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341
Establishment and characterisation of CRTC1 knockout in rodent hippocampal neurons
Published 2017“…CRTC1 is a transcriptional modulator that is crucial for learning and memory. …”
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Final Year Project (FYP) -
342
Pulsed fiber laser at 1 μm wavelength region
Published 2017“…Thanks to its plentiful merits, such as high efficiency, vibration proof and maintenance free, high power Ytterbium-doped pulsed fiber lasers (YDPFLs) at 1 µm wavelength region have seen rapid development driven by the broad industrial applications over the past decades. …”
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Thesis -
343
A study on X chromosome reactivation using iXist
Published 2017“…Female mammals inactivate one of the two X chromosomes in each somatic cell in order to balance the X-linked gene dosage between females and males (X chromosome inactivation, XCI). …”
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Thesis -
344
Deployment and test of micro-grid power park - part I
Published 2018Get full text
Final Year Project (FYP) -
345
Evaluation of the synergistic effects of novel antimicrobial polymer 147-1
Published 2018“…There are many avenues which can be pursued, one of them is synergistic combination therapy. …”
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Final Year Project (FYP) -
346
Calcium-lead fluoro-vanadinite apatites. I. Disequilibrium structures
Published 2011“…The synthetic vanadinites (PbxCa10-x)(VO4)6F2δ, 1 < x < 9, adopt a P63/m apatite structure with 9.7590 (1) ≤ a ≤ 10.1179 (1) Å and 7.0434 (3) ≤ c ≤ 7.4021 (1) Å. …”
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Journal Article -
347
Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization
Published 2016“…Here we report a highly efficient method using butelase 1 to macrocyclize peptides and proteins ranging in sizes from 26 to >200 residues. …”
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Journal Article -
348
Kalman filtering with scheduled measurements - part I : estimation framework
Published 2013Get full text
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Conference Paper -
349
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350
Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome
Published 2010“…TMD and DS-AMKL almost always carry an acquired mutation in GATA1 resulting in exclusive synthesis of a truncated protein (GATA1s), suggesting that both trisomy 21 and GATA1 mutations are required for leukemogenesis. …”
Journal article -
351
Preclinical development of antisense conjugates for the treatment of myotonic dystrophy 1
Published 2024“…</p> <p>To address the challenge of CNS delivery in DM1, I also tested the potential of ASO conjugation to a CNS optimized, anti-transferrin receptor 1 (anti-TfR1)- targeting antibody. …”
Thesis -
352
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2
Published 2025“…Sphingosine-1-phosphate (S1P) is a signaling lysolipid critical to heart development, immunity, and hearing. …”
Journal article -
353
Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation
Published 2017Subjects:Thesis -
354
PIERCE1: a determinant of left-right asymmetry in mammals
Published 2019“…Transmission electron microscopy studies point towards a role for PIERCE1 in the assembly or trafficking of dynein arms and their components; however, protein interaction studies have proved inconclusive thus far at placing PIERCE1 within the network of known dynein arm assembly factors.…”
Thesis -
355
Within-host evolution of HIV-1 and the analysis of transmissible diversity
Published 2012“…I explain how the experimental data that I have generated and the analyses I have carried out address certain basic assumptions and predictions about HIV-1 transmission and may inform current strategies for vaccine design. …”
Thesis -
356
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357
One-Step Replica Symmetry Breaking of Random Regular NAE-SAT II
Published 2024“…Continuing our earlier work in Nam et al. (One-step replica symmetry breaking of random regular NAE-SAT I, <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://arxiv.org/abs/2011.14270">arXiv:2011.14270</jats:ext-link>, 2020), we study the random regular <jats:italic>k</jats:italic>-<jats:sc>nae-sat</jats:sc> model in the condensation regime. …”
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Article -
358
No One Wants To Be A Parasitologist: The Shrinking Field of America's Least Favorite Animals
Published 2024“…While parasites can cause horrible human suffering, especially in countries without reliable clean water or sanitation systems, only a fraction of parasites affect humans, with estimates as low as 0.1%. As climate change and habitat loss threaten animals, so too do they endanger the parasites that live on and inside them. …”
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Thesis -
359
Portia: It is Not a "Crisis Committee," But One Might Want a "Portia" Anyway
Published 2024Get full text
Article -
360