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Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction
Published 2023“…Several patient-derived models have been established lately for the prediction of drug response. However, each of these models has its limitations that impede their clinical application. …”
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Journal Article -
43
Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Thesis -
44
Janus particle preparation through UV-induced partial photodegradation of spin-coated particle films
Published 2022“…Photocatalytic titanium dioxide particles prefunctionalized with a surface coating were assembled as particle films via spin-coating on a substrate. The particle films were placed directly under an ultraviolet light source, which induced the photodegradation of the surface coating only on the particle surfaces exposed to the light. …”
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Journal Article -
45
Spatially controlled molecular encapsulation in natural pine pollen microcapsules
Published 2020Get full text
Journal Article -
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”
Thesis -
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
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Thesis -
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RES.10-001 Making Science and Engineering Pictures, Fall 2014
Published 2017Get full text
Learning Object -
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AI is a viable alternative to high throughput screening: a 318-target study
Published 2024Get full text
Journal Article -
53
Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens
Published 2024“…To fill the existing gap in drug dose personalization and simplification of complex medication regimens commonly encountered in the treatment of cardiovascular disease, tuberculosis, and tapering of corticosteroid therapy, a modular titratable polypill approach that simultaneously addresses both aspects is proposed. …”
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Article -
54
Ellipsometry studies on anodic aluminium oxide (AAO)growth mechanism on high purity aluminium plate
Published 2014“…In the biomedical field, AAO was used many applications such as pathogens microfiltration, biomolecules quantification, drug delivery etc, However, it had been a challenge to produce the necessary microstructure for all the mentioned applications. …”
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Final Year Project (FYP) -
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Sustained delivery of timolol maleate from liposomal nanocarriers
Published 2014“…Liposomes were prepared using thin film hydration and average particle size in the range of around 100 nm was prepared using a bench top extruder and drug was actively loaded by ammonium sulphate gradient loading technique. …”
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Final Year Project (FYP) -
56
Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials
Published 2008“…We intend to fill this gap by interrogating the biophysical events involved in membrane-polymer interaction, biological adhesion, tissue engineering and cellular fluid mechanics. …”
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Research Report -
57
Antimicrobial efficacy testing of antibiotic-containing biodegradable nanopolymers against biofilm and planktonic cells.
Published 2009“…With efficient use of drug-encapsulated nanopolymers, bactericidal dosages are sufficiently lowered and dosing intervals can be extended due to the sustained drug release feature afforded by these efficacious nanocarriers.…”
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Final Year Project (FYP) -
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Factors affecting trans-scleral transport of poly (butadiene-b-ethylene oxide) polymersomes
Published 2020“…In this light, this research work examines the suitability of polymersomes for ocular drug delivery via periocular route of drug administration. …”
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Thesis-Master by Research -
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A biodegradable ocular implant for long-term suppression of intraocular pressure
Published 2016“…However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage, and lack of patient compliance. Suboptimal control of the IOP leads to disease progression and eventually to blindness. …”
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Journal Article -
60
Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study...
Published 2024“…S Typhi genotype 4.3.1 (H58) was common in all sites, but with different dominant variants (4.3.1.1.EA1 in Blantyre, 4.3.1.1 in Dhaka, and 4.3.1.2 in Kathmandu). …”
Journal article