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341
Computational investigations of HIV-1 protease and protease inhibitors interactions
Published 2014“…Both wild type HIV-1 proteases and mutated HIV-1 proteases were used in the docking simulations. …”
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Final Year Project (FYP) -
342
Timelapse++ Application 1 : controlling the camera and motorised sliding kit
Published 2016“…Abstract Time-lapse is a photography technique that shoots frames of one scene at a certain interval and records the changing of the scene over the time. …”
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Final Year Project (FYP) -
343
Design of 1.8V supply subthreshold voltage reference
Published 2016“…Nonetheless, the process used in this design is Austria Micro System 0.18μm CMOS with 1.8V supply. Hence the headroom of device operation is limited due to low supply voltage. …”
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Final Year Project (FYP) -
344
1,3,2-diazaphospholene-catalysed reduction of unsaturated bonds
Published 2016“…This thesis mainly focuses on the novel usage of 1,3,2-diazaphospholene as an efficient catalyst in various reduction reactions including transfer hydrogenation of azo compounds (N=N), hydroboration of carbonyl compounds (C=O) as well as N-formylation of amines using CO2. …”
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Thesis -
345
Establishment and characterisation of CRTC1 knockout in rodent hippocampal neurons
Published 2017“…CRTC1 is a transcriptional modulator that is crucial for learning and memory. …”
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Final Year Project (FYP) -
346
Pulsed fiber laser at 1 μm wavelength region
Published 2017“…Thanks to its plentiful merits, such as high efficiency, vibration proof and maintenance free, high power Ytterbium-doped pulsed fiber lasers (YDPFLs) at 1 µm wavelength region have seen rapid development driven by the broad industrial applications over the past decades. …”
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Thesis -
347
A study on X chromosome reactivation using iXist
Published 2017“…Female mammals inactivate one of the two X chromosomes in each somatic cell in order to balance the X-linked gene dosage between females and males (X chromosome inactivation, XCI). …”
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Thesis -
348
Deployment and test of micro-grid power park - part I
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Final Year Project (FYP) -
349
Evaluation of the synergistic effects of novel antimicrobial polymer 147-1
Published 2018“…There are many avenues which can be pursued, one of them is synergistic combination therapy. …”
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Final Year Project (FYP) -
350
Calcium-lead fluoro-vanadinite apatites. I. Disequilibrium structures
Published 2011“…The synthetic vanadinites (PbxCa10-x)(VO4)6F2δ, 1 < x < 9, adopt a P63/m apatite structure with 9.7590 (1) ≤ a ≤ 10.1179 (1) Å and 7.0434 (3) ≤ c ≤ 7.4021 (1) Å. …”
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Journal Article -
351
Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization
Published 2016“…Here we report a highly efficient method using butelase 1 to macrocyclize peptides and proteins ranging in sizes from 26 to >200 residues. …”
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Journal Article -
352
Kalman filtering with scheduled measurements - part I : estimation framework
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Conference Paper -
353
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354
Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome
Published 2010“…TMD and DS-AMKL almost always carry an acquired mutation in GATA1 resulting in exclusive synthesis of a truncated protein (GATA1s), suggesting that both trisomy 21 and GATA1 mutations are required for leukemogenesis. …”
Journal article -
355
Preclinical development of antisense conjugates for the treatment of myotonic dystrophy 1
Published 2024“…</p> <p>To address the challenge of CNS delivery in DM1, I also tested the potential of ASO conjugation to a CNS optimized, anti-transferrin receptor 1 (anti-TfR1)- targeting antibody. …”
Thesis -
356
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2
Published 2025“…Sphingosine-1-phosphate (S1P) is a signaling lysolipid critical to heart development, immunity, and hearing. …”
Journal article -
357
Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation
Published 2017Subjects:Thesis -
358
PIERCE1: a determinant of left-right asymmetry in mammals
Published 2019“…Transmission electron microscopy studies point towards a role for PIERCE1 in the assembly or trafficking of dynein arms and their components; however, protein interaction studies have proved inconclusive thus far at placing PIERCE1 within the network of known dynein arm assembly factors.…”
Thesis -
359
Within-host evolution of HIV-1 and the analysis of transmissible diversity
Published 2012“…I explain how the experimental data that I have generated and the analyses I have carried out address certain basic assumptions and predictions about HIV-1 transmission and may inform current strategies for vaccine design. …”
Thesis -
360