Showing 1,081 - 1,100 results of 6,921 for search '((((aina OR bina) OR (ping OR ming)) OR (fine OR find)) OR ((anna OR (spinga OR spingat)) OR pin))', query time: 0.22s Refine Results
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    Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Aβ plaques in mouse and human brains by Huang, Helen Xuexia, Inglese, Paolo, Tang, Jiabin, Yagoubi, Riad, Correia, Gonçalo D. S., Horneffer-van der Sluis, Verena M., Camuzeaux, Stephane, Wu, Vincen, Kopanitsa, Maksym V., Willumsen, Nanet, Jackson, Johanna S., Barron, Anna M., Saito, Takashi, Saido, Takaomi C., Gentlemen, Steve, Takats, Zoltan, Matthews, Paul M.

    Published 2024
    “…Likewise, in human donors with varying Braak stages, similar studies of cortical sections revealed co-expression of lysophospholipids and ceramides around Aβ plaques in AD (Braak stage V/VI) but not in earlier Braak stage controls. Our findings in mice provide evidence of temporally and spatially heterogeneous differences in lipid composition as local and global Aβ-related pathologies evolve. …”
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    Journal Article
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    Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice by Mohd Kasim, Vivi Nur Khalieda, Lee, Yu Zhao, Bakrin, Ikmal Hisyam, Hussain, Mohd Khairi, Israf, Daud Ahmad, Shaari, Khozirah, Tan, Ji Wei, Lee, Ming Tatt, Tham, Chau Ling

    Published 2024
    “…There was a minor discrepancy between the two routes of administration, with orally treated tHGA showing significant reductions in Scoring of Atopic Dermatitis (SCORAD), tissue eosinophil infiltration, serum IgE and skin IL-4 levels with treatment of 40 and 80 mg/kg tHGA, whereas topically applied tHGA showed significant reductions in all dosages. These findings suggest that tHGA exhibited therapeutic potential for AD as both oral and topical treatment ameliorates AD-like symptoms in the murine model. © The Author(s) 2024.…”
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    Article