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Cell activation-based screening of natively paired human T cell receptor repertoires
Published 2025“…Adoptive immune therapies based on the transfer of antigen-specific T cells have been used successfully to treat various cancers and viral infections, but improved techniques are needed to identify optimally protective human T cell receptors (TCRs). …”
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22
The role of ADAM10 and mucin-like molecules in modulating cell-cell interactions
Published 2023“…To preserve the non-inflammatory nature of apoptotic cell death, a rapid removal of apoptotic cells, known as efferocytosis, is required to maintain tissue homeostasis. …”
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23
Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors
Published 2023“…Understanding how cellular decisions by receptor/ligand interactions at cell/cell interface has been challenging because it is difficult to independently vary the surface density of multiple ligands. …”
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24
Fast Charging of Lithium-Ion Batteries While Accounting for Degradation and Cell-to-Cell Variability
Published 2024“…This study explores a strategy for the design of fast charging protocols that takes into account the influence of the variability between battery cells on factors that can impact degradation. We employ a non-intrusive polynomial chaos expansion to identify the key parameters for each degradation condition. …”
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25
The effect of secreted factors from breast tumour cells on osteogenic potential of mesenchymal cells
Published 2015“…Cancer is a disease caused by uncontrolled division of cells. These cells can invade nearby tissues and spread to the other parts of the body through the blood and lymph systems. …”
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Final Year Project (FYP) -
26
Single cell analysis at the nanoscale
Published 2013“…In this tutorial review, we survey recent progress toward single cell analysis at the nanoscale by emphasizing how the advancement in nanotechnology has brought a plethora of nanotools to interrogate single cells with high spatiotemporal resolutions. …”
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Journal Article -
27
Parameter extraction of solar cells
Published 2015“…Its bandgap is too low to be the best solar cell and also silicon is an indirect material which has low absorption co-efficient. …”
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Final Year Project (FYP) -
28
Vibrational signatures of living cells
Published 2024“…Taking a reductionist perspective of cellular mechanobiology to its extreme, a living single cell functions like a mechanical machine: an intricate assembly of micromolecular structural parts, moving parts, and actuators that function together. …”
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Characterising the iron dependence of T-cells
Published 2023“…Iron is an essential micronutrient which interacts with ~400 different protein types in human cells. Meanwhile, iron deficiency remains globally prevalent affecting >1.2 billion people. …”
Thesis -
30
Soft cells and the geometry of seashells
Published 2024“…Remarkably, these ideal soft shapes, born out of geometry, are found abundantly in nature, from cells to shells.…”
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31
Transcription factors interact with RNA to regulate genes
Published 2023Subjects: “…Cell Biology…”
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32
Long-Term Tracking Mesenchymal Stem Cell Differentiation with Photostable Fluorescent Nanoparticles
Published 2017Subjects: “…Mesenchymal stem cell…”
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Journal Article -
33
Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis
Published 2017Subjects: “…Neural stem cells…”
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Journal Article -
34
Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells
Published 2024“…Here, using an in vitro NK cell killing system, we show that non‐cell‐autonomous mechanisms in aneuploid cells predominantly mediate their clearance by NK cells. …”
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35
Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing
Published 2023“…To circumvent these challenges, bioinspired cell-derived nanovesicles (CDNs) that mimic EVs were obtained by shearing mesenchymal stem cells (MSCs) through membranes with different pore sizes. …”
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Journal Article -
36
Multi-omics analysis and modelling of T cell immunity and interferon signalling pathways for engineered T cell therapy
Published 2022“…Cell type annotation methods are evaluated for their ability to identify closely-related T cell populations in single-cell RNA sequencing (scRNA-seq) data. …”
Thesis -
37
Dual role of mesenchymal stem/stromal cells and their cell‐free extracellular vesicles in colorectal cancer
Published 2024“…The beneficial properties of stem cells are attributed to their cell–cell interactions as well as the secretion of paracrine factors in the tissue microenvironment. …”
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Low-cost incubator for live-cell imaging
Published 2024Subjects: Get full text
Final Year Project (FYP) -
40
Human Wharton's jelly mesenchymal stem cells show unique gene expression compared with bone marrow mesenchymal stem cells using single-cell RNA-sequencing
Published 2021Subjects: Get full text
Journal Article