Synthesis resolution of 3,4,3'4'-tetramethoxyl-1,1'-1,2,3,4-tetrahydrobisisoquinoline and application in asymmetric alkylation reactions by Almeida Hazel Virgilia Ann

“…This report describes the synthesis of chiral 3,4,3',4'-tetramethoxyl-1,1'-1,2,3,4-tetrahydrobisisoquinoline. The compound is to be later used as a catalyst in the asymmetric alkylation addition reaction between 2-propargyl acetate and benzaldehyde to form an allylic alcohol. …”
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Effect of inflammation on apolipoprotein A-1(apoA-1) secretion by intestinal cells. by Yu, Kenneth.

“…In contrast, pro-inflammatory drugs such as lipopolysaccharides and endotoxin appeared to decrease intestinal secretion of apoA-1. These results indicate that aspirin and paracetamol, two of the most widely used medications for fevers and headaches, may have beneficial effects on the metabolism of high-density-lipoproteins(HDL),the so-called" good cholesterol" by increasing the rate of apoA-1 secretion by the intestine. …”
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Molecular study of Rasd1 transcriptional regulation and Rasd1-NonO interaction. by Ong, Angeline Shufen.

“…I also find that Dbp enhances Rasd1 promoter activity by binding to the CCAAT/enhancer binding protein beta (C/EBPβ) site located at the 5’ untranslated region (UTR) of Rasd1. …”
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The classification of 1D `perovskites' by Wong, Walter Pei De, Hanna, John V., Grimsdale, Andrew C.

“…The classification of perovskites has been unambiguous in the discussion of 3D and layered 2D perovskites due to the dimensional constraints. However, in 1D perovskites, the additional degrees of freedom have resulted in a large number of possible structural configurations. …”
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When I say … privilege by Cleland, Jennifer, Razack, Saleem

“…In the latest instalment of “When I Say…” Cleland and Razack argue it is time for medical education to acknowledge its complicit participation in socially constructed privilege and systemic inequalities and commit to change.…”
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Metaverse for virtual education 1 by Lau, Wynne Chen Yi

“…Several studies have indicated that the use of higher quality VR equipment provides a more immersive experience for its users, however, not all education institutes have the budget to invest in the more expensive and higher quality VR equipment for every one of their students. Hence, this project focuses on the development of a metaverse prototype for applications in virtual education to help educational institutes manage the use of the limited amount of VR equipment. …”
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Tangible Video Communication 1 by Yang, Fan

“…The key parts in the development phase are (1) establishing a network connection and (2) generating an efficient haptic rendering algorithm. (1) is used to solve the task of data transmission, while (2) is used to compute feedback force applied to haptic devices. …”
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Visualising mathematics for little ones by Tho, Shi Yee

“…This project is an exploration on children’s interests towards mathematics as a subject. I used to fair badly in mathematics until I received help from a tutor who made sure I fully understood the basic concepts. …”
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EV Myvi emo-1 by Ridzuan, Lizam

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In-situ chemical attenuation of pharmaceutically active compounds using CaO₂: influencing factors, mechanistic modeling, and cooperative inactivation of water-borne microbial pathogens by Zheng, Ming, Gao, Bing, Zhang, Jie, El-Din, Mohamed Gamal, Snyder, Shane Allen, Wu, Minghong, Tang, Liang

“…In addition, CaO2 at 0.01-0.1 g L-1 can be applied in remediation of SW contaminated by PhACs and pathogenic bacteria, which can degrade target PhACs with efficiencies of 21-100% under 0.01 g L-1 CaO2, and inactivate 100% of test bacteria under 0.1 g L-1 CaO2. …”
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Mosquito-borne diseases in urban East African Community region: a scoping review of urban typology research and mosquito genera overlap, 2000-2024 by Joseph, NK, Mumo, E, Morlighem, C, Macharia, PM, Snow, RW, Linard, C

“…Background: Growing concerns about mosquito-borne diseases (MBDs) in urban settings have prompted renewed urgency for collaborative and active mosquito surveillance programs. …”

Antibacterial effect of ethanolic Gnetum gnemon L. leaf extract on food-borne pathogens and its application as a natural preservative on raw quail eggs by Trisha, Mansura Rahman, Deavyndra Gunawan, Vyenna, Wong, Jun Xian, Pak Dek, Mohd Sabri, Rukayadi, Yaya

“…EGLE may be a viable alternative to synthetic preservatives in combating food-borne pathogens. © 2024 The Authors…”
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Investigating ERO1α, IDO1 and MHC Class I : potential proteins that can be manipulated to change the tumour microenvironment from ‘cold’ to ‘hot’ by Peck, Jia Yi

“…ERO1α, a cancer-associated protein, and IDO1, an immunomodulatory enzyme, have been shown to be associated with the expression of MHC Class I proteins. …”
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Structural characterization of vaccinia-related kinase 1 (VRK1), a histone mitotic kinase by Ngow, Yeen Shian

“…To-date, the structural basis of VRK1-ATP interaction is not available, hindering the progress toward designing VRK1 specific Type I inhibitors. …”
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Novel modulo multipliers for moduli 2^n-1, 2^n and 2^n+1. by Ramya Muralidharan

“…In this thesis, special modulo 2^n-1, modulo 2^n and modulo 2^n+1 multipliers are studied. …”
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Topological phase transition in quasi-one-dimensional bismuth iodide Bi 4 I 4 by Zhao, WX, Yang, M, Du, X, Li, YD, Zhai, KY, Hu, YQ, Han, JF, Huang, Y, Liu, ZK, Yao, YG, Zhuang, JC, Du, Y, Zhou, JJ, Chen, YL, Yang, LX

“…Quasi-one-dimensional (quasi-1D) bismuth iodide Bi4I4 exhibits versatile topological phases of matter including weak topological insulator (WTI) and higher-order topological insulator (HOTI) phases with high tunability in response to external parameters. …”

Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I by Liu, X, Zhang, Z, Aguirre, T, Shipton, ML, Fu, L, Du, J, Furkert, D, Qi, J, Chin, AC, Riley, AM, Liu, T, Zhang, X, Potter, BVL, Fiedler, D, Zhu, Y, Fu, C

“…Depleting 5PP-InsP₅ by deleting IP6K1 or blocking IP6K1 activity disrupts the interaction between UBE4A and apoA-I, preventing apoA-I degradation, leading to increased production of apoA-I. …”

Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762 by Chaidos, A, Caputo, V, Gouvedenou, K, Liu, B, Marigo, I, Chaudhry, M, Rotolo, A, Tough, DF, Smithers, NN, Bassil, AK, Chapman, TD, Harker, NR, Barbash, O, Tummino, P, Al-Mahdi, N, Haynes, AC, Cutler, L, Le, B, Rahemtulla, A, Roberts, I, Kleijnen, M, Witherington, J, Parr, NJ, Prinjha, RK, Karadimitris, A

“…In contrast, transcriptional upregulation of HEXIM1 is BRD2-4 independent. Finally, preclinical studies show that I-BET762 has a favorable pharmacologic profile as an oral agent and that it inhibits myeloma cell proliferation, resulting in survival advantage in a systemic myeloma xenograft model. …”

China : one year after September 11 by Tang, Shiping

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One-step disposable optical waveguide immunosensors by Zhou, Yan, Lam, Yee Loy

“…To develop one-step disposable optical waveguide immunosensors.…”
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