Gaps In Primary Care And Health System Performance In Six Latin American And Caribbean Countries by Macinko, James, Guanais, Frederico C., Mullachery, Pricila, Jimenez, Geronimo

Subjects: “…Organization and Delivery of Care…”
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Flood inundation mapping in the Kelantan River Basin, Malaysia, using Sentinel-1 SAR and Google Earth Engine by Yi, Lin Tew, Mou, Leong Tan, Liew, Juneng, Sazali Osman, Mohamad Hafiz Hassan, Narimah Samat, Chun, Kiat Chang, Li, Longhui

“…In this study, GEE was utilized to generate flood inundation maps for the Kelantan River Basin (KRB) using Sentinel-1 SAR data. Site inspections and Sentinel-2 Multispectral Instrument (MSI) satellite images of the actual flood regions were then used to validate the flood inundation maps. …”
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Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations by Bi, Jialin, Wee, JunJie, Liu, Xiang, Qu, Cunquan, Wang, Guanghui, Xia, Kelin

“…Biologically, protein-protein interactions between SARS-CoV-2 surface spike (S) protein and human ACE2 protein are the key mechanism behind the COVID-19 disease. …”
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Characterising the T cell responses to SARS-CoV-2 including variants of concern induced by natural infection and vaccines by Adele, S

“…<p>The COVID-19 pandemic, caused by SARS-CoV-2, has profoundly impacted global health, prompting extensive research into vaccine responses and the immune dynamics of SARS-CoV2 variants of concern (VOCs). …”

Detecting changes in population trends in infection surveillance using community SARS-CoV-2 prevalence as an exemplar by Pritchard, E, Vihta, K-D, Eyre, DW, Hopkins, S, Peto, TEA, Matthews, PC, Stoesser, N, Studley, R, Rourke, E, Diamond, I, Pouwels, KB, Walker, AS, COVID-19 Infection Survey Team

“…Substantial changes in SARS-CoV-2 prevalence with emergence of variants provides opportunity to investigate different methods to do this. …”

A systems biology approach to define SARS-CoV-2 correlates of protection in non-human primates by Brady, C

“…SARS-CoV-2 is expected to become a seasonal human coronavirus, with annual vaccination advised for vulnerable populations, similar to influenza. …”

Chronic neuropsychiatric sequelae of SARS-CoV-2: protocol and methods from the Alzheimer's Association Global Consortium by de Erausquin, GA, Snyder, H, Brugha, TS, Newton, C

“…No available evidence supports the notion that cognitive impairment after SARS-CoV-2 infection is a form of dementia (ADRD or otherwise). …”

First nosocomial cluster of COVID-19 due to the Delta variant in a major acute care hospital in Singapore: investigations and outbreak response by Lim, Wei Yen, Tan, Glorijoy Shi En, Htun, Htet Lin, Phua, Hwee Pin, Kyaw, Win Mar, Guo, Huiling, Cui, Lin, Mak, Tze Minn, Poh, Bee Fong, Wong, Judith Chui Ching, Setoh, Yin Xiang, Ang, Brenda Sze Peng, Chow, Angela Li Ping

“…Ward air exhaust filters were tested for SARS-CoV-2. Results: In total, there were 47 cases, comprising 29 patients, nine staff, six visitors and three household contacts. …”
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CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment by Greensmith, Robert, Lape, Isadora T., Riella, Cristian V., Schubert, Alexander J., Metzger, Jakob J., Dighe, Anand S., Tan, Xiao, Hemmer, Bernhard, Rau, Josefine, Wendlinger, Sarah, Diederich, Nora, Schütz, Anja, Riella, Leonardo V.

“…However, current methods, relying on hybridization or sequencing, are unsuitable for point-of-care settings. In contrast, CRISPR-based-diagnostics offer high sensitivity and specificity for point-of-care applications. …”
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Pet loss in Singapore: understanding anticipatory grief and the role of advance care planning by Harindran, Ravin

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Person-centred care for dementia patients (back-end and front-end development) by Leow, Mandfred Hong Jie

“…This report documents the development and transition of the Person-Centred Care System (PEAR) from a monolithic .NET 5-based application to a microservices architecture with ReactJS for the front end. …”
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Creation of a world class manufacturing system in a health-care company by Tay, Albert Kim Chuan.

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Automated mean arterial pressure control for postoperative patients in intensive care conditions by Ma, Jie

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The fate and transformation of pharmaceutical and personal care products in wastewater treatment plants – (ii) by Ng, Thai Yeng

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Pear person-centred care for dementia patients (front end Android app) by Ng, Jian Xiong

“…With so much emphasis placed on the individualism of eachpatient, this could stress out the caregivers in a care centre. To reduce the workload on the caregiver, technology could play apart and give rise to more effective healthcare services.In this project, a Person-Centred Care system was created to assist the caregivers who were responsible for taking care of their patients and increasing the efficiency of dementia care in a care centre. …”
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Improving clinical care of patients in Nipah outbreaks: moving beyond 'compassionate use' by Hassan, MZ, Rojek, A, Olliaro, P, Horby, P

“…Current care relies on supportive measures and the ‘compassionate use’ of unapproved drugs like ribavirin and remdesivir. …”

Investigating the health and care needs of pregnant women with multiple long-term conditions by D'Arcy, R

Sharing is caring? International Society for Pharmacoepidemiology review and recommendations for sharing programming code by Tazare, J, Wang, SV, Gini, R, Prieto Alhambra, D, Arlett, P, Morales Leaver, DR, Morton, C, Logie, J, Popovic, J, Donegan, K, Schneeweiss, S, Douglas, I, Schultze, A

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…We address this gap by integrating large-scale primary-care and genetic data from multiple studies to interrogate multimorbidity patterns and producing digital resources to support future research.…”

Factors affecting duration of SARS-Cov-2 viral shedding in mildly symptomatic patients isolated in a community facility by Cheng, Hui Mei, Zhao, Xiahong, Lim, Wei Shyann, Tan, Beatrice Jia Min, Tey, Hong Liang

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