Simple Executive Function as an endophenotype of autism-ADHD, and differing associations between simple versus complex Executive Functions and autism/ADHD traits by Hendry, A, Bedford, R, Agyapong, M, Begum Ali, J, Bazelmans, T, Ersoy, M, Goodwin, A, Mason, L, Narvekar, N, Pasco, G, Johnson, MH, Jones, EJH, Charman, T

“…Exploratory analysis linked FH-autism specifically with lower Executive Attention (top-down attentional control) at age 2, and the combination of FH-autism and FH-ADHD with lower Complex EF (involving selectively deploying responses, or updating information) at age 3. …”

Maintaining energy provision in the heart: the creatine kinase system in ischaemia-reperfusion injury and chronic heart failure by Lygate, CA

“…We conclude that the correlative evidence linking impaired energetics to cardiac dysfunction is compelling; however, causal evidence from loss-of-function models remains equivocal. …”

Conceptualizing educational resilience during the COVID-19 pandemic by Aleghfeli, YK

“…The discussion rounds out the paper by linking international development agencies’ engagement of educational resilience to the academic discourse to emphasize the need for a more robust conceptualization of educational resilience that can address vulnerability to disruption risk.…”

Environmental health risks and well-being among the Orang Asli in Peninsular Malaysia: a review by Yew, Wong Chin

“…Water-borne infections and other infectious diseases have been epidemiologically linked to these environmental conditions. They are anecdotally high in remote indigenous communities. …”
Get full text

A technique for measuring the density and complexity of understorey vegetation in tropical forests by Marsden, Stuart J., Fielding, Alan H., Mead, Claire, Hussin, M.Zakaria

“…The dense understorey regrowth after disturbance of tropical forests has been linked to serious declines in many understorey and terrestrial animal taxa. …”
Get full text

Spatial distribution characteristics of leisure urban spaces and the correlation with population activity intensity: a case study of Nanjing, China by Li, Xinyang, Kozlowski, Marek, Ismail, Sumarni, Salih, Sarah Abdulkareem

“…The spatial distribution of Leisure Urban Spaces (LUSs) is closely linked to urban sustainability and residents’ quality of life. …”
Get full text

Development of a Highly Specific RecombinantToxocara canis Second-Stage Larva Excretory-Secretory Antigen for Immunodiagnosis of Human Toxocariasis by Yamasaki, Hiroshi, Araki, Kunioki, Lim, Patricia Kim Chooi, Zasmy, Ngah

“…The specificity of the recombinant Toxocara canis antigen developed for the immunodiagnosis of human toxocariasis was compared with that of the excretory-secretory antigen from T. canis second-stage larvae (TES) by enzyme-linked immunosorbent assay. A total of 153 human serum samples from patients infected with 20 different helminths, including 11 cases of toxocariasis, were examined. …”
Get full text

Effect of pH on phosphorylation of sago starch by Muhammad, K., Hussin, F., Man, Y.C., Ghazali, H.M.

“…Paste clarity measurements of the phosphorylated starches indicated that cross-linking accelerated rapidly above pH 8 with STMP, above pH 9 with STPP, and above pH 6 with a mixture of the two.…”
Get full text

Profiling the Malaysian Consumers’ Consumption Behaviour Toward Dietary Supplement Products (S/O: 13155) by Mohd Noor, Nor Azila, Liew, Kok-Hong, Yap, Sheau-Fen, Abdul Rahman, Maria, Muhammad, Azli

“…There exists compelling evidence linking nutrition deficiency with increased risk for chronic diseases. …”
Get full text

The Role of Emerging Technologies of Students' Academic Achievement at Politeknik Seberang Perai (PSP) by Omar, Nurul Ihsaniah, Ibrahim, Mohammad Noor

“…Factors like insufficient information, slow progress, and inadequate time management are linked to these failure rates. The study investigates the influence of new technologies on academic achievement at PSP using an ex post facto research strategy and quantitative methods to collect data from 200 respondents across various departments. …”
Get full text

Avoidance of Concave Obstacles Through Rotation of Nonlinear Dynamics by Huber, Lukas, Slotine, Jean-Jacques, Billard, Aude

“…Controlling complex tasks in robotic systems, such as circular motion for cleaning or following curvy lines, can be dealt with using nonlinear vector fields. …”
Get full text

Alternate Imaginaries for the Kinara: River Ravi’s Edge as a Threshold by Khalil, Mahwish

“…Finally, this thesis questions how the river's edge can be remapped to allow for the dismantling of top-down visions while addressing an urgency embodied within the shallow, receding flows of a polluted river, whose uncertain future remains contingent on distinct lines.…”
Get full text

Towards better urban intelligence: representation learning techniques for geospatial data analytics by Chen, Yile

“…They include points (e.g., points-of-interest), lines (e.g., road network), and polygons (e.g., geographical grids). …”
Get full text

Characterizing the interplay between super enhancers and chromatin interactions in cancer by Choudhary, Ruchi

“…Using HiChIP experiments in five human cell lines, we discovered multiple transcription factor (TF) clusters regulating chromatin interactions between SEs/enhancers and promoters, with one hub enriched in c-MYC and YY1. …”
Get full text

Investigating the human teashirt genes TSHZ2 and TSHZ3 in pancreatic and endocrine lineage commitment using genome modified human embryonic stem cells (hESC) by Eng, Shermaine Zi Hui

“…The CRISPR RNA-guided FokI-dCas9 nuclease (RFN) genome editing system was employed to create loss-of-function hESC lines. Two guide RNAs revealed successful editing in the 3’ end of TSHZ2 coding sequence while gRNAs tested for the 5’ end of TSHZ2 and for TSHZ3 were ineffective. …”
Get full text

Quantum dots-siRNA nanoplexes for gene silencing in central nervous system tumor cells by Lin, Guimiao, Chen, Ting, Zou, Jinyun, Wang, Yucheng, Wang, Xiaomei, Li, Jiefeng, Huang, Qijun, Fu, Zicai, Zhao, Yingying, Lin, Marie Chia-Mi, Xu, Gaixia, Yong, Ken-Tye

“…High gene transfection efficiency (>80%) was achieved on two glioblastoma cell lines, U87 and U251. The gene expression level (49.99 ± 10.23% for U87, 43.28 ± 9.66% for U251) and protein expression level (51.58 ± 7.88% for U87, 50.69 ± 7.59% for U251) of TERT is observed to decrease substantially after transfecting the tumor cells for 48 h. …”
Get full text
Get full text

Crystal structure of the FK506 binding domain of plasmodium falciparum FKBP35 in complex with FK506 by Kotaka, Masayo, Ye, Hong, Alag, Reema, Hu, Guangan, Bozdech, Zbynek, Preiser, Peter Rainer, Yoon, Ho Sup, Lescar, Julien

“…Compared to the human FKBP12−FK506 complex reported earlier, the structure reveals structural differences in the β5−β6 segment that lines the FK506 binding site. The presence in PfFKBD of Cys-106 and Ser-109 (substituting for His-87 and Ile-90, respectively, in human FKBP12), which are 4−5 Å from the nearest atom of the FK506 compound, suggests possible routes for the rational design of analogues of FK506 with specific antiparasitic activity. …”
Get full text
Get full text

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

“…We show here that colon cancer cell lines express also the paralog APC-like (APCL or APC2). …”
Get full text
Get full text

Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers by Erickson, A, Figiel, S, Rajakumar, T, Rao, S, Yin, W, Doultsinos, D, Magnussen, A, Singh, R, Poulose, N, Bryant, RJ, Cussenot, O, Hamdy, FC, Woodcock, D, Mills, IG, Lamb, AD

“…We first performed in-silico comparisons of inferred and directly resolved SNV and CNV status, from single cancer cells, from three different cell lines. We found that inferred SNV phylogenies accurately recapitulate DNA phylogenies (entanglement = 0.097). …”

Performance, heterosis and heritability in selected tropical maize single, double and three-way cross hybrids by Saleh, G.B., Abdullah, D., Anuar, A.R.

“…A series of tropical maize hybrids, involving 10 single, four double and four three-way crosses were evaluated with their parental inbred lines and three control varieties, at Universiti Putra Malaysia, Serdang, Malaysia, in a randomized complete block design, with three replications. …”
Get full text