Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma by Mizokami, Harue, Okabe, Atsushi, Choudhary, Ruchi, Mima, Masato, Saeda, Kenta, Fukuyo, Masaki, Rahmutulla, Bahityar, Seki, Motoaki, Goh, Boon-Cher, Kondo, Satoru, Dochi, Hirotomo, Moriyama-Kita, Makiko, Misawa, Kiyoshi, Hanazawa, Toyoyuki, Tan, Patrick, Yoshizaki, Tomokazu, Fullwood, Melissa Jane, Kaneda, Atsushi

“…Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignant epithelial tumor endemic to Southern China and Southeast Asia. While previous studies have revealed a low frequency of gene mutations in NPC, its epigenomic aberrations are not fully elucidated apart from DNA hypermethylation. …”
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Moris Mai : to be born by Cai, Yun, Har, Jiawei, Loh, Jing Ting, Toh, Yan Wei

“…Commonly known as East Timor, Timor-Leste achieved its independence in 2002, making it the youngest nation in Southeast Asia. Centuries of civil war hindered its social and economical development, with one of the imperative concerns being the high Child and Maternal Mortality Rates. …”
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A mixed methods study investigating factors affecting adherence to Plasmodium vivax malaria primaquine radical cure regimens among migrants along the Myanmar-Thailand border by Ansari, AT, Aung, KK, Win, HH, Beau, C, Nu, B, Soe, NL, Htoo, K, San, T, Wah, TG, Keereevijit, A, Phyo, AP, Chotivanich, K, White, NJ, Nosten, F, Hashmi, AH, Chu, CS

“…Background: The countries within the Greater Mekong Region of Southeast Asia have pledged to eliminate malaria by 2030. …”

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Glob... by Naghavi, M, Ong, KL, Aali, A, Almidani, O, Bandyopadhyay, S, Basnyat, B, Maude, R, Dolecek, C, Lacey, BWH

“…The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4–48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3–37·2] per 100 000 population). …”

Greater soil carbon losses from secondary than old-growth tropical forests by Raczka, Nanette Christine, Ho, Qian Yi, Srinivasan, Vupasana, Lee, Ming Yang, Ko, Chung-Wing, Königer, Madeleine, Chua, Terence, Binny, Delia, Ngo, Kang Min, Andersen, Kelly M.

“…The difference in soil C efflux between forest types indicates that with continued degradation of old-growth forests in Southeast Asia, conversion of old-growth forests into secondary forests may drive greater C loss from soils even after 70 years of regrowth.…”
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Are all renewable energy sources the same? a comparative analysis of public perceptions and preferences for renewable energy types in Southeast Asian cities by del Barrio Alvarez, Daniel, Wang, Nan, Sugiyama, Masahiro, Numata, Masako, Thuy, Truong Dang, Abd Aziz, Azlina, Palanca-Tan, Rosalina, Ze Ya, Aung, Yusuf, Ariel Anshory, Abd. Ghani, Awang Noor, Castillo, Gem, Siyaranamual, Martin Daniel

“…The realization of a sustainable energy transition in Southeast Asia will require the overcoming of the current high reliance on fossil fuels in the energy mix and the steady and rapid growth in energy demand in the region. …”
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Environmental calibration of coral luminescence as a proxy for terrigenous dissolved organic carbon concentration in tropical coastal oceans by Kaushal, Nikita, Tanzil, Jani T. I., Zhou, Yongli, Ong, Maria Rosabelle, Goodkin, Nathalie F., Martin, Patrick

“…Here, we use two replicate coral cores and concurrent in-situ biogeochemical data from the Sunda Shelf Sea in Southeast Asia, where peatlands supply high tDOM inputs, to show that variability in coral luminescence green-to-blue ratios (coral G/B) can be used to quantitatively reconstruct terrigenous dissolved organic carbon (tDOC) concentration. …”
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Development a novel paradigm for characterization of emerging contaminants in mixed-use anthropogenic impacted watersheds by Lee, Theodora Hui Yian

“…Emerging contaminants are found ubiquitously in all environmental matrices including surface water, groundwater and sediment, suggesting their propensity to be transported over large distances and persistent in the environment due to continuous input from anthropogenic sources. Moreover, Southeast Asia is a region especially vulnerable to emerging contaminant pollution given their high reliance on groundwater resources, rapid population growth, poor sanitation systems in peri-urban areas and agriculture expansion coupled with pesticide overuse. …”
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Current frailty knowledge, awareness, and practices among physicians following the 2022 European consensus document on Frailty in Cardiology by Wong, Jie Jun, Wang, Laureen Yi-Ting, Hasegawa, Koji, Ho, Kay Woon, Huang, Zijuan, Teo, Louis L. Y., Tan, Jack Wei Chieh, Kasahara, Kazuyuki, Tan, Ru-San, Ge, Junbo, Koh, Angela S.

“…Methods and results: We launched a prospective multinational web-based survey via social networks to broad cardiology communities representing multiple World Health Organization regions, including Western Pacific and Southeast Asia regions. Overall, 578 respondents [38.2% female; ages 35–49 years (55.2%) and 50–64 years (34.4%)] across subspecialties, including interventionists (43.3%), general cardiologists (30.6%), and heart failure specialists (HFSs) (10.9%), were surveyed. …”
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Early detection of reduced artemisinin susceptibility in plasmodium falciparum using novel phenotypic indicators by Xiong, Aoli

“…However, emerging artemisinin resistance in Southeast Asia is posing a real threat as it would have a significant impact on malaria control, treatment and the global elimination efforts. …”
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Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

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Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Feigin, VL, Abate, MD, Abate, YH, Bandyopadhyay, S, Bennett, DA, Lacey, B, Newton, CRJ

“…We found disparities in stroke burden and risk factors by GBD region, country or territory, and SDI, as well as a stagnation in the reduction of incidence from 2015 onwards, and even some increases in the stroke incidence, death, prevalence, and DALY rates in southeast Asia, east Asia, and Oceania, countries with lower SDI, and people younger than 70 years. …”

Fine-scale genetic structure and natural selection signatures of southwestern Hans inferred from patterns of genome-wide allele, haplotype, and haplogroup lineages by Wang, Mengge, Yuan, Didi, Zou, Xing, Wang, Zheng, Yeh, Hui-Yuan, Liu, Jing, Wei, Lan-Hai, Wang, Chuan-Chao, Zhu, Bofeng, Liu, Chao, He, Guanglin

“…Further three-way admixture models revealed larger genetic contributions from coastal southern East Asians into Guizhou Hans compared with the proposed inland ancient source from mainland Southeast Asia. We also identified candidate loci (e.g., MTUS2, NOTCH4, EDAR, ADH1B, and ABCG2) with strong natural selection signatures in Guizhou Hans via iHS, nSL, and ihh, which were associated with the susceptibility of the multiple complex diseases, morphology formation, alcohol and lipid metabolism. …”
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“一带一路”倡议对新加坡经济的动力及阻力 = Economic stimulus and impetus to Singapore caused by the “Belt and Road” initiative by 肖彬 Xiao, Bin

“…The “Belt” refers to the “Silk Road Economic Belt” which runs across the Eurasian continent, connecting Southeast Asia and Europe through the vast Central Asia. …”
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新加坡华人对中国的贡献 ：新加坡城市规划之父刘太格个案研究 = Contributions of Singaporean Chinese to China : a case study on Singapore’s father of city planning Liu Thai Ker... by 冯时辉 Phang, Shi Hwee

“…Despite being the last country in Southeast Asia to establish diplomatic relations with China, Singapore played an integral role in their modern development. …”
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A study of atmospheric gradient for the analysis of weather events and prediction of rainfall in the tropical region by Naha Biswas, Anik

“…The tropical region in southeast Asia has been mostly considered for conducting our study to explore the relation of the atmospheric gradient with rainfall for an area. …”
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A machine-learned approach for reducing airborne delays and environmental impact in terminal manoeuvring area using extended arrival management by Lim, Zhi Jun

“…The findings indicate that implementing an extended arrival manager in Singapore and Southeast Asia can effectively manage TMA congestion, reduce fuel consumption, and lower carbon dioxide emissions. …”
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