Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762 by Chaidos, A, Caputo, V, Gouvedenou, K, Liu, B, Marigo, I, Chaudhry, M, Rotolo, A, Tough, DF, Smithers, NN, Bassil, AK, Chapman, TD, Harker, NR, Barbash, O, Tummino, P, Al-Mahdi, N, Haynes, AC, Cutler, L, Le, B, Rahemtulla, A, Roberts, I, Kleijnen, M, Witherington, J, Parr, NJ, Prinjha, RK, Karadimitris, A

“…In contrast, transcriptional upregulation of HEXIM1 is BRD2-4 independent. Finally, preclinical studies show that I-BET762 has a favorable pharmacologic profile as an oral agent and that it inhibits myeloma cell proliferation, resulting in survival advantage in a systemic myeloma xenograft model. …”

China : one year after September 11 by Tang, Shiping

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One-step disposable optical waveguide immunosensors by Zhou, Yan, Lam, Yee Loy

“…To develop one-step disposable optical waveguide immunosensors.…”
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Singapore One : multimedia broadband infrastructure for everyone by Tan, Chin Tuan.

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Free-standing one-dimensional plasmonic nanostructures by Jiang, Lin, Sun, Yinghui, Huo, Fengwei, Zhang, Hua, Qin, Lidong, Li, Shuzhou, Chen, Xiaodong

“…In this feature article, a category of chemically nanofabricated, unique free-standing one-dimensional (1D) plasmonic nanostructures has been summarized. …”
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Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya by Lugano, D, Kutima, B, Kimani, M, Sigilai, A, Gitonga, J, Karani, A, Akech, D, Karia, B, Ziraba, AK, Maina, A, Lambisia, A, Omuoyo, D, Mugo, D, Lucinde, R, Owuor, S, Konyino, G, Newman, J, Bailey, D, Nduati, E, Githinji, G, Agoti, CN, Bejon, P, Scott, JAG, Agweyu, A, Warimwe, GM

“…Our data show that antibodies from individuals in the general population in Kenya were less effective against the recent prevalent SARS-CoV-2 omicron variants (i.e. EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1) compared to the ancestral wildtype strain. …”

Temperature-dependent ultrafast carrier and phonon dynamics of topological insulator Bi1.5Sb0.5Te1.8Se1.2 by Cheng, Liang, La-o-vorakiat, Chan, Tang, Chi Sin, Nair, Saritha K., Xia, Bin, Wang, Lan, Zhu, Jian-Xin, Chia, Elbert E. M.

“…Using ultrafast optical pump-probe technique, we studied the temperature-dependent carrier and phonon dynamics of the topological insulator Bi1.5Sb0.5Te1.8Se1.2 single-crystal from 10 K to 300 K. …”
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Preparation of 1T′-phase ReS2xSe2(1‑x) (x = 0−1) nanodots for highly efficient electrocatalytic hydrogen evolution reaction by Lai, Zhuangchai, Chaturvedi, Apoorva, Wang, Yun, Tran, Thu Ha, Liu, Xiaozhi, Tan, Chaoliang, Luo, Zhimin, Chen, Bo, Huang, Ying, Nam, Gwang-Hyeon, Zhang, Zhicheng, Chen, Ye, Hu, Zhaoning, Li, Bing, Xi, Shibo, Zhang, Qinghua, Zong, Yun, Gu, Lin, Kloc, Christian, Du, Yonghua, Zhang, Hua

“…Here, by combining chemical vapor transport and Li-intercalation, we have prepared a series of 1T′-phase ReS2xSe2(1-x) (x = 0–1) nanodots to achieve high-performance HER in acid medium. …”
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The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells by Pillozzi, Serena, D'Amico, Massimo, Bartoli, Gianluca, Gasparoli, Luca, Petroni, Giulia, Crociani, Olivia, Marzo, Tiziano, Guerriero, Angela, Messori, Luigi, Severi, Mirko, Udisti, Roberto, Wulff, Heike, Chandy, Kanianthara George, Becchetti, Andrea, Arcangeli, Annarosa

“…The effect was maximal when KCa3.1 activation and Kv11.1 inhibition were combined. …”
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Development of applications for mobile devices I by Panganiban, Nicole Dale

“…Although such service was already available online, as the technology continues to progress developers looked into the ease of use of portable digital devices such as mobile phones. Smart phones became a necessity to most people. …”
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The role of free volume, hydrogen bonding, and crosslinks on physical aging in polymers of intrinsic microporosity (PIMs) by Joo, Taigyu, Rodriguez, Katherine Mizrahi, Lee, Hyunhee, Acharya, Durga, Doherty, Cara M., Smith, Zachary P.

“…The results suggest that higher initial fractional free volume is the primary factor contributing to higher rates of physical aging and that the introduction of hydrogen bonds and crosslinks reduces the initial free volume of PIM-1. …”
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Synthesis of a germylidenide anion from the C-C bond activation of a bis(germylene) by Seow, Celestine, Xi, Hong-Wei, Li, Yongxin, So, Cheuk-Wai

“…It was then reacted with 1 equiv of lithium in tetrahydrofuran (THF), which proceeded through the reduction of the imine skeleton, along with the C-C bond formation, to afford the bis(germylene) [2-(HC-NtBu)-6-(HC-NtBu)C6H3Ge:]2 (3). …”
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Pyridine N-oxide catalyzed living radical polymerization of methacrylates via halogen bonding catalysis by Xu, Haiyan, Wang, Chen-Gang, Lu, Yunpeng, Goto, Atsushi

“…The paper reports the generation of a carbon-center radical (R•) from an alkyl iodide (R-I) via a halogen bonding catalysis using pyridine N-oxide (PO) catalysts. …”
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Oxytocin receptor gene and parental bonding modulate prefrontal responses to cries : a NIRS study by Cataldo, Ilaria, Neoh, Michelle Jin-Yee, Chew, Wei Fang, Foo, Jia Nee, Lepri, Bruno, Esposito, Gianluca

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A study on protein secondary structure phase transition based on an effective hydrogen bonding potential by Leong, Hon Wai

“…Our results emphasize the role of hydrogen bonding network in polypeptide secondary structure phase transition. …”
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Green bonds : an introduction to a new market based approach in solving the regional haze crisis by Chew, John Han Hui, Chin, Yin Chai, Han, Kai Jie

“…Our paper explores the rationale for using Green Bonds over financial aid as well as explaining the details of the whole Green Bonds issuance process. …”
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Enlightening of the low-dimensional high-TC superconductivity: bond contraction and electron dual polarization [低维高温超导的启示: 键收缩与电子双重极化] by Sun, Chang Qing

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What makes an explosion happen? by Sun, Chang Q., Yao, Chuang, Zhang, Lei, Huang, Yongli

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Functional roles of transforming growth factor activated Kinase-1 (TAK1) in skin wound healing by Tan, Siew Hwey

“…We show here that during wound healing, TAK1 activates von Hippel-Lindau tumor suppressor (pVHL) expression in keratinocytes which, in turn, represses the expression of PDGF-B and, integrins beta1 and beta5 via inhibition of the Sp1-mediated transcription. …”
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Development of iBeacon application 3 by Choar, Choong Leong

“…This project mainly focuses on the development of the iBeacon, which is one of the components in IoT to create a more comprehensive automation system. …”
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