Detection of florfenicol resistance in opportunistic Acinetobacter spp. infections in rural Thailand by Tan, Bernice Siu Yan, Mohan, Lalit, Watthanaworawit, Wanitda, Ngamprasertchai, Thundon, Nosten, Francois H., Ling, Clare, Bifani, Pablo

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The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

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New multi-target based therapeutics against an opportunistic superbug by Premkumar, Jayaraman.

“…These combinations based searches aided in identifying novel synergistic phytochemical-antibiotic combinations, an alternate therapeutic option for the treatment of Pseudomonas infections. The second part of the project involved hypothesis driven multi-target drug design against P. aeruginosa and computational evaluation of the designed hybrid compounds using various computer-aided drug design methodologies combining homology modelling, physico-chemical, stereo-electronic properties predictions, molecular docking and dynamics simulations. …”
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Structural study of ribosome : 1) structural basis of EF-G in translocation. 2) molecular mechanism of ribosome-dependent toxin YoeB in mRNA cleavage by Chen, Yun

“…This process, known as translocation, is the most conserved part between prokaryotic and eukaryotic translation. …”
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Surface plasmon resonance (SPR) enhanced biosensors by Zhang, Jinling

“…The sensing principle in most of my works are SPR and SPR enhanced fluorescence. In the first part of my work, I designed two kinds of Au nanohole array, with (PAuNH array) and without (AuNH array) photoresist between the Au layer and the glass slides for the purpose of fluorescent enhancement using a model dye Alexa 647. …”
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Numerical and experimental investigation of thick composites manufacturing for wind turbines by Ammasai Sengodan, Ganapathi

“…In addition, it is used to monitor the resin pressure distribution of a curing laminate which is the key parameter that controls the strength, stiffness and nucleation of voids in the cured part. Finally, the application of the currently developed numerical procedure was demonstrated using two case studies. …”
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Two-dimensional transitional metal dichalcongenide heterostructures : interface optical properties by Zheng, ShouJun

“…In the monolayer heterojunction, the photoluminescence peak shifts continuously from 686.8 nm at triangle center to 633.4 nm at the edge at excitation wavelength of 457 nm. The part of WxMo1-xS2 is attested to be composition-graded alloy according to the position dependent PL peaks and we also calculated the composition of this alloy. …”
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Structural and functional studies of C-nucleoside formation enzymes by Li, W

“…</p> <br> <p>The thesis builds towards the study the enzyme mechanism using X-ray Free Electron Laser (XFEL). A critical part of this work is the development of photo-activated cage substrates, these will allow synchronization of the catalytic mechanisms. …”

The effects of exercise, heat-induced hypo-hydration and rehydration on blood–brain-barrier permeability, corticospinal and peripheral excitability by Uddin, N, Scott, J, Nixon, J, Patterson, SD, Kidgell, D, Pearce, AJ, Waldron, M, Tallent, J

“…Methods: To assess this, 12 participants took part in a randomised crossover study, in a prolonged (3 h) submaximal (60 W) cycling protocol under 3 conditions: (i) in 45 °C (achieving ~ 5% body mass reduction), with post-exercise rehydration in 2 h (RHY2), (ii) with rehydration across 24 h (RHY24), and (iii) a euhydrated trial in 25 °C (CON). …”

A preliminary study on the effects of substituting fishmeal with defatted black soldier fly (Hermetia illucens) larval meal on Asian seabass (Lates calcarifer) juveniles: Growth pe... by Liu, Yun, Andin, Victor Charlie, Chor, Wei-Kang, Gunasekaran, Baskaran, Chong, Chou-Min, Lee, Po-Tsang, Loh, Jiun-Yan

“…This study aims to develop an alternative aquafeed derived from insect meal for Lates calcarifer juveniles, with the objectives of exploring the physiological performance, biological parameters, and economic analysis of substituting fishmeal (FM) with defatted black soldier fly (Hermetia illucens) larvae (BSFL) as part of the diet of L. calcarifer juveniles. Five practical diets were formulated to include 0% (BSFL0, serves as control group), 5% (BSFL5), 10% (BSFL10), 15% (BSFL15), and 20% (BSFL20) of BSFL meal, partially or fully replacing FM, respectively. …”

Design and Implementation of Active Antennas for IoT-Based Healthcare Monitoring System by MUSA, UMAR, MOHD SHAH, SHAHARIL, A. MAJID, HUDA, AHMAD MAHADI, ISMAIL, A. RAHIM, MOHAMAD KAMAL, YAHYA, MUHAMMAD SANI, ZAINAL ABIDIN, ZUHAIRIAH

“…This work presents the design and implementation of active antennas as a part of a healthcare monitoring system that is based on the Internet of Things (IoT). …”
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Design and Implementation of Active Antennas for IoT-Based Healthcare Monitoring System by MUSA, UMAR, MOHD SHAH, SHAHARIL, A. MAJID, HUDA, MAHADI, ISMAIL AHMAD, A. RAHIM, MOHAMAD KAMAL, YAHYA, MUHAMMAD SANI, ZAINAL ABIDIN, ZUHAIRIAH

“…This work presents the design and implementation of active antennas as a part of a healthcare monitoring system that is based on the Internet of Things (IoT). …”
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Interventions for improving patients’ trust in doctors and groups of doctors by Rolfe, Alix, Cash-Gibson, Lucinda, Car, Josip, Sheikh, Aziz, McKinstry, Brian

“…Authors' conclusions: Overall, there remains insufficient evidence to conclude that any intervention may increase or decrease trust in doctors. This may be due in part to the sensitivity of trust instruments, and a ceiling effect, as trust in doctors is generally high. …”
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Sociospatial reframing of walking through inclusive streets and urban heritage by Wang, Yongcheng

“…The semi-structured interviews unveiled a wide range of sociospatial themes, including movement within an extended pedestrian network, such as detouring and taking shortcuts, and ambivalence about space sharing that is in part caused by both the complications of rights-of-way among active transport modes and preconceptions of social norms in a local-foreign divide. …”
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Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

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The avocado genome informs deep angiosperm phylogeny, highlights introgressive hybridization, and reveals pathogen-influenced gene space adaptation by Rendón-Anaya, Martha, Ibarra-Laclette, Enrique, Méndez-Bravo, Alfonso, Lan, Tianying, Zheng, Chunfang, Carretero-Paulet, Lorenzo, Perez-Torres, Claudia Anahí, Chacón-López, Alejandra, Hernandez-Guzmán, Gustavo, Chang, Tien-Hao, Farr, Kimberly M, Barbazuk, W Brad, Chamala, Srikar, Mutwil, Marek, Shivhare, Devendra, Alvarez-Ponce, David, Mitter, Neena, Hayward, Alice, Fletcher, Stephen, Rozas, Julio, Sánchez Gracia, Alejandro, Kuhn, David, Barrientos-Priego, Alejandro F, Salojärvi, Jarkko, Librado, Pablo, Sankoff, David, Herrera-Estrella, Alfredo, Albert, Victor A, Herrera-Estrella, Luis

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The MALINA oceanographic expedition : how do changes in ice cover, permafrost and UV radiation impact biodiversity and biogeochemical fluxes in the Arctic Ocean? by Massicotte, P., Amon, R. M. W., Antoine, D., Archambault, P., Balzano, S., Bélanger, S., Benner, R., Boeuf, D., Bricaud, A., Bruyant, F., Chaillou, G., Chami, M., Charrière, B., Chen, J., Claustre, H., Coupel, P., Delsaut, N., Doxaran, D., Ehn, J., Fichot, C., Forget, M. H., Fu, P., Gagnon, J., Garcia, N., Gasser, B., Ghiglione, J. F., Gorsky, G., Gosselin, M., Gourvil, P., Gratton, Y., Guillot, P., Heipieper, H. J., Heussner, S., Hooker, S. B., Huot, Y., Jeanthon, C., Jeffrey, W., Joux, F., Kawamura, K., Lansard, B., Leymarie, E., Link, H., Lovejoy, C., Marec, C., Marie, D., Martin, J., Martín, J., Massé, G., Matsuoka, A., McKague, V., Mignot, A., Miller, W. L., Miquel, J. C., Mucc,i A., Ono, K., Ortega-Retuerta, E., Panagiotopoulos, C., Papakyriakou, T., Picheral, M., Prieu,r L., Raimbault, P., Ras, J., Reynolds, R. A., Rochon, A., Rontani, J. F., Schmechtig, C., Schmidt, S., Sempéré, R., Shen, Y., Song, G., Stramski, D., Tachibana, E., Thirouard, A., Tolosa, I., Tremblay, J. E., Vaïtilingom, M., Vaulot, Daniel, Vaultier, F., Volkman, J. K., Xie, H., Zheng, G., Babin, M.

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Filamentous oligomer structure reconstruction and a new filament picking method for Cryo-EM micrographs by Xu, Chenrui

“…NLRP1 and CARD8 are two similar innate immune receptors that undergo auto-proteolytic activation, when encountering the right triggering signals from cellular damage or pathogen infection, and release a filament-forming CARD domains. Here, as part of my Ph.D. research, I present structures of NLRC4-CARD, NLRP1-CARD, and CARD8-CARD filaments, at approximately 3.7 Å resolution. …”
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Endothelial damage arising from high salt hypertension is elucidated by vascular bed systematic profiling by Vinaiphat, Arada, Pazhanchamy, Kalailingam, JebaMercy, Gnanasekaran, Ngan, SoFong Cam, Leow, Melvin Khee-Shing, Ho, Hee Hwa, Gao, Yong-Gui, Lim, Kah-Leong, Richards, A. Mark, de Kleijn, Dominique P. V., Chen, Christopher P., Kalaria, Raj N., Liu, Jian, O'Leary, Deborah D., McCarthy, Neil E., Sze, Siu Kwan

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Biomimetic whisker transducer for vibrissal tactile sensing by Ju, Feng

“…And the damping property of the surface can be obtained from real part of WT-measured mechanical impedance. The WT was also used to study the mechanism of rat’s vibrissal tactile texture perception in a biomimetic perspective. …”
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