Comparing user behavior when targeted based on firm inferred interest vs. user stated interest by Cao, Yiqun(Scientist in business management)Massachusetts Institute of Technology.

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Nanomaterials for biomolecules sensing : germanene modified screen printed electrodes for the chronoamperometric detection of histamine in fish samples by Veronica Pereira

“…High histamine consumption could lead to scombroid poisoning that has serious side effects such as hypertension, vomiting and diarrhoea. …”
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Effects of clozapine-N-oxide and compound 21 on sleep in laboratory mice by Traut, J, Mengual, JP, Meijer, E, McKillop, L, Alfonsa, H, Hoerder-Suabedissen, A, Song, SH, Fehér, KD, Riemann, D, Molnar, Z, Akerman, CJ, Vyazovskiy, VV, Krone, LB

“…This implies that back-metabolism to clozapine is not the sole mechanism underlying side effects of chemogenetic actuators. Therefore, any chemogenetic experiment should include a DREADD-free control group injected with the same CNO, C21, or newly developed actuator. …”

Helicobacter pylori infection can affect energy modulating hormones and body weight in germ free mice by Loke, Mun Fai, Vadivelu, Jamuna, Tan, Tuan Lin, Wong, Whye Yen, Khosravi, Yalda, Seow, Shih Wee, Amoyo, Arlaine Anne, Chiow, Kher Hsin, Poh, Qian Hui, Sentosa, Ignatius Mario Doli, Bunte, Ralph M., Pettersson, Sven

“…Further investigations of possible additional side effects of H. pylori are highly warranted.…”
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In vitro and In vivo photothermal cancer therapeutic effects of gold nanorods modified with mushroom β-glucan by Li, Xiaojie, Zhou, Jiajing, Dong, Xiaonan, Cheng, Wai-Yin, Duan, Hongwei, Cheung, Peter C. K.

“…Intravenous injection of AuNR-Glu nanohybrids followed by irradiation from a NIR-II laser at a safe dose (1.0 W/cm2 for 5 min) in nude mice implanted with HT-29 tumors was effective in significantly reducing the tumor growth, with no obvious harmful side effects, as evidenced by histological analysis of major organs. …”
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Thermal-disrupting interface mitigates intercellular cohesion loss for accurate topical antibacterial therapy by Hu, Benhui, Berkey, Christopher, Feliciano, Timothy, Chen, Xiaohong, Li, Zhuyun, Chen, Chao, Amini, Shahrouz, Nai, Mui Hoon, Lei, Qun-Li, Ni, Ran, Wang, Juan, Leow, Wan Ru, Pan, Shaowu, Li, Yong-Qiang, Cai, Pingqiang, Miserez, Ali, Li, Shuzhou, Lim, Chwee Teck, Wu, Yun-Long, Odom, Teri W., Dauskardt, Reinhold H., Chen, Xiaodong

“…Finally, endowing wound dressing with the TRIM effect via in vivo studies in S. aureus infected mice demonstrates a promising strategy for mitigating the side effects of photothermal therapy against a wide spectrum of bacterial infections, promoting future biointerface design for antibacterial therapy.…”
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Efgartigimod efficacy and safety in refractory myasthenia gravis: UK’s first real-world experience by Moniz Dionísio, J, Ambrose, P, Burke, G, Farrugia, ME, Garcia-Reitboeck, P, Hewamadduma, C, Hill, M, Howard, RS, Jacob, S, Kullmann, D, Leite, MI, Miller, J, Pinto, A, Pritchard, J, Riswick, T, Sathasivam, S, Thambirajah, N, Viegas, S, Norwood, F, Spillane, J

“…The mean intracycle reduction in the MG-ADL score in the first, second, third and fourth cycles were −4.6 to –3.9, −3.4 and −4.2, respectively. Side effects were generally mild. No rescue treatments were required. …”

A Wurster-type covalent organic framework with internal electron transfer-enhanced catalytic capacity for tumor therapy by Liu, Yang, Zhao, Huan, Wang, Shihuai, Niu, Rui, Bi, Shuai, Han, Wang-Kang, Wang, Yinghui, Song, Shuyan, Zhang, Hongjie, Zhao, Yanli

“…Furthermore, MSA-2 is specifically released in response to ROS at the tumor site, minimizing the off-target side effects. More importantly, Co-TB COF-induced STING activation normalizes tumor vasculature and increases the expression of endothelial T cell adhesion molecules, which greatly enhance the infiltration and function of effector T cells. …”
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Hospitalised patients as stewards of their own antibiotic therapy: a qualitative analysis informing the strategic design of interventions to encourage shared decision-making in ter... by Guo, Huiling, Lye, David C., Ng, Tat Ming, Somani, Jyoti, Kwa, Andrea Lay Hoon, Chung, Jasmine Shimin, Chow, Angela

“…Highlighting potential side effects of antibiotics could motivate them to ask questions about their antibiotic therapies. …”
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Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases by Baek, Jong-Suep, Yeo, Eng Wan, Lee, Yin Hao, Tan, Nguan Soon, Loo, Say Chye Joachim

“…Therefore, this delivery system is a promising platform to control the delivery of NSAIDs to combat inflammatory diseases, thereby protecting against possible gastrointestinal side effects that may arise from the overuse of NSAIDs.…”
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Relative importance of soil properties and functional diversity to the spatial pattern of the forest soil nitrogen by Kang, Jian, Deng, Zebang, Zhang, Zhongrui, Chen, Shuilian, Huang, Jianguo, Ding, Xiaogang

“…However, few studies have investigated the factors influencing SN. The linear mixing effect and generalized additivity model were used to investigate the spatial patterns and influencing factors of SN by collecting and measuring the total nitrogen content of forest soil samples in the middle and lower reaches of the Xijiang River Basin (XRB). …”
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Clinical Cost-Effectiveness as a Novel Metric for Steering Emerging Medical Technology by Richards, Daniel Herndon

“…Results: The most sensitive driver of incremental effectiveness of LDD over surgery was, per the model, the potential of LDD to reduce systemic side effects. The potential clinical benefit of LDD over surgery was estimated, probabilistically, as between P10 and P90 values of 0.081 and 0.339 QALYs, respectively. …”
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Complex coacervates loaded with nano enzymes as microreactor by Ng, Si Yi

“…These nanoparticles are able to penetrate tissues and target specific cells due to their small size in nature and reduce potential side effects, improving the overall treatment efficacy. …”
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Diffuse Correlation Spectroscopy (DCS) and Diffuse Optical Spectroscopy (DOS) for photodynamic therapy monitoring. by Siti Raudhah Matyasir.

“…PDT is an emerging modality that has many advantages such as non-invasive, low side effects, low scarring, low risk of resistance, cost effective and shorter treatment time. …”
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Uptake and safety of Sotrovimab for prevention of severe COVID-19 in a cohort and self-controlled case series study by Patone, M, Snelling, AJ, Tibble, H, Coupland, C, Sheikh, A, Hippisley-Cox, J

“…Trials have shown it to have mild to moderate side effects, however, evidence regarding its safety in real-world settings remains insufficient. …”

Low-dose spironolactone and cardiovascular outcomes in moderate stage chronic kidney disease: a randomized controlled trial by Hobbs, FDR, McManus, RJ, Taylor, CJ, Jones, NR, Rahman, JK, Wolstenholme, J, Kim, S, Kwon, J, Jones, L, Hirst, JA, Yu, L-M, Mort, S

“…The most common reason for stopping spironolactone was a decrease in the estimated glomerular filtration rate that met prespecified stop criteria (n = 239, 35.4%), followed by participants being withdrawn due to treatment side effects (n = 128, 18.9%) and hyperkalemia (n = 54, 8.0%). …”

First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy by Hamdy, FC, Lamb, AD, Tullis, IDC, Verrill, C, Rombach, I, Rao, SR, Colling, R, Barber, PR, Volpi, D, Barbera-Martin, L, Lopez, JF, Omer, A, Hewitt, A, Lovell, S, Niederer, J, Lambert, A, Snoeck, J, Thomson, C, Leslie, T, Bryant, RJ, Mascioni, A, Jia, F, Torgov, M, Wilson, I, Gudas, J, Wu, AM, Olafsen, T, Vojnovic, B

“…Overall sensitivity and specificity in detecting non-lymph-node extra-prostatic cancer tissue were 100% and 65%, and 64% and 64% respectively for lymph node positivity. There were no side-effects associated with administration of the reagent. …”

Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice by Liang, Gengfan, Kow, Audrey Siew Foong, Lee, Yu-Zhao, Yusof, Rohana, Tham, Chau Ling, Ho, Yu-Chung, Lee, Ming Tatt

“…The current treatment for menopause-associated mood disorder provides only symptomatic relief and is associated with many side effects. Supplementation with vitamin E has been shown to be effective in ameliorating anxiety and depression. …”
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In vitro and in silico studies of Lawsone on inflammation-induced skin cells for development of skin anti-inflammatory treatment by Abdullah, Shazleen Sofea, Mohammad Latif, Muhammad Alif, Md Tohid, Siti Farah

“…Lawsone, an active phytoconstituent of Lawsonia inermis sp., is proposed as a safer alternative for the current skin anti-inflammatory treatments that are mainly steroidal with unwanted side effects which does not conform to the concept of halalan toyyiban in medicine. …”
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Exploring the therapeutic potential of 5-fluorouracil-loaded calcium carbonate nanoparticles combined with natural compound thymoquinone for colon cancer treatment by Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Abu Bakar, Md Zuki

“…Its favorable biocompatibility, pH sensitivity, and sustained release properties facilitated reduced toxic side effects of 5-FU on NIH3T3 normal cells and enhanced inhibitory effects on CT26 colon cancer cells. …”
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