fan by Ryerson, Frederick J., Van der Woerd, Jérôme, Klinger, Yann, Sieh, Kerry, Tapponnier, Paul, Mériaux, Anne-Sophie

“…Field mapping complemented with topographic data, air photos and satellite images allows precise determination of piercing points across the fault zone that are used to measure an offset of 565 ± 80 m. …”
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Global whole lithosphere isostasy : implications for surface elevations, structure, strength, and densities of the continental lithosphere by Lamb, Simon, Moore, James Daniel Paul, Perez-Gussinye, Marta, Stern, Tim

“…We show that a crustal model for Antarctica, assuming WLI and using these density contrasts, provides a close fit to estimates of crustal thickness from surface wave tomography and gravity observations. We use a global model of WLI as a framework to assess factors controlling topography, showing that plausible regional variations in crustal and mantle densities, together with uncertainties in the crustal and conductive lithospheric thicknesses, are sufficient to account for global elevations without invoking dynamic topography greater than a few hundred meters. …”
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Investigation of low coherence interferometry techniques for biomedical applications by Chow, Tzu Hao

“…An optical coherence tomography (OCT) system based on LCI principles was designed and implemented to detect virus infection in orchid leaves. …”
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3D printing of multi-material bio-models by Low, Xue Yi

“…Meanwhile, a 3D distal tibia model was constructed from Computerized Tomography (CT) scan and duplicated using Fused Deposition Modeling (FDM) for diagnosis and treatment analysis. …”
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Kinematics of Active Deformation Across the Western Kunlun Mountain Range (Xinjiang, China) and Potential Seismic Hazards Within the Southern Tarim Basin by Guilbaud, Christelle, Simoes, Martine, Barrier, Laurie, Laborde, Amandine, Van der Woerd, Jérôme, Li, Haibing, Tapponnier, Paul, Coudroy, Thomas, Murray, Andrew

“…To quantify the rate of active deformation and the potential for major earthquakes in this region, we combine a structural and quantitative morphological analysis of the Yecheng–Pishan fold, along the topographic mountain front in the epicentral area. Using a seismic profile, we derive a structural cross section in which we identify the fault that broke during the Pishan earthquake, an 8–12 km deep blind ramp beneath the Yecheng–Pishan fold. …”
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Complexities of the San Andreas fault near San Gorgonio Pass : implications for large earthquakes by Yule, Doug, Sieh, Kerry

“…(U/Th)/He thermochronometry supports our interpretation that this south-under-north thickening of the crust has created the region's 3 km of topographic relief. We conclude that future large earthquakes generated along the San Andreas fault in this region will have a multiplicity of mostly specifiable sources having dimensions of 1–20 km. …”
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Medical signal and imaging analysis for mucociliary clearance – ciliary beat frequency by Widiarta, Satriyoga

“…In this paper, the Mucociliary Clearance process in the human respiratory airway is visualized using the Optical Coherence Tomography (OCT), where it focuses mainly on the rate of Ciliary Beat Frequency (CBF). …”
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